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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 3 | Emergence of carbapenem resistance in Acinetobacter baumannii in the Czech Republic is associated with the spread of multidrug resistant strains of European clone Ⅱ 显示文摘 | Alexandr N Lenka K Martina M | 2008 | d Antimicrob Chemother2008，62，3： | 1 |
| 4 | Bacillus and Streptomyces Were Selected as Broad-Spectrum Antagonists Against Soilborne Pathogens from Arid Areas in Egypt 显示文摘 | MARTINA K ELAHAHAT M R MOHAMED A | 2013 | Federation of European Microbiological Societies Microbiol Letters2013，342，： | 1 |
| 5 | Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea 显示文摘 | Mueller C Scholer A Laule-Kilian K Martina B Schindler C Buser P Pfisterer M Perruchoud AP | 2004 | N Engl J Med2004，350，： | 1 |
| 6 | Biotransformation of PCBs by plants and bacteria - consequences of plant-microbe interactions 显示文摘 | Martina M Vrehotova B Francova K | 2007 | European Journal of Soil Biology2007，43，4： | 1 |
| 7 | The clinical conscientiousness in- dex:a valid tool for exploring professionalism in the clinical under- graduate setting显示文摘 | Martina K Siun O John M | 2012 | Acad Meal2012，87，9： | 1 |
| 8 | Anthocyanin content and antioxidam activity of various red fruit juices显示文摘 | LIDIJA J MARUAN S MARTINA M K | 2007 | Dtsoh Lebensm- Rundsch2007，103，2： | 1 |
| 9 | Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonism显示文摘 | Jos H M Lange Hein K A C Coolen Martina A W van der Neut | 2010 | J Med Chem2010，53，3： | 1 |
| 10 | Anthocyanin content and antioxidant activity of various red fruit juices 显示文摘 | Lidija J Marijan S Martina M K | 2007 | Dtsch Lebensm Rundsch2007，103，2： | 1 |
| 11 | New poly ether ether ketones containing phosphorus for membrane preparation显示文摘 | TROTTA F CERESA M S MARTINA K | 2010 | Asia-Pac J Chem Eng2010，5，1： | 1 |
| 12 | Effect of amine and thiol addition on the surface chemistry and agglomeration of fine Cu powders显示文摘 | PETER J U MARTINA E R SUZANNE M K ALAN E N | | 0，，： | 1 |
| 13 | Synthesis and characterization of polymeric nanospheres loaded with the anticancer drug paclitaxel and magnetic particles显示文摘 | Vlasta Z Martina K Marta M | 2009 | J Magnetism Magnetic Materials2009，321，10： | 1 |
| 14 | Cystatin C and cardiovascular mortality in patients with coronary artoy disease and normalormildly reduced kidney function results from the Atherogene study显示文摘 | Till K Claudia Martina M Edith L | 2009 | Eur Heart2009，30，5： | 1 |
| 15 | Epithelial endoplasmicreticulum stress and apoptosis in sporadic idiopcathic pulmonaryfibrosis显示文摘 | Martina K Clemens R Poornima M | 2008 | Am J Respor Crit Care Med2008，178，： | 1 |
| 16 | Annealing study of a bistable defect in proton- implanted n - type 4H-SiC 显示文摘 | NIELSENA H K MARTINA D M LEVEQUE P | 2003 | Physica B : Condensed Matter2003，340，： | 1 |
| 17 | Isolation and identification of intermediates from biodegradation of low chlorinated biphenyls (Delor-103)显示文摘 | Triska J Gabriela K Martina M Novakova H Jaakko P Miria L Nadezda V | 2004 | Chemosphere2004，54，： | 1 |
| 18 | Effects of erythropoietin on erythrocyte deformability in non-transfused preterm infants显示文摘 | MARTINA K ANNE-ULRIKE H JOHANNES M P | 2007 | Acta Paediatrica2007，，96： | 1 |
| 19 | The influence of international networks on internationalization speed and performance:A study of Czech SMEs显示文摘 | Martina M John F and Datta D K | 2010 | Journal of World Business2010，45，3： | 1 |
| 20 | Douglas-fi r(Pseudotsuga menziesii(Mirb.)Franco)in Europe:an overview of management practices显示文摘Douglas-fir(Pseudotsuga menziesii(Mirb.)Franco),one of the most commercially important tree species in western North America and one of the most valuable timber trees worldwide,was introduced to Europe in 1827.It became a major species for aff orestation in Western Europe after WWII,currently grows in 35 countries on over 0.83 million ha and is one of the most widespread nonnative tree species across the continent.A lower sensitivity to drought makes Douglas-fi r a potential alternative to the more drought-sensitive Norway spruce so its importance in Europe is expected to increase in the future.It is one of the fastest growing conifer species cultivated in Europe,with the largest reported dimensions of 2.3 m in diameter and 67.5 m in height.Pure stands have high productivity(up to 20 m 3 ha−1 a−1)and production(over 1000 m 3 ha−1).The species is generally regenerated by planting(initial stocking density from less than 1000 seedlings ha−1 to more than 4000 ha−1),using seedlings of European provenance derived from seed orchards or certifi ed seed stands.As the range of end-uses of its wood is very wide,the rotation period of Douglas-fi r is highly variable and ranges between 40 and 120 years.When the production of large-sized,knotfree timber is targeted,thinnings are always coupled with pruning up to 6 m.There is an increasing interest in growing Douglas-fi r in mixtures and managing stands through close-to-nature silviculture,but the species’intermediate shade tolerance means that it is best managed through group selection or shelterwood systems. | Valeriu-Norocel Nicolescu William LMason Jean-Charles Bastien Torsten Vor Krasimira Petkova Vilém Podrázský Martina Đodan Sanja Perić Nicola La Porta Robert Brus Siniša Andrašev Martin Slávik Juraj Modranský Michal Pástor Károly Rédei Branislav Cvjetkovic Ahmet Sivacioğlu Vasyl Lavnyy Cornelia Buzatu-Goanță Gheorghe Mihăilescu | 2023 | Journal of Forestry Research2023，34，4： | 0 |
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