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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Spontaneous fungal peritonitis: Micro-organisms, management and mortality in liver cirrhosis-A systematic review显示文摘BACKGROUND Spontaneous peritonitis is an infection of ascitic fluid without a known intraabdominal source of infection. spontaneous fungal peritonitis (SFP) is a potentially fatal complication of decompensated cirrhosis, defined as fungal infection of ascitic fluid in the presence of ascitic neutrophil count of greater than 250 cells/mL. AIM To determine the prevalence of fungal pathogens, management and outcomes (mortality) of SFP in critically ill cirrhotic patients. METHODS Studies were identified using PubMed, EMBASE, Cochrane Central Register of Controlled Trials and Scopus databases until February 2019. Inclusion criteria included intervention trials and observation studies describing the association between SFP and cirrhosis. The primary outcome was in-hospital, 1-mo, and 6- mo mortality rates of SFP in cirrhotic patients. Secondary outcomes were fungal microorganisms identified and in hospital management by anti-fungal medications. The National Heart, Lung and Blood Institute quality assessment tools were used to assess internal validity and risk of bias for each included study. RESULTS Six observational studies were included in this systematic review. The overall quality of included studies was good. A meta-analysis of results could not be performed because of differences in reporting of outcomes and heterogeneity of the included studies. There were 82 patients with SFP described across all the included studies. Candida species, predominantly Candida albicans was the fungal pathogen in majority of the cases (48%-81.8%) followed by Candida krusei (15%- 25%) and Candida glabrata (6.66%-20%). Cryptococcus neoformans (53.3%) was the other major fungal pathogen. Antifungal therapy in SFP patients was utilized in 33.3% to 81.8% cases. The prevalence of in hospital mortality ranged from 33.3% to 100%, whereas 1-mo mortality ranged between 50% to 73.3%. CONCLUSION This systematic review suggests that SFP in end stage liver disease patient is associated with high mortality both in the hospital and at 1-mo, and that antifungal therapy is currently underutilized. | Tooba Tariq Furqan B Irfan Mehdi Farishta Brian Dykstra Eric Martin Sieloff Archita P Desai | 2019 | World Journal of Hepatology2019，11，7： | 7 |
| 3 | Biological therapy in inflammatory bowel diseases:Access in Central and Eastern Europe显示文摘Biological drugs opened up new horizons in the management of inflammatory bowel diseases(IBD).This study focuses on access to biological therapy in IBD patients across 9 selected Central and Eastern European(CEE)countries,namely Bulgaria,the Czech Republic,Estonia,Hungary,Latvia,Lithuania,Poland,Romania and Slovakia.Literature data on the epidemiology and disease burden of IBD in CEE countries was systematically reviewed.Moreover,we provide an estimation on prevalence of IBD as well as biological treatment rates.In all countries with the exception of Romania,lower biological treatment rates were observed in ulcerative colitis(UC)compared to Crohn’s disease despite the higher prevalence of UC.Great heterogeneity(up to 96-fold)was found in access to biologicals across the CEE countries.Poland,Bulgaria,Romania and the Baltic States are lagging behind Hungary,Slovakia and the Czech Republic in their access to biologicals.Variations of reimbursement policy may be one of the factors explaining the differences to a certain extent in Bulgaria,Latvia,Lithuania,and Poland,but association with other possible determinants(differences in prevalence and incidence,price of biologicals,total expenditure on health,geographical access,and cost-effectiveness results)was not proven.We assume,nevertheless,that healthdeterioration linked to IBD might be valued differently against other systemic inflammatory conditions in distinct countries and which may contribute to the immense diversity in the utilization of biological drugs for IBD.In conclusion,access to biologicals varies widely among CEE countries and this difference cannot be explained by epidemiological factors,drug prices or total health expenditure.Changes in reimbursement policy could contribute to better access to biologicals in some countries. | Fanni Rencz Márta Péntek Martin Bortlik Edyta Zagorowicz Tibor Hlavaty Andrzej Sliwczyński Mihai M Diculescu Limas Kupcinskas Krisztina B Gecse László Gulácsi Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，6： | 4 |
| 4 | 烤烟,白肋烟和香料烟(Nicotiana tabacum)烟叶中镉浓度的调查显示文摘 | LLUGON-MOULIN N MARTIN F KRAUSS M R RAMEY P B ROSSIL 吴晓芸(译) 康婧(校) | 2006 | 中国烟草学报2006，12，6： | 3 |
| 5 | Formation of an ant cemetery: Swarm intelligence of statistical accident显示文摘 | Martin M Chopard B Albuquerque P | 2002 | Future Generation Computer Systems2002，18，： | 2 |
| 6 | Comparison of fluticasone propionate aqueous nasal spray and oral montelukast for the treatment of seasonal allergic rhinitis symptoms显示文摘 | MARTIN B G ANDREWS C P VAN BAVEL J H | 2006 | Ann Allergy Asthma Immunol2006，96，： | 1 |
| 7 | Finite element studies of the deformation of the pelvic floor显示文摘 | MARTINS J A PATO M P PIRES E B | 2007 | Ann N Y Acad Sci2007，1101，： | 1 |
| 8 | Pore water pressure changes during soils liquefaction显示文摘 | Seed H B Martin P P and Lysmer J | 1976 | Journal of Geotechnical Engineering Division ASCE1976，102，4： | 1 |
| 9 | Unreduced posterior luxations and fractures-luxations of the shoulder: a propos of 30 cases 显示文摘 | Walch G Boileau P Martin B etal | 1990 | Rev Chir Orthop Reparatfice Appar Mot1990，76，8： | 1 |
| 10 | Layer-bylayer assembly of ultrathin composite films from micron-sized graphite oxide sheets and polycations显示文摘 | Kovtyukhova N I Ollivier P J Martin B R | | 0，，03： | 1 |
| 11 | Revisiting the fundamental of single point incremental forming by means of mem- brane analysis显示文摘 | Silva M B Skjoedt M Martins P A F | 2008 | International Journal of Machine Toll & Manufacture2008，48，1： | 1 |
| 12 | Inflammatory cytokines in patient with persistence of ARDS显示文摘 | Goodman R B Martin D P Walz A | 1996 | Am J Respir Crit Care Med1996，154，： | 1 |
| 13 | Responses of Stylosanthes humilis (Fabaceae) populations to saline stress显示文摘 | Lovato M B De Lemos Filho J P Martins P S | 1999 | Environmental and Experimental Botany1999，41，： | 1 |
| 14 | Coro- nary perfusion pressure and the return of pontancous cireula- tion in human cardiopulmonary resuscitation 显示文摘 | PARADIS N A MARTIN G B RIVERS E P | 1990 | JAMA1990，263，： | 1 |
| 15 | Formation of an ant cemetery: Swarm intelligence or statistical accident显示文摘 | Martin M Chopard B Albuquerque P | 2002 | Future Generation Computer Systems2002，18，7： | 1 |
| 16 | An NB-LRR protein required for HR signalling mediated by both extra-and intracellular resistance proteins显示文摘 | Gabrils S H E J Vossen J H Ekengren S K Ooijen G Abd-El-Haliem A M Berg G Rainey D Y Martin G B Takken F L W Wit P J G M | 2007 | The Plant Journal2007，50，1： | 1 |
| 17 | Layer-by-Layer Assembly of Ultrathin Composite Films from Micron-Sized Graphite Oxide Sheets and Polycations显示文摘 | Kovtyukbova N I Ollivier P J Martin B R | | 0，，03： | 1 |
| 18 | Layer-by-layer assembly of ultrathin composite films from micron-sized graphite oxide sheets and polycations显示文摘 | Kovtyukhova N I Ollivier P J Martin B R | 1999 | Chem Mater1999，11，3： | 1 |
| 19 | Evidence for chilling induced oxidative stress in maize seedlings and a regulatory role for hydrogen peroxide显示文摘 | Prasad T K Anderson M P Martin B A | 1994 | Plant Cell1994，6，： | 1 |
| 20 | More clues about sensory impact of sotolon in some flor sherry wines显示文摘 | Martin B Etevant P X Quere J | 1992 | J Agric Food Chem1992，40，： | 1 |
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