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116篇 您的检索式:作者名="MARINA M L"
    题名 作者 年代 出处 被引量
1The presence of ANP in rat peritoneal mast cells显示文摘Atrial natriuretic peptide (ANP) is an important component of the natriuretic peptide system. A great role in many regulatory systems is played by mast cells. Meanwhile involvement of these cells in ANP activity is poorly studied. In this work, we have shown the presence of ANP in rat peritoneal mast cells. Pure fraction of mast cells was obtained by separation of rat peritoneal cells on a Percoll density gradient. By Western blotting, two ANP-immunoreactive proteins of molecular masses of 2.5 kDa and 16.9 kDa were detected in lysates from these mast cells. Electron microscope immunogold labeling has revealed the presence of ANP-immunoreactive material in storage, secreting and released granules of mast cells. Our findings indicate the rat peritoneal mast cells to contain both ANP prohormone and ANP. These both peptides are located in mast cell secretory granules and released by mechanism of degranulation. It is discussed that many mast cell functions might be due to production of natriuretic peptides by these cells.Marina G MARTYNOVA Olga A BYSTROVA Olga M MOISEEVA Anton L EVDONIN Kirill A KONDRATOV Natalja D MEDVEDEVA 2005Cell Research2005,15,10:3
2Personalising pancreas cancer treatment:When tissue is the issue显示文摘The treatment of advanced pancreatic cancer has not moved much beyond single agent gemcitabine until recently when protocols such as FOLFIRINOX(fluorouracil,leucovorin,irinotecan and oxaliplatin)and nab-paclitaxelgemcitabine have demonstrated some improved outcomes.Advances in technology especially in massively parallel genome sequencing has progressed our understanding of the biology of pancreatic cancer especially the candidate signalling pathways that are involved in tumourogenesis and disease course.This has allowed identification of potentially actionable mutations that may be targeted by new biological agents.The heterogeneity of pancreatic cancer makes tumour tissue collection important with the aim of being able to personalise therapies for the individual as opposed to a one size fits all approach to treatment of the condition.This paper reviews the developments in this area of translational research and the ongoing clinical studies that will attempt to move this into the everyday oncology practice.Katrin M Sjoquist Venessa T Chin Lorraine A Chantrill Chelsie O'Connor Chris Hemmings David K Chang Angela Chou Marina Pajic Amber L Johns Adnan M Nagrial Andrew V Biankin Desmond Yip 2014World Journal of Gastroenterology2014,20,24:2
3Comparison of two analytical methods for the determination of organotin compounds in marine organisms显示文摘CAMILLA L MARINA D C EMANUELE M 2009Comptes Rendus Chirnie2009,12,8:1
4Recent advances in the analysis of antibiotics by capillary electrophoresis显示文摘GARCIA-RUIZ C MARINA M L 2006Electrophoresis2006,27,1:1
5Inactivation of Cryptosporidium parvum oocysts with ozone and monochlo- famine at low temperature显示文摘Driedger A M Rennecker J L Marinas B J 2001Water Research2001,35,1:1
6Rapid detection of the addition of soybean proteins to cheese and other dairy products by reversed-phase peffusion chromatography显示文摘GARCIA M C MARINA M L 2006Food Addit Contain2006,23,4:1
7CD4+ CD25+ Foxp3 PD1 - reg- ulatory T ceils in acute and stable relapsing-remitting multiple scle- rosis and their modulation by therapy 显示文摘Marina S Ivana M Renato L 2008FASEB J2008,22,10:1
8Biology and therapeutic advances for pediatric osteosarcoma显示文摘Marina N Gebhardt M Toet L 2004Oncologist2004,9,4:1
9Recent advances in the analysis of antibiotics by CE and CEC显示文摘CASTRO-PUYANA M CREGO A L MARINA M L 2008Electrophorcsis2008,29,1:1
10Analysis of bovine whey protein in soybean dairy-like products by capillary electrophoresis显示文摘Garcia-Ruiz C Torre M Marina M L 1999J Chromatogr A1999,,859:1
11Organochlorine and heavy metal residues in the water/sediment system of the Southeast Regional Park in Madrid, Spain显示文摘Fernandez M Cuesta S Jimenez O Garcia M A Hernandez L M Marina M L Gonzalez M J 2000Chemosphere2000,41,:1
12A capillary electrophoresis-tandem mass spectrometry methodology for the determination of non-protein amino acids in vegetable oils as novel markers for the detection of adulterations in olive oils显示文摘SANCHEZ-HEMfi NDEZ L MARINA M L CREGO A L 2011Journal of Chromatography A2011,1218,30:1
13Identification of native angiotensin-I converting enzyme inhibitory peptides in commercial soybean based infant formulas using HPLC-Q-ToF- MS 显示文摘PUCHALSKA P GARCLA M C MARINA M L 2014Food Chemistry2014,157,:1
14Characterization of en- tomopathogenie nematodes and symbiotic baeteria active against Spodoptera frugiperda ( Lepidoptera : Noctuidae ) and contribution of bacterial urease to the insecticidal effect 显示文摘Juliana M S Marina S D Rodrigo L B 2012Biological Control2012,63,:1
15Biology and therapeutic advances for pediatric osteosarcoma 显示文摘Marina N Gebhardt M Teot L 2004Oncologist2004,9,:1
16Determination by perfusion reversed-phase high-performance liquid chromatography of the soybean protein content of commercial soybeanproducts prepared directly from whole soybeans显示文摘Garca M C Marina M L Torre M 2000J Chromatogr A2000,881,1:1
17Antioxidant activity of methanol extracts obtained from Plantago species 显示文摘MARINA G L CARMEN M N C PETER J H 2005Journal of Agricultural and Food Chemistry2005,53,6:1
18A reversed-phase high-performance liquid chromatographic method for the determination of soya bean proteins in bovine milks显示文摘KRUSA M TORR M MARINA M L 2000Anal Chem2000,72,8:1
19A capillary electrophoresis - tandem mass spectrometry methodology for the determination of non - protein amino acids in vegetable oils'as novel markers for the detection of adulterations in olive oils 显示文摘LAURA S H MARINA M L CREGO A L 2011J Chromatogr A2011,1218,30:1
20Perfusion chromatography: an emergent technique for the analysis of food proteins 显示文摘Garcia M C Marina M L Torte M 2000Chromatogr A2000,880,12:1
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