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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Incidental dose to clinical negative nodes from conformal treatment fields for nonsmall cell lung cancer 显示文摘 | Sahijdak WM Ball D | 1999 | Int J Radiat Oncol Biol Phys1999，45，3： | 1 |
| 3 | Effects of temperature during early life history on embryonic and larval development and growth in haddock显示文摘 | Martell D J Kieffer J D Trippel E A | 2005 | Journal of Fish Biology2005，66，： | 1 |
| 4 | An index for tracking sheltered forest floor moisture within the Canadian Forest Fire Weather Index System显示文摘 | Wotton B M Stocks B J Martell D L | 2005 | International Journal of Wildland Fire2005，14，2： | 1 |
| 5 | Global burden of human papillomavirus and related diseases显示文摘 | Forman D de Martel C Lacey C J | 2012 | Vaccine2012，30，5： | 1 |
| 6 | A decision support system that links short - term silvicultural operating plans with long - term forest- level strategic plans 显示文摘 | Davis R G Martell D L | 1993 | Can J For Res1993，23，6： | 1 |
| 7 | Dioxygen affinities of synthetic co- balt Schiff base complexes 显示文摘 | Chen D Martell A E | 1987 | Inorg Chem1987，26，： | 1 |
| 8 | Effects of mesangium glycation on matrix metallo-proteinase activities:possible role in diabetic nepbropatby 显示文摘 | Mclennan S V Martell S K Yue D K | 2002 | Diabetes2002，51，8： | 1 |
| 9 | Finishing of polyester fabrics with cyclodextrins and polycarboxylic acids as crosslinking agents显示文摘 | Martel B Moreellet M Ruffin D | 2002 | Incl Phenom Macro Chem2002，，44： | 1 |
| 10 | New synthetic cobalt schiff base complexes as oxygen carriers 显示文摘 | I Chen D Martell A E Sun Y | 1989 | Inorg Chem1989，28，： | 1 |
| 11 | Scanning electron microscopy of postovulatory human endometrium in spontaneous cycles and cycles stimulated by hormonetreatment显示文摘 | Martel D Frydman R Glissant M | 1987 | Endocrinol1987，11，4： | 1 |
| 12 | Definding the CP50 and for propofol alone and propofol with alfentanil显示文摘 | Howell S Can D Martel D | 1995 | Anesthesiology1995，83，9： | 1 |
| 13 | Gastric cancer : epidemiolo- gy and risk factors显示文摘 | de Martel C Forman D Plummer M | 2013 | Gastroenterol Clin North Am2013，42，2： | 1 |
| 14 | Diversity of extended - spectrum beta - lactamases and class C beta - lactamases among clo- acal Escherichia coli Isolates in Belgian broiler farms 显示文摘 | SMET A MARTEL A PERSOONS D | 2008 | Antimicrob Agents Chemother2008，52，4： | 1 |
| 15 | Acute tracheoesophageal burst injury after blunt chest trauma: case report and review of the literature 显示文摘 | MARTEL G AL-SABTI H MULDER D S | 2007 | J Trauma2007，62，1： | 1 |
| 16 | Purported nanobacteria in human blood as calcium carbonate nanoparticles 显示文摘 | Martel J Young J D -E | 2008 | Proceedings of the National A- cademy of Sciences2008，105，： | 1 |
| 17 | High glucose concentration inhibits the expression of membrane type metalloproteinase by mesangial cells:possible role in mesangium accumulation 显示文摘 | McLennan S V Martell S Y Yue D K | 2000 | Diabetologia2000，43，5： | 1 |
| 18 | Immunomodulatory effects of probiotics in the intestinal tract显示文摘 | Deleenserie V Martel D Lamoureux M | 2008 | Current Issues in Molecular Biology2008，10，12： | 1 |
| 19 | Fetuin-A/Albumin-Mineral Com-plexes Resembling Serum Calcium Granules and PutativeNanobacteria:Demonstration of a Dual Inhibition-Seeding Concept显示文摘 | Wu CY Martel J Young D | 2009 | PLoS One2009，4，11： | 1 |
| 20 | Age dependent association of endometrial polyps with increased risk of cancer involvenrmt显示文摘 | Hilecto D Fadare O Martel M | 2005 | World J Surg Oncol2005，3，1： | 1 |
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