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| 1 | Non-operative management of pancreatic trauma in adults显示文摘To the Editor:Pancreatic trauma accounts for 0.4%-2.0%of all trauma-related injuries worldwide[1-3].The American Association for the Surgery of Trauma(AAST)categorizes pancreatic injury according to the severity[4].Pancreatic injury involving transection of the gland(grades III to V)typically requires surgical management[4].However,pancreatic trauma,especially in children and young adults,can be managed without surgery[5].This study reports the outcome of a policy of preferential non-operative management of pancreatic trauma in adults. | Nadia Matias a Santhalingam Jegatheeswaran a Vinotha Nadarajah Aali J.Sheen Saurabh Jamdar Ajith K.Siriwardena | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，6： | 3 |
| 2 | Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences显示文摘Pre-mRNA splicing is an essential step in the process of gene expression in eukaryotes and consists of the removal ofintrons and the linking of exons to generate mature mRNAs. This is a highly regulated mechanism that allows the alternative usage of exons, the retention ofintronic sequences and the generation of exonic sequences of variable length. Most human genes undergo splicing events, and disruptions of this process have been associated with a variety of diseases, including cancer. Hepatocellular carcinoma (HCC) is a molecularly heterogeneous type of tumor that usually develops in a cirrhotic liver. Alterations in pre-mRNA splicing of some genes have been observed in liver cancer, and although still scarce, the available data suggest that splicing defects may have a role in hepatocarcinogenesis. Here we briefly review the general mechanisms that regulatepre-mRNA splicing, and discuss some examples that illustrate how this process is impaired in liver tumorigenesis, and may contribute to HCC development. We believe that a more thorough examination of pre-mRNA splicing is still needed to accurately draw the molecular portrait of liver cancer. This will surely contribute to a better understanding of the disease and to the development of new effective therapies. | Carmen Berasain Saioa Gońi Josefa Castillo Maria Ujue Latasa Jesús Prieto Matias A Avila | 2010 | World Journal of Gastroenterology2010，16，25： | 2 |
| 3 | Proteinase activity of pseudomonas fluorescens grown in cold milk supplemented with nitrogenand carbon sources显示文摘 | JASPE A PALACIOS P MATIAS P | 1994 | J Dairy Sci1994，77，： | 1 |
| 4 | Screening fort twints ransfusion syndrome at 11~ 14 weeks of pregnancy:the key role of ductus venosus blood flow assessment显示文摘 | Matias A Mon tenegro N Loureiro T | | 0，，10： | 1 |
| 5 | Anammox sludge immobilized in polyvinyl alcohol (PVA) cryogel carriers显示文摘 | Magri Albert Vanotti Matias B SzOgi Ariel A | 2012 | Biore- sour Teehnol2012，114，： | 1 |
| 6 | Control of chaos in unidimensional maps 显示文摘 | GUEMEZ J MATIAS M A | 1993 | Phys Lett1993，182，： | 1 |
| 7 | Stabilization of chaos by proportional pulses in the system variables显示文摘 | MATIAS M A GUEMEZ J | 1994 | Phys Lett1994，72，10： | 1 |
| 8 | Two members of the thioredoxin-h family interact with the kinase domain of a Brassica S-locus receptor kinase 显示文摘 | Bower M S Matias D D Femandes-carvalho E Mazzurco M Gu T Rothstein A J and Goring D R | 1996 | Plant Cell1996，8，： | 1 |
| 9 | Screening for twin-twin transfusion syndrome at 11-14 weeks of pregnancy:the key role of ductus venosus blood flow assessment显示文摘 | Matias A Montenegro N Loureiro T | | 0，，02： | 1 |
| 10 | Stablization of chaos by proportional pulses in the system variables显示文摘 | MATIAS M A GUEMEZ J | 1994 | Phys Rev Lett1994，72，： | 1 |
| 11 | Assessing the efficiency of travel agencies with a stochastic cost frontier: a Portuguese case study显示文摘 | Barros C P Matias A | 2006 | International Journal of Tourism Research2006，8，5： | 1 |
| 12 | Development of environmentally superior treatment system to replace anaerobic swine lagoons in the USA 显示文摘 | Matias B Ariel A Patrick G | 2007 | Bioresource Technology2007，98，17： | 1 |
| 13 | The positive effect of immuno- suppression on adaptation of venous allografts to arterialisation in rats 显示文摘 | Matia I Varga M Lodererova A | 2010 | Eur J Vase Endovasc Surg2010，39，4： | 1 |
| 14 | Culture of microalgae using interstitial water extracted from shrimp pond bottom sediments 显示文摘 | Yusoff F M Matias H B Khalid Z A | 2001 | Aquaculture2001，201，： | 1 |
| 15 | Crack-growth calculations in 7075-T7351 aluminum alloy under various load spectra using an improved crack-closure model显示文摘 | NEWMAN J C BROT A MATIAS C | 2004 | Engineering Fracture Mechanics2004，71，： | 1 |
| 16 | ASMase is required for chronic alcohol induced hepatic endoplasmie reticulum stress and mitochondrial cholesterol loading显示文摘 | Fernandez A Matias N Fucho tL | 2013 | JHepatol2013，59，4： | 1 |
| 17 | Microstructural and electrical properties of sintered tungsten trioxide显示文摘 | Filho S A G Matias J G N Dias N L | 1999 | Journal of Material Science1999，34，： | 1 |
| 18 | Family physician and endocrinologist coordination as the basis for diabetes care in clinical practice 显示文摘 | Duran A Runkle I Matia P | 2008 | BMC Endocr Disord2008，31，8： | 1 |
| 19 | Control of chaos in undimensional map显示文摘 | GUEMEZ J MATIAS M A | 1993 | Phys Lett A1993，181，1： | 1 |
| 20 | Assessing the efficiency of travel agen- cies with a stochastic cost frontier: a Portuguese case study 显示文摘 | Barros C P Matias A | 2006 | International Journal of Tourism Research2006，8，5： | 1 |
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