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| 1 | Climate Change and Its Effects on Runoff of Kaidu River, Xinjiang, China:A Multiple Time-scale Analysis显示文摘This paper applied an integrated method combining grey relation analysis, wavelet analysis and statistical analysis to study climate change and its effects on runoff of the Kaidu River at multi-time scales. Major findings are as follows: 1) Climatic factors were ranked in the order of importance to annual runoff as average annual temperature, average temperature in autumn, average temperature in winter, annual precipitation, precipitation in flood season, average temperature in summer, and average temperature in spring. The average annual temperature and annual precipi- tation were selected as the two representative factors that impact the annual runoff. 2) From the 32-year time scale, the annual runoff and the average annual temperature presented a significantly rising trend, whereas the annual precipita- tion showed little increase over the period of 1957-2002. By changing the time scale from 32-year to 4-year, we ob- served nonlinear trends with increasingly obvious oscillations for annual runoff, average annual temperature, and annual precipitation. 3) The changes of the runoff and the regional climate are closely related, indicating that the runoff change is the result of the regional climate changes. With time scales ranging from 32-year, 16-year, 8-year and to 4-year, there are highly significant linear correlations between the annual runoff and the average annual temperature and the annual precipitation. | XU Jianhua CHEN Yaning JI Minhe LU Feng | 2008 | Chinese Geographical Science2008，18，4： | 33 |
| 2 | Wavelet Analysis and Nonparametric Test for Climate Change in Tarim River Basin of Xinjiang During 1959-2006显示文摘Using wavelet analysis,regression analysis and the Mann-Kendall test,this paper analyzed time-series(1959-2006) weather data from 23 meteorological stations in an attempt to characterize the climate change in the Tarim River Basin of Xinjiang Uygur Autonomous Region,China.Major findings are as follows:1) In the 48-year study period,average annual temperature,annual precipitation and average annual relative humidity all presented nonlinear trends.2) At the 16-year time scale,all three climate indices unanimously showed a rather flat before 1964 and a detectable pickup thereafter.At the 8-year time scale,an S-shaped nonlinear and uprising trend was revealed with slight fluctuations in the entire process for all three indices.Incidentally,they all showed similar pattern of a slight increase before 1980 and a noticeable up-swing afterwards.The 4-year time scale provided a highly fluctuating pattern of periodical oscillations and spiral increases.3) Average annual relative humidity presented a negative correlation with average annual temperature and a positive correlation with annual precipitation at each time scale,which revealed a close dynamic relationship among them at the confidence level of 0.001.4) The Mann-Kendall test at the 0.05 confidence level demonstrated that the climate warming trend,as represented by the rising average annual temperature,was remarkable,but the climate wetting trend,as indicated by the rising annual precipitation and average annual relative humidity,was not obvious. | XU Jianhua CHEN Yaning LI Weihong JI Minhe DONG Shan HONG Yulian | 2009 | Chinese Geographical Science2009，19，4： | 14 |
| 3 | 高温胁迫对杧果幼苗生理生化指标的影响显示文摘通过测定高温胁迫下四季杧与台农一号杧一年生嫁接苗叶片生理生化指标的变化,探讨其耐热的生理生化机制。结果表明:随着高温胁迫时间的延长,四季杧和台农一号杧的丙二醛(MDA)含量和相对电导率均明显上升,但四季杧的上升幅度和含量均明显高于台农一号杧。保护酶活性方面,高温胁迫处理后四季杧的SOD酶先下降后上升,而台农一号杧则是先上升后下降,且其含量明显高于四季杧;CAT酶的含量在高温胁迫后2个品种均减少,但四季杧CAT酶的含量明显高于台农一号杧。渗透调节物质游离脯氨酸在高温胁迫处理后含量明显高于处理前,但台农一号杧的上升程度明显高于四季杧。可溶性糖的含量在处理后12 h时,四季杧的含量明显高于台农一号杧,但在处理后72 h时,结果却相反。可溶性蛋白含量先下降后上升,并且四季杧的上升程度明显高于台农一号杧。胁迫处理后2个杧果品种的叶绿素含量和叶片相对含水量均下降,但四季杧的含量均明显低于台农一号杧。综合各项指标,初步推测台农一号杧比四季杧更耐热。 | CAN VAN TOAN 罗聪 何新华 董龙 DO MINH PHU | 2016 | 热带作物学报2016，37，1： | 12 |
| 4 | Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies显示文摘Cancer cells are well documented to rewire their metabolism and energy production networks to support and enable rapid proliferation, continuous growth, survival in harsh conditions, invasion, metastasis, and resistance to cancer treatments. Since Dr. Otto Warburg's discovery about altered cancer cell metabolism in 1930, thousands of studies have shed light on various aspects of cancer metabolism with a common goal to find new ways for effectively eliminating tumor cells by targeting their energy metabolism. This review highlights the importance of the main features of cancer metabolism, summarizes recent remarkable advances in this field, and points out the potentials to translate these scientific findings into life-saving diagnosis and therapies to help cancer patients. | Liem Minh Phan Sai-Ching Jim Yeung Mong-Hong Lee | 2014 | Cancer Biology & Medicine2014，11，1： | 11 |
| 5 | Aqueous extract of Taxus Chinensis (Pilger) Rehd inhibits lung carcinoma A549 cells through the epidermal growth factor receptor/mitogen-activated protein kinase pathway in vitro and in vivo显示文摘OBJECTIVE:To explore the anticancer mechanismof aqueous extract of Taxus Chinensis (Pilger) Rehd (AETC).METHODS: The serum pharmacological method was used to avoid interference from administration of the crude medicinal herbs. Eight purebred New Zealand rabbits were used for preparation of serum containing various concentrations of AETC. Forty-eightBalb/c-nu mice were used for in vivo experiments. The effects of serum containing AETC on the proliferation of A549 cells and expression levels of the epidermal growth factor receptor/mitogen-activated protein kinase(EGFR/MAPK) pathway-related proteins in vitro were investigated. Additionally, the effects on the growth of A549 xenografts in nudemice,and expression levels of the EGFR/MAPK pathway-related proteins in the xenografts,were investigated.RESULTS: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay revealed that the serum containing AETC significantly decreased the viability of A549 cells in a dose-dependent manner.Western blot showed that the serum containing various concentrations of AETC strongly reduced the levels of phospho-Jun N-terminal kinase(p-JNK) and phospho-extracellular signal-regulated kinase1/2(ERK1/2) while it increased the level of p-p38. However, no significant effects on the expression levels of JNK, ERK1/2, and p38 MAPK were found. In addition, an anticancer effect from AETC was observed invivo in the Balb/c-nu mice bearing A549xenografts.CONCLUSION: AETC has significant effects on the growth of A549 xenografts and on the activity of the EGFR/MAPK pathway. Therefore, AETC may be beneficial in lung carcinoma treatment. | Qijin Shu Minhe Shen Binbin Wang Qingli Cui Xiaoying Zhou Luming Zhu | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 10 |
| 6 | 拖拉机前桥半主动悬架特性参数匹配与控制显示文摘针对拖拉机减振性能差的问题,以定位阀输入电压与磁流变减振器励磁电流作为半主动悬架特性参数,进行了参数匹配台架试验。基于匹配试验结果,提出频域快速控制策略,采用LabView作为软件开发平台,以PCI6024E型数据采集卡为核心设计了半主动悬架控制系统,进行了试验验证。结果表明,定位阀输入电压与磁流变减振器励磁电流的合理匹配,可明显衰减悬架动态特性响应;所设计的半主动悬架控制系统能有效抑制簧载质量的垂向振动,改善拖拉机减振性能。 | 马然 朱思洪 Do Minh Cuong | 2013 | 农业机械学报2013，44，12： | 9 |
| 7 | Microstructure and anisotropic swelling behaviour of compacted bentonite/sand mixture显示文摘Pre-compacted elements(disks,torus) of bentonite/sand mixture are candidate materials for sealing plugs of radioactive waste disposal.Choice of this material is mainly based on its swelling capacity allowing all gaps in the system to be sealed,and on its low permeability.When emplaced in the gallery,these elements will start to absorb water from the host rock and swell.Thereby,a swelling pressure will develop in the radial direction against the host rock and in the axial direction against the support structure.In this work,the swelling pressure of a small scale compacted disk of bentonite and sand was experimentally studied in both radial and axial directions.Different swelling kinetics were identified for different dry densities and along different directions.As a rule,the swelling pressure starts increasing quickly,reaches a peak value,decreases a little and finally stabilises.FOr some dry densities,higher peaks were observed in the radial direction than in the axial direction.The presence of peaks is related to the microstructure change and to the collapse of macropores.In parallel to the mechanical tests,microstructure investigation at the sample scale was conducted using microfocus X-ray computed tomography(μCT).Image observation showed a denser structure in the centre and a looser one in the border,which was also confirmed by image analysis.This structure heterogeneity in the radial direction and the occurrence of macro-pores close to the radial boundary of the sample can explain the large peaks observed in the radial swelling pressure evolution.Another interesting result is the higher anisotropy found at lower bentonite dry densities,which was also analysed by means of μCT observation of a sample at low bentonite dry density after the end of test It was found that the macro-pores,especially those between sand grains,were not filled by swelled bentonite,which preserved the anisotropic microstructure caused by uniaxial compression due to the absence of microstructure collapse. | Simona Saba Jean-Dominique Barnichon Yu-Jun Cui Anh Minh Tang Pierre Delage | 2014 | Journal of Rock Mechanics and Geotechnical Engineering2014，6，2： | 8 |
| 8 | The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation显示文摘Among various immunoregulatory molecules,the B7 family of immune-checkpoint receptors consists of highly valuable targets for cancer immunotherapy.Antibodies targeting two B7 family co-inhibitory receptors,CTLA-4 and PD-1,have elicited long-term clinical outcomes in previously refractory cancer types and are considered a breakthrough in cancer therapy.Despite the success,the relatively low response rate(20–30%)warrants efforts to identify and overcome additional immune-suppressive pathways.Among the expanding list of T cell inhibitory regulators,V domain immunoglobulin suppressor of T cell activation(VISTA)is a unique B7 family checkpoint that regulates a broad spectrum of immune responses.Here,we summarize recent advances that highlight the structure,expression,and multi-faceted immunomodulatory mechanisms of VISTA in the context of autoimmunity,inflammation,and anti-tumor immunity. | Wenwen Xu TạMinh Hiếu Subramaniam Malarkannan Li Wang | 2018 | Cellular & Molecular Immunology2018，15，5： | 8 |
| 9 | 离子固化剂改性蒙脱土吸附水特性及持水模型研究显示文摘采用不同浓度离子固化剂对天然钙蒙脱土进行改性处理,开展素土与改性土在相对湿度(P/P0)0.01~0.95区间的水汽等温吸—脱附试验,通过持水速率曲线、晶层d001演化曲线及红外光谱特征峰解析蒙脱土吸附水进程中主控因素的演化规律,据此提出水合状态变化的界限相对湿度区间,在此基础上,分别从阳离子水化能和晶层表面水合能角度,建立了离子固化剂改性蒙脱土微观持水方程。试验结果表明:对于钙蒙脱土,在0 200 MPa),蒙脱土持水能力只受控于层间阳离子水化作用,而在中高吸力段(15 MPa<ψ<200 MPa),晶层基面与水之间的分子作用力是影响蒙脱土表面水合能及持水性状的主要因素。在特定吸力范围内,离子固化剂通过改变相应的物化性质参数(阳离子交换量、比表面积)从而弱化蒙脱土持水能力。基于微观水合机制所构建的持水方程能够很好预测本次试验及文献报道的数据结果,不同吸力段的持水模型可量化表征离子固化剂对蒙脱土吸附水性状的调控机理。 | 黄伟 刘清秉 项伟 张云龙 王臻华 DAO Minh Huan | 2019 | 岩土工程学报2019，41，1： | 8 |
| 10 | Mining spatiotemporal patterns of urban dwellers from taxi trajectory data显示文摘随 locationaware 技术的普遍采纳,获得个人的长顺序、巨大、高精确性的空间与时间的轨道数据在各种各样的地理研究变得日益普及。出租车的轨道数据,大多数之一广泛地使用了内部城市的旅行模式,关于两道路网络交通和旅客的旅行行为包含富有的信息。如此的数据能被用来象城市的空间结构的宏系统一样学习个人的显微镜的活动模式。这份报纸在为采矿从使 GPS 能的出租车和他们的应用获得的轨道上集中城市的变换模式。一条新奇途径被建议与很多点地点从出租车轨道数据集发现家庭旅行的空间与时间的模式。途径包含三关键步:,识别从 OD 的统计的阀值价值发现潜在地有意义的地方的基于城市的交通格子的出租车起源目的地( OD )的空间聚类聚类提取城市的工作住房结构,并且分析结果到的可视化理解空间分发和揭示城市的结构和暗示家庭变换行为的时间的趋势。有在上海的出租车轨道数据集的案例研究,中国被介绍表明并且评估建议方法。 | FengMAO Minhe JI Ting LIU | 2016 | Frontiers of Earth Science2016，10，2： | 7 |
| 11 | On the chemo-thermo-hydro-mechanical behaviour of geological and engineered barriers显示文摘An overview of the recent findings about the chemo-hydro-mechanical behaviour of materials used for both geological and engineered barriers in nuclear waste disposal is presented, through some examples about the natural Boom Clay (BC) and compacted bentonite-based materials. For the natural BC, it was found that compression index identified from both oedometer and isotropic compression tests is similar and the compressibility of BC from the Mol site is higher than that of BC from the Essen site; the shear strength of Mol BC is also higher than that of the Essen BC, suggesting a significant effect of carbonates content; the thermal volume change is strongly overconsolidation ratio (OCR) dependent-low OCR values promote thermal contraction while high OCR values favour thermal dilation; the volume change behaviour is also strongly time dependent and this time dependent behaviour is governed by the stress level and temperature; the effect of pore-water salinity on the volume change behaviour can be significant when the smectite content is relatively high. For the bentonite-based materials, it was found that thermal contraction also occurs at low OCR values, but this is suction dependent-suction promotes thermal dilation. Under constant volume conditions, wetting results in a decrease of hydraulic conductivity, followed by an increase. This is found to be related to changes in macro-pores size-wetting induces a decrease of macro-pores size, followed by an increase due to the aggregates fissuring. The presence of technological voids can increase the hydraulic conductivity but does not influence the swelling pressure. | Yu-Jun Cui Anh Minh Tang | 2013 | Journal of Rock Mechanics and Geotechnical Engineering2013，5，3： | 6 |
| 12 | 蒙脱土改性杨木板材的工艺研究Ⅰ:浸渍改性处理工艺显示文摘采用纳米蒙脱土浸渍改性普通杨木板材,提高板材的密度、力学性能以及尺寸稳定性。试验结果表明,改性处理后板材的密度、尺寸稳定性和各项力学性能都得到了显著提高,最佳改性工艺条件为:预压缩率为30%、预压温度为70℃、浸渍液浓度为4%、浸渍时间为120 min。蒙脱土不仅均匀分布于杨木内部,还与木材组分发生交联反应。与杨木素材比,处理材的刚度增加了10.92%,热稳定性能也得到显著提高。纳米蒙脱土改性处理杨木板材为地板行业提供了良好的新型材料,扩大速生低质杨木材料的使用范围。 | 范祥林 王新洲 邓玉和 蒋姗姗 CAO QUOC AN 董葛平 TRAN MINH TOI | 2016 | 中南林业科技大学学报2016，36，4： | 6 |
| 13 | Relationship between microvessel density and telomerase activity in hepatocellular carcinoma显示文摘AIM: To study the relationship between microvessel density(MVD), telomerase activity and biological characteristics in hepatocellular carcinoma (HCC).METHODS: S-P immunohistochemical method and telomeric repeat amplification protocol (TRAP) were respectively used to analyze the MVD and telomerase activity in 58 HCC and adjacent normal tissues.RESULTS: The MVD in HCC with metastasis, lower differentiation or without intact capsule was significantly higher than that in HCC with intact capsule, higher differentiation, or without metastasis. While MVD had no relationship with tumor size, hepatic virus infection and other clinical factors. Telomerase activity was related to differentiation degree, but not to tumor size or histological grade. MVD in HCC with telomerase activity was higher than that in HCC without telomerase activity.CONCLUSION: MVD and telomerase activity may serve as diagnostic criteria of HCC in earlier stage. Meanwhile,there may be a cooperative effect between MVD and telomerase on the growth and metastasis of HCC. | Yun-FengPiao MinHe YangShi Tong-YuTang | 2004 | World Journal of Gastroenterology2004，10，14： | 5 |
| 14 | Occurrence of emerging flame retardants from e-waste recycling activities in the northern part of Vietnam显示文摘This study investigated the contamination status of 21 emerging flame retardants(FRs)in soils(n=32)and river sediments(n=8)from an e-waste recycling(EWR)site in the northern part of Vietnam.Among analyzed FRs,higher levels of decabromodiphenyl ethane(DBDPE)(NDe4200 ng/g dw),1,2-bis-(2,4,6-tribromophenoxy)ethane(BTBPE)(NDe350 ng/g dw)and Dechlorane Plus isomers(DPs)(NDe65 ng/g dw)were found in soils near EWR workshops and open burning places.The highest concentrations of DBDPE(20 ng/g dw),BTBPE(5.7 ng/g dw)and DPs(6.7 ng/g dw)were also detected in sediments collected from the middle of the EWR site.The levels decreased concomitantly with increasing distance from the EWR site.These results indicate that these FRs were released to the surrounding environment from improper recycling activities,such as manual dismantling of devices and open burning of e-wastes.Moreover,the estimated daily intakes of those FRs via soil ingestion were approximately ten times higher for children than adults.To our knowledge,this is a first comprehensive study on characterization of soil and sediment contamination by a series of emerging FRs at an EWR site in Vietnam. | Masayuki Someya Go Suzuki Alin C.Ionas Nguyen Minh Tue Fuchao Xu Hidenori Matsukami Adrian Covaci Le Huu Tuyen Pham Hung Viet Shin Takahashi Shinsuke Tanabe Hidetaka Takigami | 2016 | Emerging Contaminants2016，2，2： | 5 |
| 15 | Numerical investigation of aerodynamic flow actuation produced by surface plasma actuator on 2D oscillating airfoil显示文摘Numerical simulation of unsteady flow control over an oscillating NACA0012 airfoil is investigated. Flow actuation of a turbulent flow over the airfoil is provided by low current DC surface glow discharge plasma actuator which is analytically modeled as an ion pressure force produced in the cathode sheath region. The modeled plasma actuator has an induced pressure force of about 2 k Pa under a typical experiment condition and is placed on the airfoil surface at 0% chord length and/or at 10% chord length. The plasma actuator at deep-stall angles(from 5° to 25°) is able to slightly delay a dynamic stall and to weaken a pressure fluctuation in down-stroke motion. As a result, the wake region is reduced. The actuation effect varies with different plasma pulse frequencies, actuator locations and reduced frequencies. A lift coefficient can increase up to 70% by a selective operation of the plasma actuator with various plasma frequencies and locations as the angle of attack changes. Active flow control which is a key advantageous feature of the plasma actuator reveals that a dynamic stall phenomenon can be controlled by the surface plasma actuator with less power consumption if a careful control scheme of the plasma actuator is employed with the optimized plasma pulse frequency and actuator location corresponding to a dynamic change in reduced frequency. | Minh Khang Phan Jichul Shin | 2016 | Chinese Journal of Aeronautics2016，29，4： | 5 |
| 16 | Analysis of monomeric and oligomeric organophosphorus flame retardants in fish muscle tissues using liquid chromatographyeelectrospray ionization tandem mass spectrometry:Application to Nile tilapia(Oreochromis niloticus)from an e-waste processing area in northern Vietnam显示文摘Using electrospray ionization tandem mass spectrometry combined with liquid chromatography(LC),a novel analytical method was developed to quantify eight monomeric organophosphorus flame retardants(m-PFRs)and three oligomeric organophosphorus flame retardants(o-PFRs)in fish muscle samples.The optimization and validation experiments indicate that the developed method can determine accurately the concentrations of analytes in fish muscle samples.The recoveries of analytes in fish muscle samples were in the range of 74-105%.The coefficients of variation of the concentrations of analytes in fish muscle samples were 0.6-8.9%.The concentrations of analytes in procedural blanks were below the limit of quantification(LOQ)values.Furthermore,the developed method was applied to the analysis of m-PFRs and o-PFRs in the muscle samples of tilapias collected from an electronic waste(ewaste)processing area in northern Vietnam.The concentrations of m-PFRs such as tris(2-chloroethyl)phosphate(TCEP),tris(2-chloroisopropyl)phosphate(TCIPP),and triphenyl phosphate(TPHP)were dominant among the investigated m-PFRs.The respective concentrations of TCEP,TCIPP,and TPHP were up to 160,300,and 230 ng g^-1 lipid weight,respectively,whereas those of o-PFRs were up to 10 ng g^-1 lipid weight.The results of this study indicate lower accumulation potential of o-PFRs compared with m-PFRs for the first time. | Hidenori Matsukami Go Suzuki Nguyen Minh Tue Le Huu Tuyen Pham Hung Viet Shin Takahashi Shinsuke Tanabe Hidetaka Takigami | 2016 | Emerging Contaminants2016，2，2： | 5 |
| 17 | Evolution of endoscopic extraperitoneal radical prostatectomy (EERPE): technique and outcome显示文摘内视镜的 extraperitoneal 激进分子前列腺切除术(EERPE ) 是为与局部性的前列腺癌症对待病人的一种生长得很好、标准化的技术。不过,过程连续地与解剖知识的扩大正在被精制。没有以力量,克制和 oncological 管理牺牲过程的确定的好处,在当前使用的设备的一条神经圆材途径和改进的发展被期望在 cosmesis 和康复产出更好的结果。在这研究,这种技术和它的进化详细被介绍,与它的临床的功效的分析一起。我们也请教文学把 EERPE 比作 transperitoneal laparoscopic 激进分子前列腺切除术,并且我们也在 EERPE 期间关于机器的帮助的使用讨论新技术前进。 | Jens-Uwe Stolzenburg Odysseas Andrikopoulos Panagiotis Kallidonis Iason Kyriazis Minh Do Evangelos Liatsikos | 2012 | Asian Journal of Andrology2012，14，2： | 5 |
| 18 | Synthesis and characterization of NaYF4:Yb3+,Er3+@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cells显示文摘Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer cells.These nanophosphors absorb long-wavelength excitation radiation in the infrared or near infrared region and emit shorter wavelength,higher energy radiation from ultraviolet to infrared.In this paper,we studied the hydrothermal method and optical properties of the functionalized NaYF4:Yb^3+,Er^3+for biomedical application.After synthesis,these NaYF4:Yb^3+,Er^3+nanophosphors were functionalized with aminosilanes and folic acid.Folic acid binds to the folate receptor on the surface of MCF-7 breast cancer cells and this binding promotes internalization of the nanophosphors via endocytosis.The sizes of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA(folic acid)nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 nm.Phase structure of NaYF4:Yb^3+,Er^3+is in hexagonal crystal system.The photo luminescence(PL)spectra of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA nanophosphors were measured.These nanophosphors emit in red color with the strongest band at 650 nm under 980 nm excitation.This result can provide NaYF4:Er^3+,Yb^3+@silica-N=FA complex for developing fluorescence label and image tool in cancer biology and medicine. | Ha Thi Phuong Tran Thu Huong Le Thi Vinh Hoang Thi Khuyen Do Thi Thao Nguyen Thanh Huong Pham Thi Lien Le Quoc Minh | 2019 | Journal of Rare Earths2019，37，11： | 5 |
| 19 | Seasonal and geographical distribution of bacillary dysentery(shigellosis)and associated climate risk factors in Kon Tum Province in Vietnam from 1999 to 2013显示文摘Background:Bacillary dysentery(BD)is an acute bacterial infection of the intestine caused by Shigella spp.,with clinical symptoms ranging from fever to bloody diarrhoea to abdominal cramps to tenesmus.In Vietnam,enteric bacterial pathogens are an important cause of diarrhoea and most cases in children under 5 years of age are due to Shigella strains.The serogroups S.flexneri and S.sonnei are considered to be the most common.The main objective of this study was to,for the first time,assess the seasonal patterns and geographic distribution of BD in Vietnam,and to determine the climate risk factors associated with the incidence of BD in Kon Tum Province,where the highest rate of bacillary dysentery was observed from 1999 to 2013.Methods:The seasonal patterns and geographic distribution of BD was assessed in Vietnam using a seasonaltrend decomposition procedure based on loess.In addition,negative binomial regression models were used to determine the climate risk factors associated with the incidence of BD in Kon Tum Province,from 1999 to 2013.Results:Overall,incidence rates of BD have slightly decreased over time(except for an extremely high incidence in 2012 in the north of Vietnam).The central regions(north/south central coast and central highlands)had relatively high incidence rates,whereas the northwest/east and Red River Delta regions had low incidence rates.Overall,seasonal plots showed a high peak in the mid-rainy reason and a second smaller peak in the early or late rainy season.The incidence rates significantly increased between May and October(“wet season”)across the country.In Kon Tum Province,temperature,humidity,and precipitation were found to be positively associated with the incidence of BD.Conclusions:Our findings provide insights into the seasonal patterns and geographic distribution of BD in Vietnam and its associated climate risk factors in Kon Tum Province.This study may help clinicians and the general public to better understand the timings of outbreaks and therefore equip them with the knowledge to plan better interventions(such as improving water,sanitation,and hygiene conditions)during peak seasons.This can,in turn,prevent or reduce outbreaks and onwards transmission during an outbreak. | Hu Suk Lee TTHa Hoang Phuc Pham-Duc Mihye Lee Delia Grace Dac Cam Phung Vu Minh Thuc Hung Nguyen-Viet | 2017 | Infectious Diseases of Poverty2017，6，1： | 5 |
| 20 | 基于隧道爆破设计模型的光面爆破参数显示文摘光面爆破效果高度依赖炮孔直径、岩石普氏系数、隧道断面和裂隙与隧道轮廓之间的间距等初始爆破参数。本文提出一种能够实现Delphi程序语言与AutoCAD对接的算法,基于提出的算法开发了一种隧道爆破设计模型。该隧道爆破设计模型能够实现以AutoCAD为平台的隧道光面爆破自动设计。在炮孔直径和隧道断面变化的条件下,研究了岩石普氏系数和裂隙间距对炮孔数量和单位炸药消耗量的影响,给出了一组高度相关方程。研究结果表明,单位炸药消耗量随着岩石普氏系数、裂隙间距和炮孔直径的增加而增加,但是随着隧道断面积的增加而减小。此外,炮孔数量随着隧道断面积的增加呈线性增加,但是随着炮孔直径的增大而减小。 | Nguyen Ngoc MINH 曹平 刘智振 | 2021 | Journal of Central South University2021，28，1： | 5 |
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