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    题名 作者 年代 出处 被引量
1Hepatocellular carcinoma in central Sydney :a 10yearreview of patients seen in a medical oncology department显示文摘AIM To report a single Australian oncology unit′s experience with the management of patients with hepatocellular carcinoma (HCC), in the context of a literature review of the current management issues. METHODS Retrospective case record review of 76 patients with diagnosis of HCC referred to the unit between 1984 and 1995. RESULTS Sixty three patients had adequate records for analysis. Thirty six (56%) were migrants with half from Southeast Asia. Twenty four patients had a documented viral aetiology. Nine (14%) of 51 patients with pathological confirmation of HCC had normal alpha fetoprotein levels. Median survival of the 20 patients managed palliatively was 5 weeks compared to 16 weeks for the cohort overall. Surgery in 16 patients rendered all initially disease free with a median survival of 88 weeks. Chemoembolisation induced tumor responses in 5 of the 11 patients so treated. Systemic chemotherapy and tamoxifen treatment caused tumor response in two of 12 and one of 25 respectively. CONCLUSION Prolonged survival of patients with HCC depends on early detection of small tumors suitable for surgical resection. Other active treatments are palliative in intent and have limited success. In addition to tumor response and survival duration, the toxicities of therapies and the overall quality of life of patients need to be considered as important outcomes. Viral hepatitis prevention and screening of individuals at risk are strategies that are important for HCC management in communities where the disease is endemic.Desmond Yip 1, Michael Findlay 2, Michael Boyer 1 and Martin H. Tattersall 3 1999World Journal of Gastroenterology1999,5,6:17
2Experimental plant and the technological transfer centre: urban wastewater treatment experimental platforms for the small rural communities in the mediterranean area显示文摘FAHD K MARTIN 1 SALAS J 2007Desalination2007,215,:1
3Mutinous cystic neoplasms of the pancreas: imaging features and diagnostic difficuhies显示文摘Scott J Martin 1 Redhead D 2000Clin Radiol2000,55,3:1
4Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering 显示文摘Vunjak-Novakovic G Obradovic B Martin 1 1998Biotechnology Progress1998,14,2:1
5Rapid in?crease in hospitalization and mortality rates for severe sepsis in the United States: a tread analysis from 1993 to 2003显示文摘Dombrovskiy VY Martin AA Sunderram 1 2007Crit Care Med2007,35,5:1
6Real - time PCR for detection and quantification of red deer ( Cervus elaphus), fallow deer ( Dama danm), and roe deer (Capreolus capreolus) in meat mixtures 显示文摘Fajardo V Gonzalez 1 Martin I 2008Meat Science2008,79,2:1
7Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes显示文摘Leal EC 1 Martins J Voabil P 2010Diabetes2010,59,1:1
8Analysis of volatile nitrosamines from a model system using SPME-DED at diferent temperatures and times of extraction 显示文摘Ventanas S Martin D Estevenz M eta 1 2006Food Chem2006,99,4:1
9Distribution of UidA Gene Sequences in Escheridlia coli Isolates in Water Sources and Comparison with the Expression of β-glucuronidase Activity in 4- methylumbelliferyl-β-D-glucuronide Media 显示文摘MARTINS M T IVERA 1 G CLARK D L 1993Applied and Envi- ronment Microbiology1993,59,:1
10Miscarriage karyotype and its relationship with maternal body mass index, age, and mode of conception 显示文摘Kroon 1 Harrison K Martin N 2011Fertil Steril2011,95,5:1
11Hygromycin resistance as an efficient selectable marker for wheat stable transformation显示文摘Juan Pablo A Ortia Martin 1 Reggiardo Ricardo A Ravizzini 0,,:1
12Is project management: size, practices and the project management office 显示文摘Nancy 1 Martin J Michael Pearson Kimberly Furumo 2007Journal of Computer InformationSystems2007,47,4:1
13Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally incasivbe breast cancer显示文摘de Silva Rudland S Martin 1 Roshanlall C 2006Clin Cancer Res2006,12,4:1
14Analysis of the allele-specific expression of the mismatch repair geneMLH1 using a simple DHPLC-based method显示文摘Tournier I Raux G Di Fiore F Mar6chal 1 Leclerc C Martin C Wang Q Buisine MP Stoppa- Lyonnet D Olschwang S Frabourg T Tosi M 2004Hum Mutat2004,23,4:1
15An unexpected selectivity of a propranolol-derived molecular imprint for tamoxifen 显示文摘Martin P D Wilson T D Wilson 1 D 2001Analyst2001,31,:1
16Explaining organi- zational responsiveness to work - family issues : the role of human resource executives as issue interpreters 显示文摘Milliken F J Martins L 1 Morgan H 1998The Academy of Management Journal1998,41,5:1
17The influence of plantsgrown under elevated C02 and N fertilization on soil nitrogen dynam-ics显示文摘Martin - Olmedol P Rees R M Grace 1 J 2002Global Change Biology2002,8,7:1
18A myocardial lineage derives from Thx18 epicardial cells显示文摘Cai C L Martin 1 C Sun Y 2008Nature2008,454,7200:1
19The carri6n de los c6spedes experimental plant and the technological transfer centre : Urban wastewater treatment experimental platforms for the small rural communities in the Mediterranean area 显示文摘FAHD K MARTIN 1 SALASJ J 2007Desalination2007,215,13:1
20Multiplex PCR for the detection of tetracycline resistant genes 显示文摘NG L K MARTIN 1 ALFA M 2001Molecular and Cellular Probes2001,15,:1
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