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| 1 | Scaffolds based therapy for osteochondral lesions of the talus:A systematic review显示文摘AIM To clarify the effectiveness of scaffold-based therapy for osteochondral lesions of the talus(OLT). METHODS A systematic search of MEDLINE and EMBASE databases was performed during August 2016 and updated in January 2017. Included studies were evaluated with regard to the level of evidence(LOE) and quality of evidence(QOE) using the Modified Coleman Methodology Score. Variable reporting outcome data, clinical outcomes, and the percentage of patients who returned to sport at previous level were also evaluated. RESULTS Twenty-eight studies for a total of 897 ankles were included; 96% were either LOE Ⅲ or Ⅳ. Studies were designated as either of poor or fair quality. There were 30 treatment groups reporting six different scaffold repair techniques: 13 matrix-induced autologous chondrocyte transplantation(MACT), nine bone marrow derived cell transplantation(BMDCT), four autologous matrixinduced chondrogeneis(AMIC), and four studies of other techniques. The categories of general demographics(93%) and patient-reported outcome data(85%) were well reported. Study design(73%), imaging data(73%), clinical variables(49%), and patient history(30%) were also included. The weighted mean American Orthopaedic Foot and Ankle Society(AOFAS) score at final follow-up was: 86.7 in MACT, 88.2 in BMDCT, and 82.3 in AMIC. Eight studies reported that a weighted mean of 68.3% ofpatients returned to a previous level of sport activity. CONCLUSION Scaffold-based therapy for OLT may produce favorable clinical outcomes, but low LOE, poor QOE, and variability of the data have confounded the effectiveness of this treatment. | Yoshiharu Shimozono Youichi Yasui Andrew W Ross Wataru Miyamoto John G Kennedy | 2017 | World Journal of Orthopedics2017，8，10： | 4 |
| 2 | Chirality in synthetic agrochemicals: bioactivity and safety considera- tion显示文摘 | Kurihara N Miyamoto J Paulson G D | 1997 | Pure Appl Chem1997，69，9： | 1 |
| 3 | Development of a digital imaging system for objective measurement of hyper pigmented spots on the face显示文摘 | Miyamoto K Takiwaki H Hillebrand G | 2002 | Skin Res Technol2002，8，4： | 1 |
| 4 | Notch signaling-constantly on the move 显示文摘 | Nichols JT Miyamoto A Weinmaster G | 2007 | Traffics2007，8，8： | 1 |
| 5 | 查看详情显示文摘 | Kudo S Okumura H Miyamoto G Ishizaki T | | 0，，： | 1 |
| 6 | Notch signaling constantly on the move显示文摘 | Nichols JT Miyamoto A Weinmaster G | 2007 | Traffic2007，8，8： | 1 |
| 7 | Fluid analysis code 'FLOW-3D' application in coating显示文摘 | Miyamoto Y Kami S Taimusu P G | 2002 | Japanese Journal of Paper Technology2002，43，8： | 1 |
| 8 | Three new acylated triterpene saponins from Acathophyllum squarrosum显示文摘 | Gaidi G Miyamoto T Rustaiyan A | 2001 | J Nat Prod2001，64，7： | 1 |
| 9 | Effects of saline water irrigation on soil salinity, pecan tree growth and nut production 显示文摘 | Miyamoto S Riley T Gobran G | 1986 | Irrigation Science1986，7，2： | 1 |
| 10 | Laminin 5 expression protects against anoikis at aerogenous spread and lepidic growth of human lung adenocarcinoma显示文摘 | Kodama K Ishii G Miyamoto S | 2005 | Int J Cancer2005，116，6： | 1 |
| 11 | Formation of uhrafine grained ferrite by warm deformation of lath martensite in low-alloy steels with different carbon content显示文摘 | Poorganji B Miyamoto G Maki T | 2008 | Scripta Materialia2008，59，3： | 1 |
| 12 | Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function显示文摘 | Duncan G Miyamoto S Gu H | 2002 | Brain Res2002，951，2： | 1 |
| 13 | Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function显示文摘 | Duncan G Miyamoto S Gu H | 2002 | Brain Res2002，951，1： | 1 |
| 14 | Effect of carbon content on variant pairing of martensite in Fe- C alloys 显示文摘 | Stormvinter A Miyamoto G Furuhara T | 2012 | Acta Materialia2012，60，： | 1 |
| 15 | Multiphase crystallography in the nucleation of intragranular ferrite on MnS+V(C, N) complex precipitate in austenite显示文摘 | FURUHARA T SHINYOSHI T MIYAMOTO G YAMAGUCHI J SUGITA N KIMURA N TAKEMURA N MAKI T | 2003 | ISIJ International2003，43，12： | 1 |
| 16 | The many facets of Notch ligands显示文摘 | Souza BD Miyamoto A Weinmaster G | 2008 | Oncogene2008，27，228： | 1 |
| 17 | Chirality in Synthetic Agrochemicals: Bioactivity and Safety Consideration显示文摘 | KURIHARA N MIYAMOTO J PAULSON G D | 1997 | Pure Appl Chem1997，69，： | 1 |
| 18 | Ligand-induced signaling in the absence of furin processing of Notchl 显示文摘 | Bush G diSibio G Miyamoto A | 2001 | Dev Biol2001，229，2： | 1 |
| 19 | Comprehensive gene expression analysis by transcript profiling显示文摘 | Donson J Fang Y Espiritu-Santo G Xing W Salazar A Miyamoto S Armendarez V Volkmuth W | 2002 | Plant Mol Biol2002，48，： | 1 |
| 20 | Distribution and molecular characterization of Corynespora cassiicola isolates resistant to boscalid显示文摘 | T Miyamoto H Ishii G Stammler | 2010 | Plant Pathology2010，59，： | 1 |
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