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| 1 | 症状严重程度比认知缺损更与精神分裂症住院患者的社会功能状况密切相关(英文)显示文摘背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低。目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系。方法选取上海市精神卫生中心的51例住院男性精神分裂症患者,其中40例患者最终完成了个体和社会功能量表(Personal and Social Performance Scale,PSP)中文版、临床疗效总评量表-病情严重程度量表(Clinical Global Impression-Severity,CGI-S)、阳性和阴性症状量表(Positive and Negative Symptom Scale,PANSS)、字母-数字排序以及香港文字记忆学习测试等项目的评定。结果患者PANSS量表的3个临床分量表的分值和社会功能总体评估(PSP总分和CGI-S分值)之间存在明显负相关。患者的神经认知测定结果与症状或社会功能状况均无关。结论对于急性期住院精神分裂症患者而言,临床症状的严重度—而非神经认知缺损程度,与其社会功能水平密切相关。 | 左赛 Linda K.BYRNE 彭代辉 David MELLOR Marita McCABE 张洁 黄佳 徐一峰 | 2012 | 上海精神医学2012,24,2: | 8 |
| 2 | Dysfunction of cognition patterns measured by MATRICS Consensus Cognitive Battery (MCCB) among first episode schizophrenia patients and their biological parents显示文摘背景:精神分裂症的临床表现为特征性的知觉、思维、情感和行为等障碍。认知障碍也是精神分裂症核心症状之一。20世纪70年代早期Gallhofer曾提出过,精神分裂症除有阳性或阴性症状,也存在认知障碍。许多研究表明,精神分裂症的一级亲属中存在遗传易感性。认知障碍不仅急性期存在,维持巩固期也会有。有研究还显示,精神分裂症健康的一级亲属亦存在认知缺陷。但对精神分裂症及其生物学父母的认知特征研究仍缺乏。本研究,我们假设精神分裂症及其生物学父母存在特定的认知功能障碍,拟采用认知功能成套测验共识版(MATRICS Consensus Cognitive Battery,MCCB)中文版,以探讨精神分裂症患者及其生物学父母的认知模式。目的:精神分裂症的认知特征可能受到其生物学父母认知模式的影响。研究旨在描绘精神分裂症患者与其父母之间的功能失调的认知模式。方法:采用认知功能成套测验共识版(MCCB,一种新的测量工具)评估29例首发精神分裂症(符合ICD-10精神分裂症诊断标准,年龄17-45岁),58例精神分裂症患者的生物学父母(年龄40-70岁)和46例健康对照(年龄40-70岁)的认知功能,以探讨精神分裂症患者及其生物学父母之间的认知功能障碍之间的关系。所有数据使用SPSS18.0统计软件进行分析。结果:1)男性精神分裂症患者与其父亲相比在MCCB认知功能测定的6个维度有明显认知缺陷(除社会认知功能外)。女性患者的工作记忆和问题推理能力都低于其母亲。2)患者父亲和健康对照组之间的工作记忆和推理问题也存在显著差异。3)与健康对照组相比,患者母亲在问题推理方面没有明显的差异,但视觉记忆有异常。结论:首发精神分裂症患者及其生物学父母在6个维度存在认知功能障碍。患者父母在工作记忆、问题推理和视觉记忆等方面也存在明显功能障碍。仍需深入研究以揭示首发精神分裂症及其生物学父母存在认知功能障碍的潜在机制。 | Aiai CAO Ting SHEN Haibin LI Chuangxin WU Marita MCCABE David MELLOR Linda BYRNE Jie ZHANG Jia HUANG Daihui PENG Yifeng XU | 2017 | 上海精神医学2017,29,3: | 5 |
| 3 | Atypical features and treatment choices in bipolar disorders:a result of the National Bipolar Mania Pathway Survey in China显示文摘In this study,we examined the point prevalence rate of atypical features in bipolar disorder,and estimated the potential impact of these features on treatment practices in China. Using the atypical features criteria of the Diagnostic and Statistical Manual of the American Psychiatric Association(DSM-IV),we documented the atypical symptoms in 3 906 consecutive participants with bipolar disorder enrolled at 26 psychiatric services across China. We further assessed the association between atypical features and the treatment approaches,including the prescription of antidepressants. The overall point prevalence rate of atypical features was 9.1% among patients with various bipolar disorder subtypes. When the definition was broadened to include atypical features B,the overall rate increased to 11.8%. Interestingly,among patients with the mixed state and remission subtypes,there was a significant difference in the rates of antidepressant medication usage between patients who met and those who did not meet the criteria for atypical features B. These fi ndings indicate a trend of using antidepressants for these two types of patients with atypical features. Further,for both mixed state and remission patients,treatment approaches were related to atypicalfeatures B. Our findings provide evidence to assist clinicians to readily recognize atypical features in bipolar subtypes and can propose treatments based on these diagnoses. | Daihui Peng Ting Shen Linda Byrne Chen Zhang Yueqi Huang Xin Yu Jingping Zhao Marita McCabe David Mellor Yiru Fang | 2015 | Neuroscience Bulletin2015,31,1: | 4 |
| 4 | Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans显示文摘Background:Large numbers of post-deployment U.S.veterans are diagnosed with post-traumatic stress disorder(PTSD)and/or traumatic brain injury(TBI),leading to an urgent need for effective interventions to reduce symptoms and increase veterans’coping.PTSD includes anxiety,flashbacks,and emotional numbing.The symptoms increase health care costs for stress-related illnesses and can make veterans’civilian life difficult.Methods:We used a randomized wait-list controlled design with repeated measures of U.S.military veterans to address our specific aim to test the efficacy of a 6-week therapeutic horseback riding(THR)program for decreasing PTSD symptoms and increasing coping self-efficacy,emotion regulation,social and emotional loneliness.Fiftyseven participants were recruited and 29 enrolled in the randomized trial.They were randomly assigned to either the horse riding group(n=15)or a wait-list control group(n=14).The wait-list control group experienced a 6-week waiting period,while the horse riding group began THR.The wait-list control group began riding after 6 weeks of participating in the control group.Demographic and health history information was obtained from all the participants.PTSD symptoms were measured using the standardized PTSD Checklist-Military Version(PCL-M).The PCL-M as well as other instruments including,The Coping Self Efficacy Scale(CSES),The Difficulties in Emotion Regulation Scale(DERS)and The Social and Emotional Loneliness Scale for Adults-short version(SELSA)were used to access different aspects of individual well-being and the PTSD symptoms.Results:Participants had a statistically significant decrease in PTSD scores after 3 weeks of THR(P≤0.01)as well as a statistically and clinically significant decrease after 6 weeks of THR(P≤0.01).Logistic regression showed that participants had a 66.7%likelihood of having lower PTSD scores at 3 weeks and 87.5%likelihood at 6 weeks.Under the generalized linear model(GLM),our ANOVA findings for the coping self-efficacy,emotion regulation,and social and emotional loneliness did not reach statistical significance.The results for coping self-efficacy and emotion regulation trended in the predicted direction.Results for emotional loneliness were opposite the predicted direction.Logistic regression provided validation that outcome effects were caused by riding longer.Conclusion:The findings suggest that THR may be a clinically effective intervention for alleviating PTSD symptoms in military veterans. | Rebecca A.Johnson David L.Albright James R.Marzolf Jessica L.Bibbo Hayley D.Yaglom Sandra M.Crowder Gretchen K.Carlisle Amy Willard Cynthia L.Russell Karen Grindler Steven Osterlind Marita Wassman Nathan Harms | 2018 | Military Medical Research2018,5,1: | 3 |
| 5 | Assessment of a six-week computer-based remediation program for social cognition in chronic schizophrenia显示文摘 | Linda K BYRNE Lingyi PAN Marita McCABE David MELLOR Yifeng XU | 2015 | 上海精神医学2015,27,5: | 3 |
| 6 | 交际法教学中课文的使用显示文摘课文的使用或许是课堂语言教学的显著特点之一。然而在最近的交际法教学中似乎有一种有害的观点为人所接受,它极大地限止了可供使用的课文类型和依据这类课文所进行的教学活动。下面我们就传统的交际法教学使用课文的三种情况来说明我们的看法。利用课文训练学生运用语言的能力毫无疑问,交际法的要素之一始终是强调不仅让学生操练语言的形式,而且培养他们学会运用语言的方法(Morrow 1981)。人们采用了种类繁多的练习方式。 | Keith Morrow Marita Schocker 周根龙 | 1990 | 外语教学理论与实践1990,,1: | 2 |
| 7 | Secretory phospholipase A2 induces phospholipase Cγ-1 activation and Ca2+mobilization in the human astrocytoma cell line 1321 N1 by a mechanism independent of its catalytic activity显示文摘 | Marita H Maria JB Javier A | 1999 | Biochem Biophys Res Communication1999,260,: | 1 |
| 8 | The effects of EU agricultural policy changes on farmers' risk attitudes 显示文摘 | Koundouri Phoebe Laukkanen Marita Myyr-is ami et | 2009 | European Review of Agricultural Economics2009,36,1: | 1 |
| 9 | Combinatorial modification of multiple lignin traits in trees through multigene cotransformation 显示文摘 | Li L Zhou Y Cheng X Sun J Marita JM Ralph J Chiang VL | 2003 | Proc Natl Acad Sci USA2003,100,8: | 1 |
| 10 | Troglitazone prevents and dexamethasone induced insulin resistance on glycogen synthesis in 3T3 adipocyte 显示文摘 | Anil Kumar K L Marita A R | 2000 | Br J Pharmacol2000,130,: | 1 |
| 11 | Lactoferrin impairs type Ⅲ secretory system function in enteropathogenie Eschericlzia coli显示文摘 | OCHOA T J MARITA N O EBEL F | 2003 | Infect Immun2003,71,9: | 1 |
| 12 | Stable genetic transformation of tomato plastids and expression of a foreign protein in fruit 显示文摘 | STEPHANIE R MARITA H IRVING J B | 2001 | NatBiotechnol2001,19,: | 1 |
| 13 | Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration显示文摘 | Alexandra U. Scherrer Marita K. Sj?berg Alphonse Allangba Mahamadou Traoré Laurent K. Lohourignon Andres B. Tschannen Eliézer K. N'Goran Jürg Utzinger | 2008 | Acta Tropica2008,,3: | 1 |
| 14 | Demonstration of the hypoglycemic action of Momordica charantia in a validated animal model of diabetes显示文摘 | Sarkar S Pranava M Marita R | 1996 | Pharmacol Res1996,33,1: | 1 |
| 15 | Surgical treatment for congenital biliary dilataion, with or without intrahepatic bile duct dilatation 显示文摘 | Hara H Marita S Ishibashi T | 2001 | Hapatogastoenterology2001,48,39: | 1 |
| 16 | Structural and com- positional modifications in lignin of transgenic alfalfa down -regulated in caffeicacid 3 - O - methyhransferase and caffeoyl coenrymeA 3 - O - methyltransferase 显示文摘 | Marita JM Ralph J Haffield RD | 2003 | Phyto- chemistry2003,62,1: | 1 |
| 17 | Sodium hydroxide pretreatment of genetically modified switchgrass for improved enzymatic release of sugar 显示文摘 | Wang ZY Li RY Xu JL JM Marita Hatfield RD Qu R Cheng JJ | 2012 | Bioresour Technol2012,110,: | 1 |
| 18 | Demonstration of the hypoglycemic action of omordica charantia in validated animal model of diabetes显示文摘 | SARKAR S PRANAVA M MARITA R | 1996 | Pharmacol Res1996,33,1: | 1 |
| 19 | Intentions to quit work among care staff working in the aged care sector 显示文摘 | Karantzas Gery C Mellor David McCabe Marita P | 2012 | The Gerontologist2012,52,4: | 1 |
| 20 | Discrimination of Benign and Neoplastic Mucosa with a High-Resolution Microendoscope (HRME) in Head and Neck Cancer显示文摘 | Peter Vila Chan Park Mark Pierce Gregg Goldstein Lauren Levy Vivek Gurudutt Alexandros Polydorides James Godbold Marita Teng Eric Genden Brett Miles Sharmila Anandasabapathy Ann Gillenwater Rebecca Richards-Kortum Andrew Sikora | 2012 | Annals of Surgical Oncology2012,,: | 1 |