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| 1 | β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas:role in the regulation of response to somatostatin analogue treatment in patients with acromegaly显示文摘Recent in vitro studies highlighted G protein-coupled receptor kinase(GRK)2 andβ-arrestins as important players in driving somatostatin receptor(SSTR)desensitization and trafficking.Our aim was to characterize GRK2 andβ-arrestins expression in different pituitary adenomas and to investigate their potential role in the response to somatostatin analog(SSA)treatment in GHsecreting adenomas(GHomas).We evaluated mRNA expression of multiple SSTRs,GRK2,β-arrestin 1,andβ-arrestin 2 in 41pituitary adenomas(31 GHomas,6 nonfunctioning[NFPAs],and 4 prolactinomas[PRLomas]).Within the GHomas group,mRNA data were correlated with the in vivo response to an acute octreotide test and with the GH-lowering effect of SSA in cultured primary cells.β-Arrestin 1 expression was low in all 3 adenoma histotypes.However,its expression was significantly lower in GHomas | Gatto F Feelders R van der Pas R Kros JM Dogan F van Koetsveld PM van der Lelij AJ Neggers SJ Minuto F de Herder W Lamberts SW Ferone D Hofland LJ | 2013 | 中国神经肿瘤杂志2013，11，4： | 2 |
| 2 | Hypothalamic-pituitary-adrenal axis impairment in the pathogenesis of rheumatoid arthritis and polymyalgia rheumatica显示文摘 | Cutolo M Foppiani L Minuto F | 2002 | J Endocrinol Invest2002，25，10： | 1 |
| 3 | Insulin-like growth factor-Ⅰ in human malnutrition:relationship with some body composition and nutritional parameters 显示文摘 | Minuto F Barreca A Adami GF | 1989 | JPEN J Parenter Enteral Nutr1989，13，4： | 1 |
| 4 | Application of an emulsifiable mixture of 1,3-dichloropropene and chloropicrin against root knot nematodes and soilborne fungi for greenhouse tomatoes in Italy显示文摘 | Minuto A Gullino M L Lamberti F | | 0，，25： | 1 |
| 5 | Insulin -like factor (IGF-Ⅰ)and angiographically documented coronary attery disease显示文摘 | Spallarossa P Bumelli C Minuto F | 1996 | Am J Cardiol1996，77，2： | 1 |
| 6 | Secondary diabetes associated with principal endocrinopathies:the impact of new treatment modalities显示文摘 | Resmini E Minuto F Colao A | 2009 | Acta Diabetol2009，46，2： | 1 |
| 7 | 显示文摘 | Spallarossa P Brunelli C Minuto F | 1996 | Am J Cardiol1996，77，2： | 1 |
| 8 | Secondary diabetes associ- ated with principal endocrinopathies: the impact of new treatment modalities 显示文摘 | Resmini E Minuto F Colao A | 2009 | Acta diabetohigica2009，46，2： | 1 |
| 9 | Insulin- like growth factor - 1 and angiographically documented coronary artery disease 显示文摘 | SPALLAROSSA P BRUNELLI C MINUTO F | 1996 | Am J Cardiol1996，77，2： | 1 |
| 10 | Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities显示文摘 | RESMINI E MINUTO F COLAO A | 2009 | Acta Diabetol2009，46，2： | 1 |
| 11 | The IGF system and bone显示文摘 | Minuto F Palermo C Arvigo M | 2005 | J Endocrinol Invest2005，28，8： | 1 |
| 12 | Application of an emulsifiable mixture of 1,3-dichloropropene and chloropicrin against root knot nematodes and soilborne fungi for greenhouse tomatoes in Italy显示文摘 | Minuto A Gullino M L Lamberti F | 2006 | Crop Protection2006，25，： | 1 |
| 13 | Wolfram syndrome (diabetes insipidus,diabetes,optic atrophy,and deafness):clinical and genetic study显示文摘 | d'Annunzio G Minuto N D'Amato E de Toni T Lombardo F Pasquali L Lorini R | | 0，，： | 1 |
| 14 | Insulin - like growth factor - 1 in human,malnutritior : relationship with some body corn-position and nutritional parameters 显示文摘 | MINUTO F BARRECA A ADAMI GF | 1989 | JPEN J Parenter Enteral Nutr1989，13，： | 1 |
| 15 | Evaluation of growth hormone administration in patients with chronic heart failure secondary to coronary artery disease显示文摘 | Spallarossa P Rossettin P Minuto F | 1999 | Am J Cardiol1999，84，： | 1 |
| 16 | Application of an emulsifiable mixture of 1,3-dichloropropene and chloropicrin against root knot nematodes and soilborne fungi for greenhouse tomatoes in Italy 显示文摘 | Minuto A Gullino ML Lamberti F D’Addabbo T Tescari E Ajwa H Garibaldi A | 2006 | Crop Protect2006，25，12： | 1 |
| 17 | Growth factors in the ovary显示文摘 | Giordano g Barreca A Minuto F | 2002 | J Endo- crinol Invest2002，15，： | 1 |
| 18 | Insulin-like growth factor-I and angiographically documented coronary artery disease显示文摘 | Spallarossa P Brunelli C Minuto F | 1996 | Am J Cardiol1996，77，2： | 1 |
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