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| 1 | Prevention of overuse: A view on upper gastrointestinal endoscopy显示文摘Many upper gastrointestinal(GI) endoscopies worldwide are performed for inappropriate indications. This overuse of healthcare negatively affects healthcare quality and puts pressure on endoscopy services. Dyspepsia is one of the most common inappropriate indications for upper GI endoscopy as diagnostic yield is low. Reasons for untimely referral are: unfamiliarity with dyspepsia guidelines,uncertainty about etiology of symptoms, and therapy failure. Unfiltered openaccess referrals feed upper GI endoscopy overuse. This review highlights strategies applied to diminish use of upper GI endoscopies for dyspepsia. First,we describe the impact of active guideline implementation. We found improved guideline adherence, but resistance was encountered in the process. Secondly, we show several forms of clinical assessment. While algorithm use reduced upper GI endoscopy volume, effects of referral assessment of individual patients were minor. A third strategy proposed Helicobacter pylori test and treat for all dyspeptic patients. Many upper GI endoscopies can be avoided using this strategy, but outcomes may be prevalence dependent. Lastly, empirical treatment with Proton pump inhibitors achieved symptom relief for dyspepsia and avoided upper GI endoscopies in about two thirds of patients. Changing referral behavior is complex as contributing factors are manifold. A collaboration of multiple strategies is most likely to succeed. | Judith J de Jong Marten A Lantinga Joost PH Drenth | 2019 | World Journal of Gastroenterology2019，25，2： | 3 |
| 2 | Paternal leakage of mitochondrial DNA in the great tit ( Parus major) 显示文摘 | KVIST L MARTENS J NAZARENKO A A | 2003 | Mol Biol Evol2003，20，2： | 1 |
| 3 | Benthic fluxes and porewater concentration profiles of dissolved organic carbon in sediments from the North Carolina continental slope显示文摘 | Alperin M J Martens C S Albert D B | 1999 | Geochimica et Cosmochimica Acta1999，63，： | 1 |
| 4 | Cytokeratin 17 andP63 are markers of the HPV target cell,t he cervical stemcell显示文摘 | Martens JE Arends J Linden P | | 0，，02： | 1 |
| 5 | Phylogeny of long-tailed tits and allies inferred from mitochondrial and nuclear markers (Aves:Passeriformes,Aegithalidae)显示文摘 | P(a)ckert M Martens J Sun Y-H | | 0，，： | 1 |
| 6 | Tuberculosis susceptibility of diabetic mice 显示文摘 | Martens GW Arikan MC Lee J | 2007 | Am J Respir Cell Mol Biol2007，37，5： | 1 |
| 7 | DNA methyl-ation asa biomarker in breast cancer显示文摘 | Martens J W Margossian A L Schmitt M | 2009 | Future Oncol2009，5，8： | 1 |
| 8 | Estimation of perceived image blur using edge features显示文摘 | Vishwakumara K Martens J B | 1996 | International Journal of Imaging Systems and Technology1996，7，： | 1 |
| 9 | The Hermite transform-theory显示文摘 | Martens J B | 1990 | IEEE Trans Acoust Speech Signal Processing1990，38，9： | 1 |
| 10 | Microbial production of vitamin Bit 显示文摘 | Martens J H Barg H Warren M J | 2002 | Applied Microbiology and Bioteehnology2002，58，3： | 1 |
| 11 | Crystallines microporous phosphates: A family of versatile catalysts and adsorbents 显示文摘 | MARTENS J M JACOBS P A | 1994 | Studies in Surface Science and Catalysis1994，85，： | 1 |
| 12 | Estimation of the void structure and pore dimensions of molecular sieve zeo- lites using the hydroconversion of n-deeane 显示文摘 | Martens J A Tielen M Jacobs P A | 1984 | Zeolites1984，4，2： | 1 |
| 13 | The effect of different post weaning altrenogest treatments of primiparous sows on follicular development,pregnancy rates,and litter sizes显示文摘 | Leeuwen van J J J Williams S I Martens M | 2011 | Journal of Animal Science2011，89，2： | 1 |
| 14 | Hemp fiber as a textile resource显示文摘 | MUSSIG J MARTENS R HARIG H | 1998 | Textile Asia1998，29，5： | 1 |
| 15 | Isomerization and hydrocracking of heptane over bimetallic bifunctional Pt- Pd/H - Beta and PtPd/USY zeolite catalysts 显示文摘 | Blomsma E Martens J A Jacobs P A | 1997 | J Catal1997，165，： | 1 |
| 16 | Classical-quantum correspondence in the presence of global chaos显示文摘 | Waterland R L Yuan J M Martens C C | 1988 | Phys Rev Lett1988，61，24： | 1 |
| 17 | Biogeochemical cycling in an organic rich coastal marine basin(Ⅱ): Nutrient sediment - waters exchange processes显示文摘 | Martens C S | 1981 | Geochemical Cosmochimica Acta1981，45，： | 1 |
| 18 | The Hermite transform-application显示文摘 | Martens J B | 1990 | IEEE Trans on Acoustics Speech and Signal Processing1990，38，9： | 1 |
| 19 | Tuberculosis susceptibility of diabetic mice显示文摘 | Martens GW Arikan MC Lee J | 2011 | Am J Respir Cell Mol Biol2011，37，5： | 1 |
| 20 | The Potential and Limitatoins of then-Decane Hydroconversion a Test Reaction for Characteriza- tion of the Void Space of Molecular Sieve Zeolites 显示文摘 | Martens J A Jacobs P A | 1986 | Zeo- lites1986，6，5： | 1 |
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