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| 1 | Alternatives for large-scale production of cultured beef: A review显示文摘Cultured beef is a method where stem cells from skeletal muscle of cows are cultured in vitro to gain edible muscle tissue. For large-scale production of cultured beef, the culture technique needs to become more efficient than today's 2-dimensional(2D) standard technique that was used to make the first cultured hamburger. Options for efficient large-scale production of stem cells are to culture cells on microcarriers, either in suspension or in a packed bed bioreactor, or to culture aggregated cells in suspension. We discuss the pros and cons of these systems as well as the possibilities to use the systems for tissue culture. Either of the production systems needs to be optimized to achieve an efficient production of cultured beef. It is anticipated that the optimization of large-scale cell culture as performed for other stem cells can be translated into successful protocols for bovine satellite cells resulting in resource and cost efficient cultured beef. | Matilda S M Moritz Sanne E L Verbruggen Mark J Post | 2015 | Journal of Integrative Agriculture2015，14，2： | 7 |
| 2 | Proton pump inhibitor-induced hypomagnesemia: A new challenge显示文摘Proton pump inhibitors(PPIs)are commonly used in clinical practice for the prevention and treatment of peptic ulcer,gastritis,esophagitis and gastroesophageal reflux.Hypomagnesemia has recently been recognized as a side effect of PPIs.Low magnesium levels may cause symptoms from several systems,some of which being potentially serious,such as tetany,seizures and arrhythmias.It seems that PPIs affect the gastrointestinal absorption of magnesium.Clinicians should be vigilant in order to timely consider and prevent or reverse hypomagnesemia in patients who take PPIs,especially if they are prone to this electrolyte disorder. | Matilda Florentin Moses S Elisaf | 2012 | World Journal of Nephrology2012，1，6： | 5 |
| 3 | Role of dipeptidyl peptidase 4 inhibitors in the new era of antidiabetic treatment显示文摘The last few years important changes have occurred in the field of diabetes treatment.The priority in the therapy of patients with diabetes is not glycemic control per se rather an overall management of risk factors,while individualization of glycemic target is suggested.Furthermore,regulatory authorities now require evidence of cardiovascular(CV)safety in order to approve new antidiabetic agents.The most novel drug classes,i.e.,sodium-glucose transporter 2 inhibitors(SGLT2-i)and some glucagon-like peptide-1 receptor agonists(GLP-1 RA),have been demonstrated to reduce major adverse CV events and,thus,have a prominent position in the therapeutic algorithm of hyperglycemia.In this context,the role of previously used hypoglycemic agents,including dipeptidyl peptidase 4(DPP-4)inhibitors,has been modified.DPP-4 inhibitors have a favorable safety profile,do not cause hypoglycemia or weight gain and do not require dose uptitration.Furthermore,they can be administered in patients with chronic kidney disease after dose modification and elderly patients with diabetes.Still,though,they have been undermined to a third line therapeutic choice as they have not been shown to reduce CV events as is the case with SGLT2-i and GLP-1 RA.Overall,DPP-4 inhibitors appear to have a place in the management of patients with diabetes as a safe class of oral glucose lowering agents with great experience in their use. | Matilda Florentin Michael S Kostapanos Athanasia K Papazafiropoulou | 2022 | World Journal of Diabetes2022，13，2： | 3 |
| 4 | Colonoscopy preparation-induced disorders in renal function and electrolytes显示文摘Colonoscopy and flexible sigmoidoscopy are commonly used mainly for colon cancer screening and detection, but also in several other situations such as inflammatory bowel disease (for diagnosis and follow up) and gastrointestinal hemorrhage. Bowel cleansing preparations mainly include polyethylene glycol and oral sodium phosphate solutions, with the later being most frequently used due to better toleration from patients. Despite their favourable safety profile these agents have been associated with renal function deterioration and electrolyte disorders, some of which were serious or even fatal. The present paper discusses the complications associated with colonoscopy preparation agents. | Matilda Florentin George Liamis Moses S Elisaf | 2014 | World Journal of Gastrointestinal Pharmacology and Therapeutics2014，5，2： | 2 |
| 5 | Chemical composition and microbiological changes during spontaneous and starter culture fermentation of Enam Ne-Setaakye, a West African fermented fish- carbohydrate product显示文摘 | MATILDA A ABIODUM I S | 2002 | European Food Research and Technology2002，215，1： | 1 |
| 6 | Effect of 2-deoxy-D-glucose on herpes simplex virus replication显示文摘 | RICHARD J C SHELDOM M S MATILDA B M | 1973 | Virology1973，52，： | 1 |
| 7 | Development and statistical evaluation of models in forecasting moth phenology of major lepidopterous peach pest complex for Integrated Pest Management programs 显示文摘 | PETROS T D MATILDA S S | 2010 | Crop Protection2010，29，10： | 1 |
| 8 | Chemical composition and microbiological changes during spontaneous and starter culture fermentation of Enam Ne-Setaakye, a West African fermen- ted fish-carbohydrate product显示文摘 | Matilda A Abiodun I S | 2002 | European Food Research and Technology2002，215，1： | 1 |
| 9 | Development and statistical evaluation ofmodels in forecasting moth phenology of major lepidopterous peachpest complex for Integrated Pest Management programs显示文摘 | Petros T D Matilda S S | 2010 | Crop Protection2010，29，10： | 1 |
| 10 | Development and statistical evaluation of models in forecasting moth phenology of major lepidopterous peach pest complex for Integrated Pest Management programs 显示文摘 | PETRON T D MATILDA S S | 2010 | Crop Protection2010，29，10： | 1 |
| 11 | Phosphite, an analog of phosphate, suppresses the coordinated expression of genes under phosphate starvation 显示文摘 | Varadarajan D K Karthikeyan A S Matilda P D | 2002 | Plant Physiology2002，129，3： | 1 |
| 12 | Some remarks on the stable matching problem 显示文摘 | Douglas G Matilda S | 1985 | Discrete Applied Mathematics1985，11，： | 1 |
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