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| 1 | 非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。 | R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 | 1998 | 英国医学杂志中文版1998，0，3： | 11 |
| 2 | Porous chitosan scaffolds for tissue engineering显示文摘 | Madihally S V Matthew H W T | | 0，，： | 2 |
| 3 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 4 | Evaluation of the biocompatibility of a chitosan scaffold in mice显示文摘 | vander Vord P J Matthew H W DeSilva S P et aI | 2002 | Biomed Mater Res2002，59，3： | 1 |
| 5 | Application of chitosanbased polysaccharide biomaterials in cartilage tissue engineering: A review显示文摘 | Francis Suh J K Matthew H W T | 2000 | Biomaterials2000，21，24： | 1 |
| 6 | Precompetitiveanxiety in sport:The contribution of achievement goal-sand perfectionism显示文摘 | Hall H K Kerr A W Matthews J | 1998 | Psychology of Sport and Exer-cise1998，20，2： | 1 |
| 7 | Recycling Steel from Grinding Swarf 显示文摘 | Fu H Matthews M A Langdon S W | 1998 | Waste Management1998，18，5： | 1 |
| 8 | Examining the relation between ethical focus and fi-nancial performance in family firms:an exploratory study显示文摘 | O BOYLE E H MATTHEW W R POLLACK J M | | 0，，04： | 1 |
| 9 | Comparative Life- cycleAir Emissions of Coal,Domestic Natural Gas,LNG,and SNG forElectricity Generation 显示文摘 | Jaramillo P Griffin W M Matthews H S | 2007 | Environmental Science & Technology2007，41，17： | 1 |
| 10 | Anisotropic effects on the strain rate dependence of a wrought magnesium alloy 显示文摘 | MATTHEW T T MARK F H PHILLIP M G HAITHAM E K WILBURN R W | 2009 | Scripta Materialia2009，60，： | 1 |
| 11 | Precompetitive anxiety in sport: the contribution of achievement goals and perfec- tionism显示文摘 | Hall H K Kerr A W Matthews J | 1998 | Journal of Sport & Exercise Psychology1998，20，2： | 1 |
| 12 | Evaluation ofthe biocompatibility of a chitosan scaffold in mice 显示文摘 | VandeYord P J Matthew H W DeSilva S P | 2002 | BiomedMater Res2002，59，3： | 1 |
| 13 | Ultrasonically assisted synthesis and degradation of poly ( dimethyl siloxane) 显示文摘 | Gareth J P Matthew P H Emma N K W | 1996 | Polymer1996，37，12： | 1 |
| 14 | 显示文摘 | VandeVord P J Matthew H W DeSilva S P | 2002 | Journal of Biomedical Materials Research2002，59，3： | 1 |
| 15 | Changes in Neutrophil Surface Receptor expression,Degranulation,and Respiratory Burst Activity Following Moderate and High Intensity Exercise显示文摘 | Jonathan P Gary W Matthew H | | 0，，02： | 1 |
| 16 | Experimental studies in the LENS supersonic and hypersonic tunnels for hypervelocity vehicle performance and code validation 显示文摘 | Michael S H Timothy P W Matthew M | 2008 | AIAA2008，2505，： | 1 |
| 17 | Thickness effects on the mechanical properties of micro-arc discharge oxide coatings on aluminum alloys显示文摘 | Nie X Leyland A Song H W Yerokhin A L Dowey S J Matthews A | 1999 | Surface and Coatings Technology1999，，： | 1 |
| 18 | Application of chitosan-based polysaccharide biomateri',ds in cartilage tissue engineering: a review显示文摘 | Suh J K Matthew H W T | 2000 | Biomaterials2000，21，24： | 1 |
| 19 | Total hip replacement due to osteoarthritis: the importance of age, obesity, and other modifiable risk factors显示文摘 | Elizabeth W Karlson Lisa A Mandl Gideon N Aweh Oliver Sangha Matthew H Liang Francine Grodstein | 2003 | The American Journal of Medicine2003，，2： | 1 |
| 20 | Vitamin a deficiency impairs fetal islet development and causes subsequent glucose intolerance in adult rats 显示文摘 | MATTHEWS K A RHOTEN W B DRISCOLL H K | 2004 | The Journal of Nutrition2004，134，8： | 1 |
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