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| 1 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 2 | Broadband tissue-equivalent phantom for BAN applications at millimeter wavesm 显示文摘 | Nacer C Maxim Z Ronan S | 2012 | IEEE Transactions on Microwave Theory and Techniques2012，60，7： | 1 |
| 3 | The Ability of Stroke Volume Variations Obtained with Vigileo/FloTrac System to Monitor Fluid Responsiveness in Mechanically Ventilated Patients显示文摘 | Maxime Cannesson Henri Musard Olivier Desebbe Cécile Boucau Rémi Simon Roland Hénaine Jean-Jacques Lehot | 2009 | Anesthesia & Analgesia2009，，2： | 1 |
| 4 | 难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。 | Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) | 2019 | 英国医学杂志中文版2019，22，2： | 1 |
| 5 | Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking 显示文摘 | Maxime D H Camilla L C Philippe R | 2003 | Science2003，302，： | 1 |
| 6 | Velocity vector imag- ing to quantify ventricular dyssynchrony and predict response to cardiac resynchronization therapy显示文摘 | Maxime C Masaki TD Matthew S | 2006 | Am J Cardiol2006，98，7： | 1 |
| 7 | Constraints on the acquisition of remanent magnetization in fine-grained sediments imposed by redeposition experiments显示文摘 | BRIAN C S JEAN P V MAXIME L G | 2006 | Earth and Planetary Science Letters2006，245，： | 1 |
| 8 | Multidisciplinary prac- tical guidelines for gastrointestinal access for enteral nutrition and decompression from the Society of Interventional Radiology and American Gastroenterological Association ( AGA ) Institute, with endorsement by Canadian Interventional Radiological Association (CIRA) and Cardiovascular and Interventional Radiological Socie- ty of Europe(CIRSE) 显示文摘 | MAXIM I MARK H D JOHN C F | 2011 | J Vasc Interv Radiol2011，22，8： | 1 |
| 9 | Circulatory and respiratory effects of an hypoxic stress in the Siberian sturgeon respiration physiology 显示文摘 | Maxime V Nonnotte G Peyraud C | 1995 | Respiration Physiology1995，100，3： | 1 |
| 10 | Changes of opening angle in hypertensive and hypotensive arteries in 3-day organ culture 显示文摘 | Han H C Maxim S Ku D N | 2006 | J Biomeeh2006，39，13： | 1 |
| 11 | Excess neutrophil infi hration during cytomegalovirus brain infection of interleukin-lO-deficient mice 显示文摘 | Manohar B M Maxim C J Hu S | 2010 | J Neuroimmunol2010，227，12： | 1 |
| 12 | Parental and self-report of sleep in children with attention-deficit/hyperactivity disorder显示文摘 | Owens JA Maxim R Nobile C | 2000 | Arch Pediatr Adolesc Med2000，154，6： | 1 |
| 13 | Analysis of convergent evidence in an evidential reasoning knowledge-based classification显示文摘 | Yafit C Maxim S | 2005 | Remote Sensing of Environment2005，96，34： | 1 |
| 14 | Construc- ting robust channel structures by packing metallacalix- arenes: reversible single-crystal-to-single-crystal dehy- dration显示文摘 | EEN C D MADALAN A M MAXIM C | 2009 | J Am Chem Soc2009，131，13： | 1 |
| 15 | The hand of the DLR hand arm system:Designed for interaction显示文摘 | MARKUS G MAXIME C WEMER F | | 0，，13： | 1 |
| 16 | Circulatory and respira- tory effects of an hypoxic stress in the Siberian sturgeon respira- tion physiology 显示文摘 | Maxime V Nonnotte G Peyraud C | 1995 | Respiration Physiology1995，100，3： | 1 |
| 17 | Parental and self-report of sleep in children with attention - deficit/hyperactivity disorder 显示文摘 | Owens JA Maxim R Nobile C | 2000 | Arch Pediatr Adolesc Med2000，154，6： | 1 |
| 18 | Velocity vector imaging to quantify ventricular dyssynchrony and predict response to cardiac resynchronization therapy显示文摘 | Maxime C Masaki TD Matthew S | 2006 | Am J Cardiol2006，98，7： | 1 |
| 19 | Decentralised plan- ning coordination with quantity discount contract in a divergent supply chain显示文摘 | Maxime O van Dat C Julien B | 2013 | International Journal of Produc- tion Research2013，51，9： | 1 |
| 20 | TrkB inhibition as a therapeutic target for CNS-related disorders显示文摘 | Fabien B Gunter K Maxime C | | 0，，02： | 1 |
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