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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 2 | Interferon-γ: Promising therapeutic target in atherosclerosis显示文摘Atherosclerosis is a chronic inflammatory disorder of the vasculature and is the primary cause of cardiovascular disease(CVD). CVD is currently the world's leading cause of death and the numbers are predicted to rise further because of a global increase in risk factors such as diabetes and obesity. Current therapies such as statins have had a major impact in reducing mortality from CVD. However, there is a marked residual CVD risk in patients on statin therapy. It is therefore important to understand the molecular basis of this disease in detail and to develop alternative novel therapeutics. Interferon-γ(IFN-γ) is a pro-inflammatory cytokine that is often regarded as a master regulator of atherosclerosis development. IFN-γ is able to influence several key steps during atherosclerosis development, including pro-inflammatory gene expression, the recruitment of monocytes from the blood to the activated arterial endothelium and plaque stability. This central role of IFN-γ makes it a promising therapeutic target. The purpose of this editorial is to describe the key role IFN-γ plays during atherosclerosis development, as well as discuss potential strategies to target it therapeutically. | Joe WE Moss Dipak P Ramji | 2015 | World Journal of Experimental Medicine2015,5,3: | 7 |
| 3 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017,6,1: | 6 |
| 4 | Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography显示文摘AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures. | Michael P Swan Michael J Bourke Stephen J Williams Sina Alexander Alan Moss Rick Hope David Ruppin | 2011 | World Journal of Gastroenterology2011,17,45: | 6 |
| 5 | Phenotypic analysis of antigen-specific T lymphocytes显示文摘 | Moss P A H Goulter P J R | 1996 | Science1996,274,: | 1 |
| 6 | Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome:A worldwide report显示文摘 | SCHWARTZ P J LOCATI E H MOSS A J | 1991 | Circulation1991,84,2: | 1 |
| 7 | Esophageal carcinoma: pretherapy staging by computed tomography 显示文摘 | Moss AA Schnyder P Thoeni RF | 1981 | A JR Am J Roent- genol1981,136,6: | 1 |
| 8 | The membrane fusion step of vaccinia virus entry is cooperatively mediated by multiple viral proteins and host cell components 显示文摘 | LALIBERTE J P WEISBERG A S MOSS B | 2011 | Plns Pathog2011,7,12: | 1 |
| 9 | An incremental server for scheduling overloaded real-time systems显示文摘 | MEJIA-ALVAREZ P MELHEM R MOSSE D AYDIN H | 2003 | IEEE Transactions on Computers2003,52,10: | 1 |
| 10 | The behavior of bearings used for seismic isolation under shear and axial load 显示文摘 | P J Moss N Cook A J Carr | 1999 | Earthquake Spectra1999,15,2: | 1 |
| 11 | Helicobacter and gastric malignancies显示文摘 | Moss SF Malfertheiner P | 2007 | Hell Cobacter2007,12,1: | 1 |
| 12 | 'soft' skills and race:an investigation of Black men's employment problems显示文摘 | Moss P Tilly C | | 0,,03: | 1 |
| 13 | Esophageal carcinoma: pretherapy staging by comuted tomography 显示文摘 | Moss AA Schnyder P Thoeni RF | 1981 | AIR1981,136,6: | 1 |
| 14 | Long term observation of RC-bridge using changes in natural frequency显示文摘 | ASKEGAARD V MOSSING P | | 0,,1: | 1 |
| 15 | Can there be validity without 'reliability'? 显示文摘 | Moss P A | 1994 | Educational Researcher1994,23,2: | 1 |
| 16 | Design Method for Bridges on Lead-rubber Bearings显示文摘 | Turkington D H Carr A J Cooke N Moss P J | 1989 | Journal of Structural Engineering1989,115,12: | 1 |
| 17 | Assessment of poste- rior spinal cord function with electrical perception thresh-old in spinal cord injury显示文摘 | Kramer JL Moss A J Taylor P | 2008 | J Neurotrauma2008,25,8: | 1 |
| 18 | Vaccinia vi- rus H7 protein contributes to the formation of cres- cent membrane precursors of immature virions显示文摘 | Satheshkumar P S Weisberg A Moss B | 2009 | Journal of Virology2009,83,17: | 1 |
| 19 | Some effect of temperature regime duringgrainfilling on wheat quality 显示文摘 | Randail P J Moss H J | 1990 | Australian Journal of AgricultureResearch1990,41,4: | 1 |
| 20 | The meaning and consequences of 'reliability' 显示文摘 | Moss P A | 2004 | Journal of Educational and Behavioral Statis- tics2004,29,2: | 1 |