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| 1 | Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection显示文摘AIM:To characterize the impact of the Pringle ma-neuver (PM) and ischemic preconditioning (IP) on total blood supply to the liver following hepatectomies. METHODS: Sixty one consecutive patients who un-derwent hepatic resection under in flow occlusion were randomized either to receive PM alone (n = 31) or IP (10 min of ischemia followed by 10 min of reperfusion) prior to PM (n = 30). Quantification of liver perfusion was measured by Doppler probes at the hepatic artery and portal vein at various time points after reperfusion of remnant livers. RESULTS: Occlusion times of 33 ± 12 min (mean ± SD) and 34 ± 14 min and the extent of resected liver tissue (2.7 segments) were similar in both groups. In controls (PM), on reperfusion of liver remnants for 15 min, portal perfusion markedly decreased by 29% while there was a slight increase of 8% in the arterial blood flow. In contrast, following IP + PM the portal vein flow remained unchanged during reperfusion and a significantly increased arterial blood flow (+56% vs baseline) was observed. In accordance with a better postischemic blood supply of the liver, hepatocellular injury, as measured by alanine aminotransferase (ALT) levels on day 1 was considerably lower in group B compared to group A (247 ± 210 U/I vs 550 ± 650 U/I, P < 0.05). Additionally, ALT levels were significantly correlated to the hepatic artery in flow.CONCLUSION: IP prevents postischemic flow reduction of the portal vein and simultaneously increases arterial perfusion, suggesting that improved hepatic macrocirculation is a protective mechanism following hepatectomy. | Oleg Heizmann Georgios Meimarakis Andreas Volk Daniel Matz Daniel Oertli Rolf J Schauer | 2010 | World Journal of Gastroenterology2010，16，15： | 12 |
| 2 | Impact of violaceinproducing bacteria on survival and feeding of bacterivorous nanoflagellates显示文摘 | Matz C Deines P Boenigk J | 2004 | Appl Environ Microbiol2004，70，： | 1 |
| 3 | Omalizumab provides long-term control in patients with moderate-to-severe allergic asthma显示文摘 | Buhl R Soler M Matz J | 2002 | Eur Respir J2002，20，1： | 1 |
| 4 | Impact of violaceinproducing bacteria on survival and feeding of bacterivorous nanoflagellates显示文摘 | Matz C Deines P Boenigk J | | 0，，03： | 1 |
| 5 | The anti IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics显示文摘 | Soler M Matz J Townley R | 2001 | Eur Respire J2001，18，2： | 1 |
| 6 | Accumulation and elimination of cadmium in larval stage zebrafish following acute ex- posure显示文摘 | Matz C J Treble R G Krone P H | 2007 | Ecotoxicology and environmental safety2007，66，1： | 1 |
| 7 | Montelukast for chronic asthma in 6 to 14-year-old children:A randomized,double-blind trial显示文摘 | Knorr B Matz J Bemstein J | | 0，，15： | 1 |
| 8 | Symptom exacerbation in tourette syndrome due to bacterial reinfection 显示文摘 | Dehning S Matz J Riedel M | 2009 | J Clin Psychiatry2009，70，11： | 1 |
| 9 | Two putative protein export regulators promote Plasmodium blood stage develop- ment in vivo显示文摘 | Matz J M Matuschewski K Kooij T W | 2013 | Mol Biochem Parasitol2013，191，1： | 1 |
| 10 | Working conditions of female part-time and full-time teachers in relation to health status 显示文摘 | Seibt R Matz A Hegewald J | 2012 | Int Arch Oceup Environ Health2012，85，6： | 1 |
| 11 | Cell death after exposure to subarachnoid hemolysate correlates inversely with expression of CuZn-superoxide dismutase 显示文摘 | Matz P G Copin J C Chan P H | 2000 | Stroke2000，31，10： | 1 |
| 12 | Omalizumab provides long-term control in patients with moderate-to-severe allergic asthma显示文摘 | Buhl R Matz J Townleyz R | 2002 | Eur Respir J2002，20，1： | 1 |
| 13 | Carbide formation in alloy 718 during electron-beam solid freeform fabrication显示文摘 | Matz J E Eagar T W | 2002 | Metallurgical and Materials Transactions A:Physical Metallurgy and Materials Science2002，33，8： | 1 |
| 14 | Guidance,navigation, and control system performance trades for Mars pinpointlanding显示文摘 | Steinfeldt B A Grant M J Matz D A | 2010 | Journal of Spacecraft & Rockets2010，47，18： | 1 |
| 15 | Tne antiIgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics显示文摘 | Soler M Matz J Townley R | 2001 | Eur Respir J2001，18，2： | 1 |
| 16 | The anti - IgE antibody omalizumab improves asthma- related quality of life in patients with allergic asthma显示文摘 | Buhl R Soler M Matz J | 2002 | Eur Respir J2002，20，5： | 1 |
| 17 | A nonlinear image contrast sharpening approach based on Munsell's scale显示文摘 | Matz S C de Figueiredo R J P | 2006 | IEEE Trans Image Process2006，15，4： | 1 |
| 18 | The anti-IgE antibody Omal-izumab improves asthma-related quality of life in patients with aller-gic asthma显示文摘 | BUHL R SOLER M MATZ J | 2002 | Eur Respir J2002，20，1： | 1 |
| 19 | A comparison of fluticasone propionate nasal spray and cetirizine in ragweed fall seasonal allergic rhinitis显示文摘 | Ford LB Matz J Hankinson T Prillaman B | 2015 | Allergy Asthma Proc2015，36，4： | 1 |
| 20 | Guidance, navigation, and control system performance trades for Mars pinpoint landing显示文摘 | Steinfeldt B A Grant M J Matz Daniel A | 2010 | Journal of Spacecraft and Rockets2010，47，1： | 1 |
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