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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts显示文摘The accumulation and aggregation of alpha-synuclein(α-syn)in several tissue including the brain is a major pathological hallmark in Parkinson’s disease(PD).In this study,we show that α-syn can be taken up by primary human cortical neurons,astrocytes and skin-derived fibroblasts in vitro.Our findings that brain and peripheral cells exposed to α-syn can lead to impaired mitochondrial function,leading to cellular degeneration and cell death,provides additional evidence for the involvement of mitochondrial dysfunction as a mechanism of toxicity of α-syn in human cells. | Nady Braidy Wei-Ping Gai Ying Hua Xu Perminder Sachdev Gilles J Guillemin Xing-Mai Jiang J William O Ballard Martin P Horan Zhi Ming Fang Beng H Chong Daniel Kam Yin Chan | 2013 | Translational Neurodegeneration2013，2，1： | 4 |
| 3 | Parvovirus B19 induced hepatic failure in an adult requiring liver transplantation显示文摘Parvovirus B19 induced acute hepatitis and hepatic failure have been previously reported, mainly in children. Very few cases of parvovirus induced hepatic failure have been reported in adults and fewer still have required liver transplantation. We report the case of a 55-year-old immunocompetent woman who developed fulminant hepatic failure after acute infection with Parvovirus B19 who subsequently underwent orthotopic liver transplantation. This is believed to be the first reported case in the literature in which an adult patient with fulminant hepatic failure associated with acute parvovirus B19 infection and without hematologic abnormalities has been identified prior to undergoing liver transplantation. This case suggests that Parvovirus B19 induced liver disease can affect adults, can occur in the absence of hematologic abnormalities and can be severe enough to require liver transplantation. | Darin S Krygier Urs P Steinbrecher Martin Petric Siegfried R Erb Stephen W Chung Charles H Scudamore Andrzej K Buczkowski Eric M Yoshida | 2009 | World Journal of Gastroenterology2009，15，32： | 3 |
| 4 | Comparison of fluticasone propionate aqueous nasal spray and oral montelukast for the treatment of seasonal allergic rhinitis symptoms显示文摘 | MARTIN B G ANDREWS C P VAN BAVEL J H | 2006 | Ann Allergy Asthma Immunol2006，96，： | 1 |
| 5 | Functional characteriza- tion of the EMCV IRES in plants显示文摘 | Urwin P Yi L Martin H | 2000 | The Plant Jour- pal2000，24，： | 1 |
| 6 | Pore water pressure changes during soils liquefaction显示文摘 | Seed H B Martin P P and Lysmer J | 1976 | Journal of Geotechnical Engineering Division ASCE1976，102，4： | 1 |
| 7 | Wedge-and-strip anodes for centroid-finding position-sensitive photon and particle detectors显示文摘 | MARTIN C JELINSKY P ANGER H O | 1987 | Rev Sci Instrum1987，52，7： | 1 |
| 8 | Communication between eph- rinB2 and EphB4 within the osteoblast lineage 显示文摘 | Martin T J Allan E H Ho P W | 2010 | Adv Exp Med Biol2010，658，： | 1 |
| 9 | Particulate air pollution and daily mortality on Utah's wasatch front 显示文摘 | Arden P C Randy W H Martin G V | 1999 | Environmental Health Perspectives1999，107，7： | 1 |
| 10 | The Influence of Lactose Carrier on the Content Homogeneity and Dispersibility of Beclomethasone Dipropionate from Dry Powder Aerosols 显示文摘 | ZENG X M PANDHAL K H MARTIN G P | 2000 | International Journal of Pharmaceutics2000，197，： | 1 |
| 11 | Sulfuric activation of a brazilian manganese ore for heavy metals removal显示文摘 | RESENDE P C BARRADO F S MARTINS A H | 1999 | Hydrometallurgy1999，51，3： | 1 |
| 12 | The key roles of elongases and desaturases in mammalian fatty acid metabolism:insights from transgenic mice显示文摘 | GUILLOU H ZADRAVEC D MARTIN P G | | 0，，： | 1 |
| 13 | Poly- ethylenimine-graft-poly ( ethylene glycol) copolymers: influ- ence of copolymer block structure on DNA complexation and biological activities as gene delivery system 显示文摘 | PETERSEN H FECHNER P M MARTIN A L | 2002 | Bioconjugate Chem2002，13，4： | 1 |
| 14 | An NB-LRR protein required for HR signalling mediated by both extra-and intracellular resistance proteins显示文摘 | Gabrils S H E J Vossen J H Ekengren S K Ooijen G Abd-El-Haliem A M Berg G Rainey D Y Martin G B Takken F L W Wit P J G M | 2007 | The Plant Journal2007，50，1： | 1 |
| 15 | Life cycle assessment of carbon dioxide capture and storage from lignite power plants显示文摘 | Martin P Johannes H | 2009 | International Journal of Greenhouse Gas Control2009，3，1： | 1 |
| 16 | Adefovir dipivoxil (ADV) alone and in combination with lamivudine (LAM)suppress YMDD mutant hepatitis B virus replication:48 week preliminary analysis显示文摘 | Marion P H W Hann P Martin | 2002 | Hepatology2002，36，： | 1 |
| 17 | Sustained release of vascular endothelial growth factor from mineralized poly (lactide-co-glycolide) scaffolds for tissue engineering显示文摘 | WILLIAM L M MARTIN C P DAVID H | 2000 | Biomaterials2000，21，： | 1 |
| 18 | Characterization of a common precursor population for dendritic ceils 显示文摘 | Hoyo CM Martin P Vargas H | 2002 | Nature2002，415，6875： | 1 |
| 19 | Spinal neurenteric cyst presenting in infancy with chronic fever and acute myelopathy显示文摘 | Kadhim H Guzman Proano P Saint Martin C | 2000 | Neurology2000，54，： | 1 |
| 20 | Pore-water pressure changes during soil liquefaction 显示文摘 | Seed H B Martin P P Lysmer J | 1976 | American Society of Civil Engineers Journal of the Geotechnical Engineering Division1976，102，4： | 1 |
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