|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Glutathione (GSH) improves sperm quality and testicular morphology in streptozotocin-induced diabetic mice显示文摘Diabetes mellitus(DM)is known to cause reproductive impairment.In men,it has been linked to altered sperm quality and testicular damage.Oxidative stress(OS)plays a pivotal role in the development of DM complications.Glutathione(GSH)is a part of a nonenzymatic antioxidant defense system that protects lipid,protein,and nucleic acids from oxidative damage.However,the protective effects of exogenous GSH on the male reproductive system have not been comprehensively examined.This study determined the impact of GSH supplementation in ameliorating the adverse effect of type 1 DM on sperm quality and the seminiferous tubules of diabetic C57BL/6NTac mice.GSH at the doses of 15 mg kg^(-1)and 30 mg kg^(-1)was given intraperitoneally to mice weekly for 6 consecutive weeks.The mice were then weighed,euthanized,and had their reproductive organs excised.The diabetic(D Group)showed significant impairment of sperm quality and testicular histology compared with the nondiabetic(ND Group).Diameters of the seminiferous lumen in diabetic mice treated with 15 mg kg^(-1) GSH(DGSH15)were decreased compared with the D Group.Sperm motility was also significantly increased in the DGSH15 Group.Improvement in testicular morphology might be an early indication of the protective roles played by the exogenous GSH in protecting sperm quality from effects of untreated type 1 DM or diabetic complications.Further investigation using different doses and different routes of GSH is necessary to confirm this suggestion. | Fathiah Abdullah Mohamed Noor Khan Nor-Ashikin Renu Agarwal Yuhaniza Shafinie Kamsani Mastura Abd Malek Nor Salmah Bakar Aqila-Akmal Mohammad Kamal Mimi-Sophia Sarbandi Nor-Shahida Abdul Rahman Nurul Huda Musa | 2021 | Asian Journal of Andrology2021，23，3： | 3 |
| 2 | 炎症、癫痫发作和癫痫发生:对人类疾病的探索显示文摘癫痫在历史上被认为是一种神经元信号异常传导的疾病,表现为癫痫发作。随着大量自身抗体的发现和对自身免疫性脑炎认识的不断加深,人们越来越重视先天性和适应性免疫系统在癫痫发作和癫痫发生中的作用。在不同的癫痫发作相关的神经炎症和自身免疫疾病中,不同程度观察到了致病性抗体、补体激活、CD8+细胞毒性T细胞和小胶质细胞激活。这些异常的免疫反应被认为会导致神经元信号传导破坏,产生急性症状性癫痫发作,并且在某些情况下,还会发展为长期的自身免疫性癫痫。虽然早期使用免疫调节疗法可以改善自身免疫性脑炎和自身免疫性癫痫的预后,但患者的识别和治疗方法的选择并不总是明确。本篇综述讨论了免疫系统的不同成分在各种形式的癫痫发作中的作用,包括自身免疫性脑炎、自身免疫性癫痫、Rasmussen脑炎、热性感染相关性癫痫综合征和新发难治性癫痫持续状态。尤其是讨论了在这些疾病中观察到的病理生理学和独特的细胞因子谱,及其与诊断、预后和治疗决策的联系。 | Tan TH Perucca P O'Brien TJ Kwan P 高凡凯(译) 李硕(译) 薛国芳(审) Mastura Monif | 2022 | 癫痫杂志2022，8，4： | 2 |
| 3 | Entrepreneurship in the tourism industry Issues in developing countries显示文摘 | Mastura Jaafar Abdul Rashid Abdul Aziz | 2011 | International Journal of Hospitality Management2011，30，： | 1 |
| 4 | City Develop- ment strategies (CDS) and sustainable urbanization in develo- ping world 显示文摘 | MOSTAFA S R NURWATI B MASTURA J | 2012 | Social and Behavioral Sciences2012，，36： | 1 |
| 5 | Explo-ration sense of place for an old city district of York, Istanbul andBangkok显示文摘 | NikMohammad Nik Mastura and & Saruwono Masran | 2012 | Science Direct2012，，： | 1 |
| 6 | Modeling the Spatial Dynamics of Regional Land Use: The CLUE-S Model显示文摘 | PETER H. VERBURG WELMOED SOEPBOER A. VELDKAMP RAMIL LIMPIADA VICTORIA ESPALDON SHARIFAH S.A. MASTURA | 2002 | Environmental Management2002，，3： | 1 |
| 7 | Peripheral pulmonary arteries:How far in the long does mufti-detector row spiral CT allow analysis显示文摘 | Ghaye B Szapiru D Mastura L | 2001 | Radiology2001，219，： | 1 |
| 8 | Single-step Dyeing and Formaldehyde-Free Durable Press Finishing of Cotton Fabric显示文摘 | Mastura R Chen Guo | 1998 | T R J1998，，8： | 1 |
| 9 | Entrepreneurship in the tourism industry:Issues in developing countries显示文摘 | Mastura Jaafar | | 0，，04： | 1 |
| 10 | Modeling the Spatial Dynamics of Regional Land Use: The CLUE-S Model显示文摘 | PETER H. VERBURG WELMOED SOEPBOER A. VELDKAMP RAMIL LIMPIADA VICTORIA ESPALDON SHARIFAH S.A. MASTURA | 2002 | Environmental Management2002，，3： | 1 |
| 11 | Efflux genes and active efflux activity detection in Malaysian clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA)显示文摘 | Saiful A J Mastura M Zarizal S | | 0，，： | 1 |
| 12 | Definitive concurrent ehem,radiotherapy in cervical cancer-a University of Malaya Medical Centre experience 显示文摘 | Zamaniah WI Mastura MY Phua CE | 2014 | Asian Pace J Cancer Prev2014，15，20： | 1 |
| 13 | Prevertebral soft tissue measurements in thyroid enlargement: the value of lateral neck radiographs 显示文摘 | Hisham A N Sarojah A Mastura T | 2004 | Asian J Surg2004，27，3： | 1 |
| 14 | Entrepreneurship in the tourism industry: Issues in developing countries显示文摘 | Mastura Jaafar Abdul Rashid Abdul-Aziz Siti Aishah Maideen Siti Zaleha Mohd | 2011 | International Journal of Hospitality Management2011，，4： | 1 |
| 15 | Local Community Readiness in Entrepreneurship: Do Gender Differ in Searching Business Op- portunity显示文摘 | Norziani Dahalana & Mastura Jaafar | 2013 | Procedia-Social and Behavioral Sciences2013，，10： | 1 |
| 16 | Entrepreneurship in the tourism industry issues in developing countries显示文摘 | Mastura J | 2011 | International Journal of Hospitality Management2011，30，4： | 1 |
| 17 | Modeling the Spatial Dynamics of Regional Land Use: The CLUE-S Model显示文摘 | PETER H. VERBURG WELMOED SOEPBOER A. VELDKAMP RAMIL LIMPIADA VICTORIA ESPALDON SHARIFAH S.A. MASTURA | 2002 | Environmental Management2002，，3： | 1 |
| 18 | Single-Step Dyeing and Formaldehyde-Free Durable Press Finishing of Cotton Fabrics显示文摘 | Raheel Mastura Guo Chen | 1998 | textile Research Journal1998，68，8： | 1 |
| 19 | Peripheral pulmonary arteries:How far in the long does multi-detector row spiral CT allow analysis?显示文摘 | Ghaye B Szapiru D Mastura L | 2001 | Radiology2001，219，： | 1 |
| 20 | Ecotourism-related products and activities,and the economic sustainability of small and medium island chalets显示文摘 | Mastura Jaafar Siti Aishah Maideen | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员