|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘 | Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ | 2006 | 中国神经肿瘤杂志2006,4,1: | 17 |
| 2 | Liver expression of steroid hormones and Apolipoprotein D receptors in hepatocellular carcinoma显示文摘AIM: To evaluate the tissular expression of Androgen (A), Estrogen (E) and Progesterone (Pg) receptors, and Apolipoprotein D (ApoD), in liver tumors from resected hepatocellular carcinoma (HCC) cases in order to assess their possible relationship to prognosis. METHODS: We performed an immunohistochemical study using tissue microarrays (containing more than 260 cancer specimens, from 31 HCC patients and controls) to determine the presence of specif ic antibodies against AR, ER, PgR and ApoD, correlating their findings with several clinico-pathological and biological variables. The staining results were categorized using a semi-quantitive score based on their intensity, and the percentage of immunostained cells was measured. RESULTS: A total of 21 liver tumors (67.7%) were positive for AR; 16 (51.6%) for ER; 26 (83.9%) for PgR and 12 (38.7%) stained for ApoD. We have found a wide variability in the immunostaining score values for each protein, with a median (range) of 11.5 (11.5-229.5) for AR; 11.1 (8.5-65) for ER; 14.2 (4-61) for PgR; and 37.7 (13.8-81.1) for ApoD. A history of heavy ethanol consumption, correlated positively with AR and PgR and negatively with ER status. HCV chronic infection also correlated positively with AR and PgR status. However, the presence of ApoD immunostaining did not correlate with any of these variables. Tumors with a positive immuno-staining for PgR showed a better prognosis. CONCLUSION: Our results indicate a moderate clinical value of the steroid receptor status in HCC, emphasizing the need to perform further studies in order to evaluate the possible role of new hormonal-based therapies. | FJ Vizoso M Rodriguez A Altadill ML González-Diéguez A Linares LO González S Junquera F Fresno-Forcelledo MD Corte L Rodrigo | 2007 | World Journal of Gastroenterology2007,13,23: | 11 |
| 3 | Fabrication of Bi_2O_3/TiO_2nanocomposites and their applications to the degradation of pollutants in air and water under visible-light显示文摘A nanoheterojunction composite photocatalyst Bi2O3/TiO2working under visible-light(λ 420 nm) was prepared by combining two semiconductors Bi2O3 and TiO2 varying the Bi2O3/TiO2molar ratio. Maleic acid was employed as an organic binder to unite Bi2O3 and TiO2 nanoparticles. The SEM, TEM, XRD and diffuse reflectance spectra were utilized to characterize the prepared Bi2O3/TiO2nanoheterojunction. The nanocomposite exhibited unusual high photocatalytic activity in decomposing 2-propanol in gas phase and phenol in aqueous phase and, evolution of CO2 under visible light irradiation while the end members exhibited low photocatalytic activity. The composite was optimized to 5 mol% Bi2O3/TiO2. The remarkable high photocatalytic efficiency originates from the unique relative energy band position of Bi2O3 and TiO2 as well as the absorption of visible light by Bi2O3. | Ashok Kumar Chakraborty Md Emran Hossain Md Masudur Rhaman K M A Sobahan | 2014 | Journal of Environmental Sciences2014,26,2: | 7 |
| 4 | Efficient Algorithm for Prolonging Network Lifetime of Wireless Sensor Networks显示文摘One of the fundamental design challenges in designing a Wireless Sensor Network (WSN) is to maximize the network lifetime,as each sensor node of the network is equipped with a limited power battery.To overcome this challenge,different methods were developed in the last few years using such techniques as network protocols,data fusion algorithms using low power,energy efficient routing,and locating optimal sink position.This paper focuses on finding the optimal sink position.Relay nodes are introduced in conjunction with the sensor nodes to mitigate network geometric deficiencies since in most other approaches the sensor nodes close to the sink become heavily involved in data forwarding and,thus,their batteries are quickly depleted.A Particle Swarm Optimization (PSO) based algorithm is used to locate the optimal sink position with respect to those relay nodes to make the network more energy efficient.The relay nodes communicate with the sink instead of the sensor nodes.Tests show that this approach can save at least 40% of the energy and prolong the network lifetime. | Md Nafees Rahman M A Matin | 2011 | Tsinghua Science and Technology2011,16,6: | 6 |
| 5 | Source identification, contamination status and health risk assessment of heavy metals from road dusts in Dhaka, Bangladesh显示文摘In this study, concentrations of Cr, Mn, Ni, Cu, Zn, Cd and Pb were determined in road dusts collected from different locations in Dhaka to assess source, contamination status and health risk. Energy-dispersive X-ray fluorescence spectroscopy and energy-dispersive X-ray spectroscopy were used to determine Cr, Mn, Ni, Cu, Zn, Cd and Pb and their mean concentrations were 162.27 ± 29.46, 721.18 ± 180.14, 35.65 ± 12.55, 104.56 ± 128.33, 515.32 ± 321.90,BDL, and 342.82 ± 591.20 mg/kg, respectively. Among the heavy metals, highest concentrations of Cu, Zn and Pb were found at urban sites-7(municipal waste dumping) and 8(medical waste incineration). Highest concentration of Cr followed by Cu and Zn was found at site-5(Tejgaon, urban). Principal component analysis revealed that anthropogenic activities are the potential sources for Cr, Ni, Cu, Zn and Pb while earth crust for Mn. Pollution index and pollution load index results suggested that all the sites were contaminated and/or degraded by Cr, Cu, Zn and Pb except sites-9(urban), 10(sub-urban), 11(rural) while sites-7 and 8(urban) were extremely degraded. For noncarcinogenic health risk, hazard quotient values for dermal were higher compared to that of inhalation/ingestion. Though hazard index values were less than 1 at all the sites, these were at least one order of magnitude higher for children group than that of adult group, thus the children group may face more noncarcinogenic health risk at sites -7 and 8. Values of incremental lifetime cancer risk were from 10to 10showed no carcinogenic health risk by road dusts contaminated with the heavy metals. | Aklima Nargis Ahsan Habib Md Nazrul Islam Kai Chen Md Shafiqul Islam Sarker A N M Al-Razee Wenbin Liu Guorui Liu Minggang Cai | 2022 | Journal of Environmental Sciences2022,34,11: | 3 |
| 6 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009,7,4: | 3 |
| 7 | Periareolar skinsparing mastectomy and latissimus dorsi flap with biodimensional expander implant reconstruction : surgical planning, outcome, and Complications 显示文摘 | Alexandre M Monhoz MD Claudia A | 2007 | Plast Recanstr Surg2007,119,6: | 1 |
| 8 | Coronary side-effect potential of current and prospective antimigraine drugs 显示文摘 | Reekers M Bax WA Ferrari MD | 1998 | Circulation1998,98,1: | 1 |
| 9 | Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits显示文摘 | Quiles JL Mesa MD Ramírez-Tortosa CL Aguilera CM Battino M Gil A | 2002 | Arterioscler Thromb Vasc Biol2002,22,7: | 1 |
| 10 | Gestational diabetes mellitus and lesser degrees of preg- nancy hyperglycemia : association with increased risk of spontaneous preterm birth 显示文摘 | Monique M Hedderson MPH Assiamira Ferrara MD PhD David A Sacks MD | 2003 | Obstetrics & Gynecology2003,102,: | 1 |
| 11 | Image-detected breast cancer: state of the art diagnosis and treatment 显示文摘 | Silverstein M J Lagios MD Recht A | 2005 | J Am Coll Surg2005,201,4: | 1 |
| 12 | The diagnostic role of procalcitonin and other bionmarkers in discriminating infectious from non-infectious fever 显示文摘 | Limper M de Kruif MD Duits A J | 2010 | J Infect2010,60,6: | 1 |
| 13 | Pharmacologicalprofiles of opioid ligands at Kappa opioid receptors显示文摘 | Parha M Ezzat H Timothy MD et a 1 | 2006 | BMCPharmacol2006,95,6: | 1 |
| 14 | Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus显示文摘 | Cervantes M Gonzalez-Vidal MD Ruelas R Escobar A Morali G | 2002 | Arch Med Res2002,33,: | 1 |
| 15 | Delirium in elderly patients:Evalution and management 显示文摘 | Rumman MD Jonathan M | 1995 | Mayo Clin Proc1995,70,2: | 1 |
| 16 | Pain scores improve analgesic administration patterns for trauma patients in the emergency depart- ment 显示文摘 | Paul A Silka MD Mendel M | 2004 | Academic Emergency Medicine2004,11,3: | 1 |
| 17 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011,58,18: | 1 |
| 18 | Autotrophic nitrite removal in the cathode of microbial fuel cells 显示文摘 | Puiga S Serraa M Vilar-Sanzb A Cabr6a M Bafierasb L Colprima J Balaguer MD | 2011 | Bioresour Teehnol2011,102,6: | 1 |
| 19 | The novel apolipoprotein A5 is present in human serum,is associated with VLDL,HDL,and chylomicrons,and circulates at very low concentrations compared with other apolipoproteins显示文摘 | O'Brien PJ Alborn WE Sloan JH Ulmer M Boodhoo A Knieman MD | 2005 | Clin Chem2005,51,2: | 1 |
| 20 | Primary blast traumatic brain in- jury in the rat: relating diffusion tensor imaging and behavior 显示文摘 | Budde MD Shah A McCrea M | 2013 | Front Neurol2013,14,4: | 1 |