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| 1 | Plasma and platelet serotonin levels in patients with liver cirrhosis显示文摘AIM: To analyze the relationship between plasma and platelet serotonin levels and the degree of liver insufficiency. METHODS: The prospective study included 30 patients with liver cirrhosis and 30 healthy controls. The degree of liver failure was assessed according to the Child-Pugh classification. Platelet and platelet poor plasma serotonin levels were determined. RESULTS: The mean plasma serotonin level was higher in liver cirrhosis patients than in healthy subjects (215.0 ± 26.1 vs 63.1 ± 18.1 nmol/L; P < 0.0001). The mean platelet serotonin content was not significantly different in patients with liver cirrhosis compared with healthy individuals (4.8 ± 0.6; 4.2 ± 0.3 nmol/platelet; P > 0.05). Plasma serotonin levels were significantly higher in Child- Pugh grade A/B than in grade C patients (246.8 ± 35.0 vs 132.3 ± 30.7 nmol/L; P < 0.05). However, platelet serotonin content was not significantly different between Child-Pugh grade C and grade A/B (4.6 ± 0.7 vs 5.2 ± 0.8 nmol/platelet; P > 0.05). CONCLUSION: Plasma serotonin levels are significantly higher in patients with cirrhosis than in the controls and represent the degree of liver insufficiency. In addition, platelet poor plasma serotonin estimation is a better marker for liver insufficiency than platelet serotonin content. | ■or■e M ulafi Duko S Mirkovi Miodrag D Vukevi Jelena S Rudi | 2007 | World Journal of Gastroenterology2007，13，43： | 5 |
| 2 | Meta-analysis of stent thrombosis after drug-eluting stent implantation: 4-year follow-up显示文摘背景 Drug-eluting stents (DES ) 是在冠的动脉疾病的经皮的治疗使用的最普通的设备。最近,关于他们的安全侧面有一颗增加的担心,与赤裸的金属 stents (BMS ) 相比的特别地晚并且很迟了的 stent 血栓率。学习的目的是近来并且很晚比较报导发生在从有到四 years.Methods 的一个扩大后续时期的出版临床的研究的病人的 DES 和 BMS 的 stent 血栓搜索策略被开发识别在 BMS 和可得到的 DES 的晚或很迟了的血栓上报导的出版物通过 MEDLINE 和 Cochrane 图书馆数据库。二个独立评论家估价了合格研究并且提取了数据。机会比率(或) 为每结果被计算并且与 95% 信心间隔(CI ) 介绍了 .Results 十四使随机化控制试用,是使失明的至少单身者,被识别。近来在发生没有差别,在病人的很迟了的 stent 血栓与与 BMS 对待的病人相比与 DES 对待(迟了或 0.55, 95%Cl 0.23-1.31 和晚 / 很迟了的 OR=1.08, 95%CI 0.61-1.91 ).Conclusions 安全侧面 DES 以 stent 血栓类似于 BMS。我们没近来并且很晚发现增加的风险的证据为 DES 的血栓。 | Natasa M Milic Biljana J Parapid Miodrag C Ostojic Milan A Nedeljkovic Jelena M Marinkovic | 2010 | Chinese Medical Journal2010，，24： | 2 |
| 3 | Non-linear analysis of plate and folded plate structures by the finite strips method 显示文摘 | Miodrag S Dragan M | 1987 | Engineering Computations1987，4，1： | 1 |
| 4 | Reduced Complexity Iterative Decoding of Low-density Parity Check Codes based on Belief Propagation显示文摘 | Fossorier M P C Miodrag M Hideki I | 1999 | IEEE Transactions on Communications1999，47，5： | 1 |
| 5 | Worst and best-case coverage in sensor networks显示文摘 | Farinaz K and Miodrag P | 2005 | IEEE Transactions on Mobile Computing2005，4，1： | 1 |
| 6 | Membrane fouling daring cross-flow microfiltration of polyporus squamosus fermentation broth显示文摘 | Darko M Krstic Sinisa L Markov Miodrag N Teki | 2001 | Biochemical Engineering Journal2001，19，： | 1 |
| 7 | Probing the lignin nanomechanical properties and lignin-lignin interactions using the atomic force microscopy显示文摘 | Miodrag M Ivan B Melanie R | 2001 | Chemical Physics Letters2001，347，： | 1 |
| 8 | Study of the lignin compound supramolecular structure by combination of near-field scanning optical microscopy and atomic force microscopy显示文摘 | MIODRAG M KSENIJA R MILORAD J | 2004 | Colloids and Surfaces B:Biointerface2004，34，： | 1 |
| 9 | Generic Cryptographic Weakness of K-normal Boolean Founctions in Certain Stream Ciphers and Cryptanalysis of Grain-128显示文摘 | Miodrag J M Sugata G Goutam P | 2012 | Periodica Mathematica Hungarica2012，65，2： | 1 |
| 10 | New Resampling Algorithms for Particle Filters显示文摘 | Miodrag Bolic' Peter M Djuric' Sangjin Hong | 2003 | ICASSP2003 (S1845-5921)2003，2，： | 1 |
| 11 | Hydrothermal syn-thesis of Li4 Ti5 O12-C nanostructured composites:mor-phology and electrochemical performance显示文摘 | Milica V Vana S Miodrag M | | 0，，： | 1 |
| 12 | Analysis of the spreader track wheels premature damages显示文摘 | Miodrag A Arsi6 Srd-an M Bonjak Zoran D Odanovi6 | 2012 | Engineering Failure Analysis2012，20，： | 1 |
| 13 | Visualization of artificial lignin supramolecular structures 显示文摘 | Miodrag M Milorad J Ksenija R | 2000 | Scanning:J Scanning Microscopies2000，22，5： | 1 |
| 14 | A membrane fouling daring cross-flow micro filtration of polypore squamosus fermentation broth显示文摘 | Darko M Krstic Sinisa L Nlarkov Miodrag N Teki | 2001 | Biochemical Engineering Journal2001，19，： | 1 |
| 15 | Study of the lignin model compound supramolecular structure by combination of near-field scanning optical microscopy and atomic force microscopy显示文摘 | Miodrag M Ksenija R Milorad J | 2004 | Colloids and Surfaces B:Biointerfaces2004，34，： | 1 |
| 16 | Synthesis and characterization of LiFePO4/C composite obtained by sonochemical method显示文摘 | DRAGANA J MIODRAG M NIKOLA C BOSTJAN J SLAVKO M DRAGAN U | 2008 | Solid State Ionics2008，179，： | 1 |
| 17 | Validation of the chronic liver disease questionnaire in Serbian patients显示文摘AIM:To translate into Serbian and to investigate the validity of the cross-culturally adapted the chronic liver disease questionnaire(CLDQ).METHODS:The questionnaire was validated in 103 consecutive CLD patients treated between October 2009 and October 2010 at the Clinic for Gastroenterology,Clinical Centre of Serbia,Belgrade(Serbia).Exclusion criteria were:age < 18 years,psychiatric disorders,acute complications of CLD(acute liver failure,variceal bleeding,and spontaneous bacterial peritonitis),hepatic encephalopathy(grade > 2)and liver transplantation.Evaluation of the CLDQ was done based on the following parameters:(1)acceptance is shown by the proportion of missing items;(2)internal reliabilities were assessed for multiple item scales by using Cronbach alpha coefficient;and(3)in order to assess whether the allocation of items in the domain corresponds to their distribution in the original questionnaire(construction validity),an exploratory factor analysis was conducted.Discriminatory validity was determined by comparing the corresponding CLDQ score/sub-score in patients with different severity of the diseases.RESULTS:The Serbian version of CLDQ questionnaire completed 98% patients.Proportion of missing items was 0.06%.The total time needed to fill the questionnaire was ranged from 8 to 15 min.Assistance in completing the questionnaire required 4.8% patients,while 2.9% needed help in reading,and 1.9% involved writing assistance.The mean age of the selected patients was 53.8 ± 12.9 years and 54.4% were men.Average CLDQ score was 4.62 ± 1.11.Cronbach's alpha for the whole scale was 0.93.Reliability for all domains was above 0.70,except for the domain 'Activity'(0.49).The exploratory factor analysis model revealed 6 factors with eigenvalue of greater than 1,explaining 69.7% of cumulative variance.The majority of the items(66%)in the Serbian version of the CLDQ presented the highest loading weight in the domain assigned by the CLDQ developers:'Fatigue'(5/5),'Emotional function'(6/8),'Worry'(5/5),'Abdominal symptoms'(0/3),'Activity'(0/3),'Systemic symptoms'(3/5).The scales 'Fatigue' and 'Worry' fully corresponded to the original.The factor analysis also revealed that the factors 'Activity' and 'Abdominal symptoms' could not be replicated,and two new domains 'Sleep' and 'Nutrition' were established.Analysis of the CLDQ score/sub-score distribution according to disease severity demonstrated that patients without cirrhosis had lower total CLDQ score(4.86 ± 1.05)than those with cirrhosis Child's C(4.31 ± 0.97).Statistically significant difference was detected for the domains 'Abdominal symptoms' [F(3)= 5.818,P = 0.001] and 'Fatigue' [F(3)= 3.39,P = 0.021].Post hoc analysis revealed that patients with liver cirrhosis Child's C had significantly lower sub-score 'Abdominal symptoms' than patients without cirrhosis or liver cirrhosis Child's A or B.For domain 'Fatigue',patients with cirrhosis Child's C had significantly lower score,than non-cirrhotic patients.CONCLUSION:The Serbian version of CLDQ is well accepted and represents a valid and reliable instrument in Serbian sample of CLD patients. | Dusan Dj Popovic Nada V Kovacevic Darija B Kisic Tepavcevic Goran Z Trajkovic Tamara M Alempijevic Milan M Spuran Miodrag N Krstic Rada S Jesic Zobair M Younossi Tatjana D Pekmezovic | 2013 | World Journal of Gastroenterology2013，19，30： | 1 |
| 18 | Synthesis of characterization of LiFePO4/C composite obtained by sonochemical method显示文摘 | DRAGANA J MIODRAG M NIKOLA C | 2008 | Solid State Ionics2008，179，1112： | 1 |
| 19 | Resampling Algorithms and Architectures for Distributed Particle Filters 显示文摘 | Miodrag B Djuric P M Sangjin H | 2005 | IEEE Transactions on Signal Processing2005，53，7： | 1 |
| 20 | Finite precision effect on performance and complexity of particle filters for bearing - only tracking 显示文摘 | Miodrag B Hong S J Petar M D | 2002 | Department of Electrical and Computer Engineering Stony Brook2002，1，10： | 1 |
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