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| 1 | Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population:Findings from the China Cardiometabolic Disease and Cancer Cohort(4C)Study显示文摘Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains inconclusive.We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population.Methods The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study.A total of 105,922 community-dwelling adults aged≥40 years underwent the oral glucose tolerance test and uric acid assessment.The nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive models.Results A total of 30,941 men and 62,361 women were eligible for the current analysis.Generalized additive models verified the inverted U-shaped association between glycemic indices and SUA levels,but with different inflection points in men and women.The thresholds for FPG,2 h-PG,and HbA1 c for men and women were 6.5/8.0 mmol/L,11.0/14.0 mmol/L,and 6.1/6.5,respectively(SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices).Conclusion An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes,while the inflection points were reached earlier in men than in women. | ZHU Yuan Yue ZHENG Rui Zhi WANG Gui Xia CHEN Li SHI Li Xin SU Qing XU Min XU Yu CHEN Yu Hong YU Xue Feng YAN Li WANG Tian Ge ZHAO Zhi Yun QIN Gui Jun WAN Qin CHEN Gang GAO Zheng Nan SHEN Fei Xia LUO Zuo Jie QIN Ying Fen HUO Ya Nan LI Qiang YE Zhen ZHANG Yin Fei LIU Chao WANG You Min WU Sheng Li YANG Tao DENG Hua Cong ZHAO Jia Jun CHEN Lu Lu MU Yi Ming TANG Xu Lei HU Ru Ying WANG Wei Qing NING Guang LI Mian LU Jie Li BI Yu Fang | 2021 | Biomedical and Environmental Sciences2021，34，1： | 2 |
| 2 | Effect of sulfate solu- tion on the frost resistance of concrete with and without steel fiber reinforce - ment 显示文摘 | MIAO Chang - wen MU Ru TIAN Qian | 2002 | Cement and Concrete2002，32，1： | 1 |
| 3 | Effect of chloride salt, freeze-thaw cycling and externally applied load on the per- formance of the concrete显示文摘 | SUN Wei MU Ru LUO Xin | 2002 | Cement atld Concrete Research2002，32，12： | 1 |
| 4 | Association of depression and anxiety in patients with irritable bowel syndrome显示文摘 | Cruz Ruíz MA Ortíz Herrera RB Mu(n)iz Jurado D | 2007 | Rev Gastroenterol Mex2007，72，1： | 1 |
| 5 | Interaction between loading,freeze-thaw cycles,and chloride salt attack of concrete with and without steel fiber reinforcement显示文摘 | RU MU CHANGWEN MIAO XIN LUO WEI SUN | 2002 | Cement and Concrete Research2002，32，7： | 1 |
| 6 | Effect of chloride salt,freeze-thaw cycling and externally applied load on the performance of the concrete显示文摘 | SUN Wei MU Ru LUO Xin | 2002 | Cement and Concrete Research2002，，32： | 1 |
| 7 | A survey on image segmentation 显示文摘 | Ru S K Mu J K | 1981 | Pattern Recognition1981，139，1： | 1 |
| 8 | Trifloxystrobin,a New Active Ingredient for the Control of Black Sigatoka in Banana Cultivation in Colombia and Ecuador显示文摘 | PINZón RUíz C TORO R MU(n)OZ R | 2003 | Pflanzenschutz-nachrichten Bayer2003，56，2： | 1 |
| 9 | Effect of chloride salt, freeze–thaw cycling and externally applied load on the performance of the concrete显示文摘 | Wei Sun Ru Mu Xin Luo Changwen Miao | 2002 | Cement and Concrete Research2002，，12： | 1 |
| 10 | Properties of concrete subjected to freezing and thawing under sulphate attack显示文摘 | Mu Ru Miao Changwen Liu Jiaping | 2001 | Indian Concrete Journal2001，75，7： | 1 |
| 11 | Effect of sulfate solution on the frost resistance of concrete with and without steel fiber reinforcement显示文摘 | Changwen Miao Ru Mu | | 0，，32： | 1 |
| 12 | Effect of chloride salt,freeze-thaw cycling and externaLly applied load on the performance of the concrete显示文摘 | SUN Wei MU Ru LUO Xin | 2002 | Cem Concr Res2002，32，12： | 1 |
| 13 | Properties of Concrete Subjected to Freezing and Thawing under Sulphate Attack显示文摘 | Mu Ru Miao Changwen Liu Jiaping | 2001 | Indian Concrete Journal2001，75，7： | 1 |
| 14 | Effect of chloride salt, freeze- thaw cycling and externally applied load on the performance of the concrete显示文摘 | SUN Wei MU Ru | 2002 | Cement and Concrete Researech2002，32，12： | 1 |
| 15 | Effect of chloride salt, freeze-thaw cycling and externally applied load on the performance of the concrete显示文摘 | SUN Wei MU Ru LUO Xin | 2002 | Cement and Concrete Research2002，32，12： | 1 |
| 16 | Effect of chloride salt,freeze-thaw cycling and externally applied load on the performance of the concrete显示文摘 | Sun Wei Mu Ru Luo Xin | 2002 | Cement and Concrete Research2002，32，12： | 1 |
| 17 | Effect of sulfate solution on the frost resistance of concrete with and without steel fiber rein- forcement显示文摘 | MIAO Changwen MU Ru TIAN Qian | 2002 | Cement and Concrete Research2002，32，1： | 1 |
| 18 | Effect of chloride salt,freeze-thaw cycling and externally applied load on the performance of the concrete 显示文摘 | SUN Wei MU Ru LUO Xin | 2002 | Cem Conc Res2002，32，12： | 1 |
| 19 | The telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas显示文摘 | Dong Qian Bin Zhang Li‐Ru He Mu‐Yan Cai Shi‐Juan Mai Yi‐Ji Liao Yan‐Hui Liu Marie C Lin Xiu‐Wu Bian Yi‐Xin Zeng Jun‐Jian Huang Hsiang‐Fu Kung Dan Xie | 2013 | J Pathol2013，，5： | 1 |
| 20 | Interaction between loading,freeze-thaw cycles,and chloride salt attack of concrete with and without steel fiber reinforcement显示文摘 | Mu Ru Miao Changwen Luo Xin Sun Wei | 2002 | Cement and Concrete Research2002，32，7： | 1 |
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