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88篇 您的检索式：作者名="Matia I"

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	题名	作者	年代	出处	被引量
1	Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences显示文摘Pre-mRNA splicing is an essential step in the process of gene expression in eukaryotes and consists of the removal ofintrons and the linking of exons to generate mature mRNAs. This is a highly regulated mechanism that allows the alternative usage of exons, the retention ofintronic sequences and the generation of exonic sequences of variable length. Most human genes undergo splicing events, and disruptions of this process have been associated with a variety of diseases, including cancer. Hepatocellular carcinoma (HCC) is a molecularly heterogeneous type of tumor that usually develops in a cirrhotic liver. Alterations in pre-mRNA splicing of some genes have been observed in liver cancer, and although still scarce, the available data suggest that splicing defects may have a role in hepatocarcinogenesis. Here we briefly review the general mechanisms that regulatepre-mRNA splicing, and discuss some examples that illustrate how this process is impaired in liver tumorigenesis, and may contribute to HCC development. We believe that a more thorough examination of pre-mRNA splicing is still needed to accurately draw the molecular portrait of liver cancer. This will surely contribute to a better understanding of the disease and to the development of new effective therapies.	Carmen Berasain Saioa Gońi Josefa Castillo Maria Ujue Latasa Jesús Prieto Matias A Avila	2010	World Journal of Gastroenterology2010，16，25：	2
2	Simultaneous measurement of strain and temperature using a fiber Bragg grating and a thermochromic material显示文摘	Fernandez-Valdivielso C Matias I R Arregui F J	2002	Sensors and Actuators A: Physical2002，101，12：	1
3	Nonadiabatic tapered single-mode fiber coated with humidity sensitive nanofilms 显示文摘	J M Corres J Bravo I R Matias	2006	IEEETechnol Lett2006，18，8：	1
4	Design of humidity sensors based on tapered optical fibers 显示文摘	CORRES J M ARREGUI F J MATIAS I R	2006	J Lightwave Technology2006，24，11：	1
5	Expression of tolerance for Meloidogyne graminicola in rice euhivars as affected by soil type and flooding显示文摘	Soriano I R S Prot J C Matias D M	2000	Journal of nematology2000，，32：	1
6	Analysis of one-dimensional photonic band gap structures with a liquid crystal defect towards development of fiber-optic tunable wavelength filters显示文摘	Villar I D Matias I R Arregui F J	2003	Optics Express2003，11，3：	1
7	Optical fiber humidity sensor using a nano Fabry-Perot cavity formed by the ionic self-assembly method显示文摘	ARREGUI F J LIU Yan-jing MATIAS I R	1999	Sens Actuators B1999，59，：	1
8	Regulation, function and dysregulation of endocannabinoids in models of adipose and β-pancreatic cells and in obesity and hyperglycemia 显示文摘	Matias I Gonthier MP Orlando P	2006	J ClinEndocrin Metab2006，91，18：	1
9	Optimization of sensitivity in long period fiber gratings with overlay deposition显示文摘	Ignacio D V Ignacio R Matias I R	2005	Optics Express2005，13，1：	1
10	Sensitivity optimization of tapered optical fiber humidity sensors by means of tuning the thickness of nanostructured sensitive coatings 显示文摘	Corres J M Arregui F J Matias I R	2007	Sensors and Actuators B2007，，122：	1
11	The positive effect of immuno- suppression on adaptation of venous allografts to arterialisation in rats 显示文摘	Matia I Varga M Lodererova A	2010	Eur J Vase Endovasc Surg2010，39，4：	1
12	Endocannabinoid control of food intake and energy balance显示文摘	Di Marzo V Matias I	2005	Nat Neurosci2005，8，：	1
13	Analysis of one dimensional photonic hand gap structures with a liquid crystal defect towards development of fiber-optic tunable wavelength filter显示文摘	VILLAR I D MATIAS I R ARREGUI F J	2003	Opt Exp2003，11，5：	1
14	Family physician and endocrinologist coordination as the basis for diabetes care in clinical practice 显示文摘	Duran A Runkle I Matia P	2008	BMC Endocr Disord2008，31，8：	1
15	Simultaneous measurement of strain and temperature using a fiber Bragg grating and a thermochromic material 显示文摘	Valdivielso Fernandez Matias I R Arregui F J	2002	Optical Fiber Sensors Conference Technical Digest2002，1，1：	1
16	Endogenous and uric Acid - Induced activation of NLRP3 inflammasome in pregnant women with preeelampsia 显示文摘	MATIAS M L ROM/~O M WEEL I C	2015	PLOS One2015，10，01：	1
17	Endocannabinoid control of food intake and energy balance 显示文摘	Di Marzo V Matias I	2005	Nat Neurosci2005，8，：	1
18	Simultaneous Measurement of Strain and Temperature Using a Fiber Bragg Grating and a Thermochromic Material显示文摘	Fernandez Valdivielso C Matias I R Arregui F J	2002	Sensors and Actuators2002，101，：	1
19	Enhancement of sensitivity in long-period fiber gratings with deposition of low-refrac- tive-index materials 显示文摘	VILLAR I D MATIAS I R ARREGUI F 1	2005	Optics Letters2005，30，23：	1
20	Dysregulation of pe- ripheral endocannabinoid levels in hyperglycemia and obesity: effect of high fat diets显示文摘	Matias I Petrosino S Racioppi A	2008	Mol Cell Endocrinol2008，286，121：	1

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