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| 1 | Gastric leaks post sleeve gastrectomy:Review of its prevention and management显示文摘Gastric sleeve gastrectomy has become a frequent bariatric procedure. Its apparent simplicity hides a number of serious,sometimes fatal,complications. This is more important in the absence of an internationally adopted algorithm for the management of the leaks complicating this operation. The debates exist even regarding the definition of a leak,with several classification systems that can be used to predict the cause of the leak,and also to determine the treatment plan. Causes of leak are classified as mechanical,technical and ischemic causes. After defining the possible causes,authors went into suggesting a number of preventive measures to decrease the leak rate,including gentle handling of tissues,staple line reinforcement,larger bougie size and routine use of methylene blue test per operatively. In our review,we noticed that the most important clinical sign or symptom in patients with gastric leaks are fever and tachycardia,which mandate the use of an abdominal computed tomography,associated with an upper gastrointrstinal series and/or gastroscopy if no leak was detected. After diagnosis,the management of leak depends mainly on the clinical condition of the patient and the onset time of leak. It varies between prompt surgical intervention in unstable patients and conservative management in stable ones in whom leaks present lately. The management options include also endoscopic interventions with closure techniques or more commonly exclusion techniques with an endoprosthesis. The aim of this review was to highlight the causes and thus the prevention modalities and find a standardized algorithm to deal with gastric leaks post sleeve gastrectomy. | Antoine Abou Rached Melkart Basile Hicham El Masri | 2014 | World Journal of Gastroenterology2014，20，38： | 14 |
| 2 | Role of vitamins in gastrointestinal diseases显示文摘A tremendous amount of data from research was published over the past decades concerning the roles of different vitamins in various gastrointestinal diseases.For instance,most vitamins showed an inverse relationship with the risk of colorectal carcinoma as well as other malignancies like gastric and esophageal cancer in observational trials,however interventional trials failed to prove a clear beneficial preventive role.On the other hand,more solid evidence was obtained from high quality studies for a role of certain vitamins in specific entities.Examples for this include the therapeutic role of vitamin E in patients with nonalcoholic steatohepatitis,the additive role of vitamins B12 and D to the standard therapy of chronic hepatitis C virus,the role of vitamin C in reducing the risk of gallstones,the positive outcome with vitamin B12 in patients with aphthous stomatitis,and the beneficial effect of vitamin D and B1 in patients with inflammatory bowel disease.Other potential uses are yet to be elaborated,like those on celiac disease,pancreatic cancer,pancreatitis,cholestasis and other potential fields.Data from several ongoing interventional trials are expected to add to the current knowledge over the coming few years.Given that vitamin supplementation is psychologically accepted by patients as a natural compound with relative safety and low cost,their use should be encouraged in the fields where positive data are available. | Omar A Masri Jean M Chalhoub Ala I Sharara | 2015 | World Journal of Gastroenterology2015，21，17： | 8 |
| 3 | Association between sarcopenic obesity and higher risk of type 2 diabetes in adults: A systematic review and meta-analysis显示文摘BACKGROUND The coexistence of sarcopenia and obesity is referred to as sarcopenic obesity(SO)and it has been hypothesized that the two components of SO may synergistically increase their negative effects. However, many uncertainties still surround this condition especially with regard to its potential negative effects on health outcomes.AIM To conduct a systematic review to determine the prevalence of sarcopenia among adults with overweight and obesity and to investigate whether SO was associated with a higher risk of type 2 diabetes(T2 D).METHODS This study was conducted in adherence with the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Literature searches, study selection, methodology development and quality appraisal were performed independently by two authors and the data were collated by means of metaanalysis and narrative synthesis.RESULTS Of the 606 articles retrieved, 11 studies that comprised a total of 60118 adults with overweight and obesity of both genders met the inclusion criteria and were reviewed, revealing two main findings. First, the overall prevalence of sarcopenia is 43% in females and 42% in males who are with overweight and obesity.Secondly, the presence of SO increases the risk of T2D by 38% with respect to those without SO(OR = 1.38, 95%CI: 1.27-1.50).CONCLUSION A high prevalence of sarcopenia has been found among adults with overweight and obesity regardless of their gender and this condition seems to be associatedwith a higher risk of T2D. Clinician should be aware of this scenario in their clinical practice for the better management of both obesity and T2D. | Dima Khadra Leila Itani Hana Tannir Dima Kreidieh Dana El Masri Marwan El Ghoch | 2019 | World Journal of Diabetes2019，10，5： | 6 |
| 4 | 基于神经网络模型的结构参数提取新方法显示文摘参数识别是结构健康监测、性能评估的关键问题之一。作为一种代表性的动力系统时域参数化模型方法,自回归滑动平均(Auto-regressive and moving average,ARMA)模型在机械和土木工程结构的参数识别中得到了广泛应用;另一方面,尽管一般而言神经网络模型的权重和阈值并不需要具备明确的物理意义,但由于神经网络具有描述复杂函数关系的能力,作为一种非参数化模型方法在结构动力系统的建模和控制领域发挥重要作用。该文首先通过结构运动平衡方程的离散时间解,证明了非参数化神经网络模型与ARMA模型在描述线性结构动力系统的响应时间序列上的等效性,在此基础上,提出了一种从结构的非参数化神经网络模型中抽取结构物理参数的新方法。通过一个多自由度系统的数值模拟结果和一个四层钢框架模型的动力试验实测数据验证了所提出的结构参数抽取方法的有效性。 | 许斌 龚安苏 贺佳 MASRI Sami F | 2011 | 工程力学2011，28，4： | 4 |
| 5 | Agmatine induces gastric protection against ischemic injury by reducing vascular permeability in rats显示文摘AIM:To investigate the effect of administration of agmatine(AGM) on gastric protection against ischemia reperfusion(I/R) injury.METHODS:Three groups of rats(6/group);sham,gastric I/R injury,and gastric I/R + AGM(100 mg/kg,i.p.given 15 min prior to gastric ischemia) were recruited.Gastric injury was conducted by ligating celiac artery for 30 min and reperfusion for another 30 min.Gastric tissues were histologically studied and immunostained with angiopoietin 1(Ang-1) and Ang-2.Vascular endothelial growth factor(VEGF) and monocyte chemoattractant protein-1(MCP-1) were measured in gastric tissue homogenate.To assess whether AKt/phosphatidyl inositol-3-kinase(PI3K) mediated the effect of AGM,an additional group was pretreated with Wortmannin(WM)(inhibitor of Akt/PI3K,15 μg/kg,i.p.),prior to ischemic injury and AGM treatment,and examined histologically and immunostained.Another set of experiments was run to study vascular permeability of the stomach using Evan's blue dye.RESULTS:AGM markedly reduced Evan's blue dye extravasation(3.58 ± 0.975 μg/stomach vs 1.175 ± 0.374 μg/stomach,P < 0.05),VEGF(36.87 ± 2.71 pg/100 mg protein vs 48.4 ± 6.53 pg/100 mg protein,P < 0.05) and MCP-1 tissue level(29.5 ± 7 pg/100 mg protein vs 41.17 ± 10.4 pg/100 mg protein,P < 0.01).It preserved gastric histology and reduced congestion.Ang-1 and Ang-2 immunostaining were reduced in stomach sections of AGM-treated animals.The administration of WM abolished the protective effects of AGM and extensive hemorrhage and ulcerations were seen.CONCLUSION:AGM protects the stomach against I/R injury by reducing vascular permeability and inflammation.This protection is possibly mediated by Akt/PI3K. | Abeer A Al Masri Eman El Eter | 2012 | World Journal of Gastroenterology2012，18，18： | 4 |
| 6 | Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation显示文摘AIM:To compare the efficacy and palatability of 4L polyethylene glycol electrolyte(PEG)plus sugar-free menthol candy(PEG+M)vs reduced-volume 2 L ascorbic acid-supplemented PEG(Asc PEG).METHODS:In a randomized controlled trial setting,ambulatory patients scheduled for elective colonoscopy were prospectively enrolled.Patients were randomized to receive either PEG+M or Asc PEG,both splitdosed with minimal dietary restriction.Palatability was assessed on a linear scale of 1 to 5(1=disgusting;5=tasty).Quality of preparation was scored by assignment-blinded endoscopists using the modified Aronchick and Ottawa scales.The main outcomes were the palatability and efficacy of the preparation.Secondary outcomes included patient willingness to retake the same preparation again in the future and completion of the prescribed preparation.RESULTS:Overall,200 patients were enrolled(100patients per arm).PEG+M was more palatable than Asc PEG(76%vs 62%,P=0.03).Completing the preparation was not different between study groups(91%PEG+M vs 86%Asc PEG,P=0.38)but more patients were willing to retake PEG+M(54%vs 40%respectively,P=0.047).There was no significant difference between PEG+M vs Asc PEG in adequate cleansing on both the modified Aronchick(82%vs77%,P=0.31)and the Ottawa scale(85%vs 74%,P=0.054).However,PEG+M was superior in the left colon on the Ottawa subsegmental score(score0-2:94%for PEG+M vs 81%for Asc PEG,P=0.005)and received significantly more excellent ratings than Asc PEG on the modified Aronchick scale(61%vs 43%,P=0.009).Both preparations performed less well in afternoon vs morning examinations(inadequate:29%vs 15.2%,P=0.02).CONCLUSION:4 L PEG plus menthol has better palatability and acceptability than 2 L ascorbic acidPEG and is associated with a higher rate of excellentpreparations;Clinicaltrial.gov identifier:NCT01788709. | Ala I Sharara Ali H Harb Fayez S Sarkis Jean M Chalhoub Rami Badreddine Fadi H Mourad Mahmoud Othman Omar Masri | 2015 | World Journal of Gastroenterology2015，21，6： | 2 |
| 7 | Flow and mixing fields of turbulent bluff-body jets and flames显示文摘 | Dally B B Fletcher D F Masri A R | 1998 | Combust Theory Modeling1998，，2： | 2 |
| 8 | Experimental studies of the effects of buffered particle dampers attached to a multi-degree-of-freedom system under dynamic loads显示文摘 | Zheng Lu Xilin Lu Wensheng Lu Sami F. Masri | 2011 | Journal of Sound and Vibration2011，，9： | 2 |
| 9 | 显示文摘 | Duncan C P Masri B | 1993 | J Bone Joint Surg (Br)1993，75，： | 1 |
| 10 | MUC1 affects c-Src signaling in PyV MT-induced mammary tumorigenesis显示文摘 | Al Masri A Gendler SJ | 2005 | Oncogene2005，24，38： | 1 |
| 11 | A biomechanical study comparing cortical onlay allograft struts and plates in the treatment of periprosthetic femoral frac- tures 显示文摘 | Wilson D Frei H Masri BA | 2005 | Clin Biomech2005，20，1： | 1 |
| 12 | Expression of the murine msr/apj receptor and its ligand apelin is up regulated during formation of theretinal vessels显示文摘 | Geniez S Masri B Malecaze F | 2002 | Mech Dev2002，110，4： | 1 |
| 13 | Electrocardiographic signs of remote myocardial infaretion显示文摘 | Michael MA El Masry H Khan BR | 2007 | Prog Cardiovase Dis2007，50，： | 1 |
| 14 | A scalable wavelet- based video distortion metric and applications显示文摘 | Masry M Hemami S S Sermadevi Y | 2006 | IEEE Transactions on Circuits and Systems for Video Technology2006，16，2： | 1 |
| 15 | Genome-wide analysis of aromatase inhibitor-resistant,tamoxifen-resistant,and long-term estrogen-deprived cells reveals a role for estrogen receptor显示文摘 | MASRI S PHUNG S WANG X | | 0，，12： | 1 |
| 16 | Relationship of high sensitivity C- reactive protein with presence and severity of coronary artery disease 显示文摘 | Habib S S Masri A | 2013 | Pak J Med Sci2013，29，6： | 1 |
| 17 | Nondestructive determination of water-holding capacity in fresh beef by using NIR hyperspectral imaging显示文摘 | El MASRY G SUN D W ALLEN P | 2011 | Food Research International2011，44，： | 1 |
| 18 | Structural proximal femoral allografts for failed total hip replacements : a minimum re- view of five years 显示文摘 | Haddad FS Garbuz DS Masri BA | 2000 | J Bone Joint Surg Br2000，82，6： | 1 |
| 19 | Apelin,a newly identified adipokine up-regulated by insulin and obesity显示文摘 | Boucher J Masri B Daviaud D | 2005 | Endocr inology2005，146，4： | 1 |
| 20 | Soil organic matter and related physical properties in a Mediterranean wheat-based rotation trial显示文摘 | Masri Z Ryan J | 2006 | Soil and Tillage Research2006，87，： | 1 |
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