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| 1 | Invariant natural killer T cells contribute to chronic-plus-binge ethanol-mediated liver injury by promoting hepatic neutrophil infiltration显示文摘嗜中性的渗入是含酒精的 steatohepatitis 的一个特点;然而,内在的机制仍然保持不清楚。我们以前报导 synergistically 喂的 chronic-plus-binge 乙醇导致 neutrophils 的肝的招募,它贡献肝损害。在这份报纸,我们在 chronic-plus-binge 乙醇喂导致调查了不变的自然漂亮 T (iNKT ) 房间的角色肝的嗜中性的渗入和肝损害。野类型并且 iNKT 的二紧张房间缺乏的老鼠(CD1d 缺乏并且 Jα 18-deficient 老鼠) 受到喂的 chronic-plus-binge 乙醇。肝损害和发炎被检验。synergistically 喂的 Chronic-plus-binge 乙醇增加了肝的 iNKT 房间的数字并且导致了他们的激活,与独自的长期的喂或饮酒作乐相比。iNKT 房间缺乏的老鼠被保护免受 chronic-plus-binge 的伤害导致乙醇的肝的嗜中性的渗入和肝损害。而且,显著地喂几基因的肝的表示在野类型的老鼠与发炎和嗜中性的招募联系了的 upregulated 的 chronic-plus-binge 乙醇,而是这些基因的正式就职在 iNKT 被废除房间缺乏的老鼠。重要地,几 cytokines 和 chemokines (例如, MIP-2, MIP-1, IL-4, IL-6 和 osteopontin ) 在嗜中性的渗入包含了在肝的 NKT 房间的 upregulated 从 chronic-plus-binge 被孤立与喂对的老鼠相比的喂乙醇的老鼠。最后,有堵住抗体的 CD1d 的处理,堵住 iNKT 房间激活,部分阻止了 chronic-plus-binge 导致乙醇的肝损害和发炎。喂的 Chronic-plus-binge 乙醇激活肝的 iNKT 房间,它在早含酒精的肝损害的发展起一个关键作用,部分地由释放招募的调停人 neutrophils 到肝,并且这样, iNKT 房间为含酒精的肝的治疗代表一个潜在的治疗学的目标疾病。 | Stephanie Mathews Dechun Feng Igor Maricic Cynthia Ju Vipin Kumar Bin Gao | 2016 | Cellular & Molecular Immunology2016，13，2： | 14 |
| 2 | 应用TaqMan探针进行马铃薯金线虫实时荧光PCR检测技术研究显示文摘马铃薯孢囊线虫是全球性的植物检疫性线虫,亦是我国重点关注的有害生物。针对马铃薯金线虫ITS序列,设计了引物和TaqMan探针,使用15个马铃薯孢囊线虫群体和4个其他孢囊线虫样品进行验证,可高度灵敏地检测单个马铃薯金线虫的孢囊或幼虫,并可进行定量;最高检测灵敏度达到10fg;同时开展了混合样品和未知样品的检测,证明了引物的专化性和TaqMan探针的特异性。该检测方法可自动化检测马铃薯金线虫并进行定量,适合进行标准化的常规检测。 | 葛建军 曹爱新 陈洪俊 Marice Moens | 2009 | 植物保护2009，35，4： | 7 |
| 3 | 马铃薯金线虫的分子检测技术显示文摘本研究通过利用随机引物OPK-4对马铃薯金线虫和白线虫及甜菜胞囊线虫进行RAPD-PCR,供试马铃薯金线中5个群体能产生630bp的特异性的片段,将特异性片段进行测序后发现5个不同来源的马铃薯金线虫产生的特异性片段序列完全一致。根据测定的DNA序列设计出特异性探针,可有效地用于马铃薯金线虫的分子检测。 | 葛建军 刁鹏 陈洪俊 Marice Moens | 2008 | 植物检疫2008，22，1： | 5 |
| 4 | 实时荧光PCR检测马铃薯白线虫技术研究显示文摘马铃薯胞囊线虫是马铃薯上最重要的有害生物之一,也是我国特别关注的重要植物检疫性线虫。针对马铃薯白线虫ITS序列,我们设计了引物和TaqMan探针,使用15种马铃薯胞囊线虫群体和4种其它胞囊线虫样品进行验证,可高度灵敏地检测单个马铃薯白线虫的胞囊或幼虫,最高检测灵敏度达到10fg;同时开展了混合样品和未知样品的检测,证明了引物的专化性和TaqMan探针特异性。该检测方法可自动化检测马铃薯白线虫并进行定量,适合进行标准化的常规检测。 | 葛建军 曹爱新 陈洪俊 Marice Moens | 2009 | 植物检疫2009，23，4： | 4 |
| 5 | Effect of heat treatment on structure and magnetic properties of Fe65.5Cr4Mo4Ga4P12C5B5.5 bulk amorphous alloy显示文摘This study deals with the Fe65.5Cr4Mo4Ga4P12C5B5.5 ferromagnetic bulk amorphous alloy. XRD analysis showed an amorphous structure of the as-cast sample. The same method revealed that, after annealing at 973 K for τ=10 min, the sample displayed a crystalline structure with crystalline phases formed. The crystallization process of the alloy was examined by DTA analysis. It was shown that crystallization took place in the temperature range between 810 K and 860 K with the exo-maximum peak temperature at 846 K with a heating rate of 20 K·min-1. The method also showed that, at temperatures ranging from 753 K to 810 K, the alloy exhibited the properties of supercooled liquids. A correlation between heat-induced structural changes and magnetic properties of the alloy was determined by thermomagnetic measurements. Maximum magnetization M=3.7 Am2·kg-1 of the alloy was reached after its annealing at 733 K for τ=10 min. Upon annealing, the alloy exhibited a relaxed amorphous structure. Annealing the alloy above the crystallization temperature led to a decrease in bulk magnetization. After annealing at 973 K for τ=10 min, the bulk magnetization of the alloy was M'=0.45 Am2·kg-1. Accordingly, after crystallization and formation of new compounds, the magnetization of the alloy was decreased by a factor of about 7.7. The strength of the magnetic field applied during the measurements was H=10 k A·m-1. The samples were tested for changes in the microstructure and hardness of both the amorphous phase and the resulting crystalline phase. | Bratislav Cukic Nebojsa Mitrovic Aleksa Maricic | 2017 | China Foundry2017，14，1： | 4 |
| 6 | Perspectives on new biomarkers in gastric cancer: Diagnostic and prognostic applications显示文摘Gastric cancer is considered one of the most deadly tumors worldwide. Even with the decline in its incidence, the mortality rate of this disease has remained high, mainly due to its late diagnosis and to the lack of precise prognostic markers. The main purpose of this review is to present genetic, epigenetic and proteomic molecular markers that may be used in a diagnostic and prognostic manner and to discuss the pros and cons of each type of marker for improving clinical practice. In this sense, we observed that the use of genetic markers, especially mutations and polymorphisms, should be carefully considered, as they are strongly affected by ethnicity. Proteomic-based markers show promise, but the higher costs of the associated techniques con-tinue to make this approach expensive for routine use. Alternatively, epigenetic markers appear to be very promising, as they can be detected in bodily fluids as well as tissues. However, such markers must be used carefully because epigenetic changes may occur due to environmental factors and aging. Despite the advances in technology and its access, to date, there are few defined biomarkers of prognostic and diagnostic use for gastric tumors. Therefore, the use of a panel of several approaches(genetic, epigenetic and proteomic) should be considered the best alternative for clinical practice. | Danilo do Rosário Pinheiro Wallax Augusto Silva Ferreira Mariceli Baia Leo Barros Mariana Diniz Araújo Symara Rodrigues-Antunes Bárbara do Nascimento Borges | 2014 | World Journal of Gastroenterology2014，20，33： | 4 |
| 7 | Prognostic value of endothelial dysfunction in type 1 diabetes mellitus显示文摘Patients with diabetes mellitus are at high risk of developing atherosclerosis, associated with higher rates of micro and macro vascular involvement such as coronary artery disease and renal disease. The role of hyperglycemia to induce synthesis of reactive oxygen species by the oxidation of glucose, leading to an increased production of advanced glycosylation end products, as well as inflammation and oxidative stress has been proposed as a possible mechanism in the pathogenesis of endothelial dysfunction(ED). The interaction between C-peptide- the connecting segment of pro-insulin-and nitric oxide in vasodilation is also discussed. Therefore, endothelial dysfunction has been identified as an early marker of vascular disorder in type 1 and type 2 diabetes mellitus. In some other diseases, ED has been considered an independent predictor of vascular disease, regardless of the method used. Studies have demonstrated the importance of endothelial dysfunction as an useful tool for identifying the risk of vascular complications in patients with type 1 diabetes mellitus, particularly as regards to renal impairment. The aim of this review is to clarify the prognostic value of endothelial dysfunction as a marker of vascular disease in these subjects. | Ana Marice Ladeia Raphael Ribeiro Sampaio Maiara CostaHita Luis F Adan | 2014 | World Journal of Diabetes2014，5，5： | 2 |
| 8 | Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas显示文摘 | Santos RAS Simoese Silva AC Maric C | 2003 | Proc Natl Acad Sci USA2003，100，： | 1 |
| 9 | Match ana- lyses of Australian professional soccer players 显示文摘 | WITHERS R T MARICIC ZWASILEWSKI | 1982 | J Human Move Stud1982，，8： | 1 |
| 10 | Formation of N20 in the photoly- sis/photoexcitation of NO, N20 and air 显示文摘 | Maric D Burrows J P | 1992 | Journal of Photochemistry and Photobiology A: Chemistry1992，66，3： | 1 |
| 11 | Fear of Success the Construction and Validation of a Measuring Instrument 显示文摘 | Marice Pappo | 1983 | Journal of Personality Assessment1983，47，1： | 1 |
| 12 | Estrogens and the diabetic kidney 显示文摘 | Maric C Sullivan S | 2008 | Gend Med2008，5，： | 1 |
| 13 | Ni-SDC Anode for Mediumtemperature Solid Oxide Fuel Cell with Lanthanum Gallate Electrolyte显示文摘 | Ohara S Maric R | 1999 | J Power Sources1999，83，： | 1 |
| 14 | Psychiatric and neuropsychological changes in growth hormone-deficient patients after traumatic brain injury in response to growth hormone therapy显示文摘 | Maric NP Doknic M Pavlovic D | 2010 | J Endocrinol Invest2010，33，11： | 1 |
| 15 | A - kinase anchoring protein - Lbc promotes pro -fibrotic signaling in cardiac fibmblasts显示文摘 | Cavin S Maric D Diviani D | 2014 | Biochim Bio- phys Acta2014，1843，2： | 1 |
| 16 | Powder prepared by spray pyrolysis as an electrode material for solid oxide fuel cells显示文摘 | MARIC R FUKUI T OHARA S | 2000 | J Mater Sci2000，35，3： | 1 |
| 17 | Age- and Region-Dependent Changes in Human Lumbar Vertebral Bone: A Histomorphometric Study显示文摘 | Olga Cvijanovic Dragica Bobinac Sanja Zoricic Zdenko Ostojic Ivana Maric Zeljka Crncevic-Orlic Ines Kristofic Ljerka Ostojic | 2004 | Spine2004，，21： | 1 |
| 18 | Expression of bone morphogenetic proteins and cartilage-derived morphogenetic proteins during osteophyte formation in humans 显示文摘 | Maric I Bobinac D Vukicevic S | 2003 | J Anat2003，202，3： | 1 |
| 19 | Geomerrical parameter estimation for industrial manipulator ising two-step estimation schemes 显示文摘 | Maric P | 1999 | Journal of Intelligent and Robotic Systems1999，24，2： | 1 |
| 20 | High performance electrodes for reduced temperature SOFCs with doped lanthanum gallate electrolyte显示文摘 | Ohara S Maric R Zhang X | 2000 | J Power Sources2000，86，： | 1 |
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