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1739篇 您的检索式:作者名="MANNING M"
    题名 作者 年代 出处 被引量
1表皮通透屏障功能与表皮CD44表达关系的研究显示文摘目的:研究表皮通透屏障功能破坏后表皮CD44的表达。方法:外用胶带破坏裸鼠躯干部表皮通透屏障功能,分别于30min、1h、3h、6h、24h和48h后取皮肤标本,用免疫组化的方法观察CD44在表皮的表达。结果:在表皮通透屏障功能破坏后30min,表皮CD44的表达明显上调;1h和3h后,恢复至正常水平;6h后,表皮CD44的表达又明显增强,并持续到48h;人为地纠正屏障功能(封包)对表皮CD44的表达没有明显影响。结论:表皮通透屏障功能破坏后,表皮CD44的表达增强,其表达的改变与屏障功能本身无显著相关性。Mona Man 吕成志 辛淑君 Kenneth R Feingold Peter M Elias 蔄茂强 2008临床皮肤科杂志2008,37,7:5
2Effect of polyethylene glycol on electrochemically deposited trivalent chromium layers显示文摘The structural characteristics of the trivalent chromium deposits and their interfacial behavior in the plating solution with and without polyethylene glycol molecules were observed by using various electrochemical methods such as cyclic voltammetry,open circuit potential transition,electrochemical impedance spectroscopy,scanning electron microscopy and X-ray photoelectron spectrometry.It is shown that the polyethylene glycol molecules make the reductive current density lower in the trivalent chromium plating system and promote a hydrogen evolution reaction through their adsorption on the electrode surface.And the trivalent chromium layer formed from the polyethylene glycol-containing solution has somewhat higher density of cracks on its surface and results in a lower film resistance,lower polarization resistance,and higher capacitance in a corrosive atmosphere.It is also revealed that the formation of chromium carbide layer is facilitated in the presence of polyethylene glycol,which means easier electrochemical codeposition of chromium and carbon,not single chromium deposition.Joo-Yul LEE Man KI M Sik-Chol KWON 2009中国有色金属学会会刊:英文版2009,19,4:5
3TLR2和TLR4在不同皮炎模型皮肤的表达显示文摘目的研究Toll样受体2(TLR2)和TLR4在不同皮肤炎症的表达是否有区别。方法分别外涂弗博酯、oxazolone或胶带法于裸鼠躯干部制作皮炎模型。用免疫组化的方法观察TLR2和TLR4在真皮和表皮的表达。结果皮炎上调TLR2在表皮的表达及TLR4在真皮的表达;分别外涂弗博酯及oxazolone所诱发的皮炎中炎症细胞浸润较为明显,其TLR2和TLR4的表达增强也较明显;胶带法所诱导的皮炎中其炎症细胞浸润较轻,TLR2和TLR4的表达也较轻。结论皮炎分别上调皮肤TLR2和TLR4在真皮和表皮的表达;TLR2表达增强的程度与炎症程度有关。吕成志 Mona Man 张信江 Kenneth R Feingold Peter M Elias 蔺茂强 2009中国皮肤性病学杂志2009,23,7:4
4The European registry of quality outcomes for cataract and refractive surgery(EUREQUO):a database study of trends in volumes,surgical techniques and outcomes of refractive surgery显示文摘Background:A European web-based registry for refractive surgery was established in 2008;The European Registry of Quality Outcomes for Cataract and Refractive Surgery(EUREQUO).The aim of the registry was to improve treatment and standards of care for refractive surgery.Further aims were to offer a tool for benchmarking by establishing a reference database and for surgeons to enter and analyze their own outcomes.The purpose of this study was to characterize the registry and analyze the data collected during its first decade.Methods:The characteristics of the web-based registry are described.Data collected from February 4^(th) 2004 until June 30th 2014 are included in the analysis.The database is analyzed in terms of surgical technique,indications for surgery,complications,and refractive and visual outcomes.Results:Data have been reported from 47 centers in 14 countries until mid-2014.About 4,000 procedures were reported annually.The most frequent procedure was laser-assisted in-situ keratomileusis(LASIK)with 11697 reported surgeries.Over time in the database,LASIK declined(p<0.001)while photorefractive keratectomy(PRK)and refractive lens exchange(RLE)increased(p<0.001 for both procedures).The indications for surgery,in terms of preoperative refraction and age,were stable over time,for all types of procedures.Surgical complications were reported infrequently and with a well-known relationship to the type of surgical procedure.The reported refractive outcomes were good.The visual outcomes indicate a significant increase of visual acuity after high myopia treatment by phakic intraocular lens in the anterior(phakic IOL AC)and the posterior(phakic IOL PC)chamber and a poorer visual outcome,after both myopia and hyperopia treatment,by epithelial LASIK(Epi-LASIK).Conclusions:We describe the establishment of a European registry for refractive surgery.The database increases at a rate of approximately 4000 refractive procedures per year.The most frequent procedure is LASIK,but both PRK and RLE are an increasing part of the reported procedures.The indications for surgery have been stable over time.Surgical complications and visual outcome vary,depending on the type of surgery.Mats Lundström Sonia Manning Peter Barry Ulf Stenevi Ype Henry Paul Rosen 2015Eye and Vision2015,2,1:3
5National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales.Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser 2021Forest Ecosystems2021,8,1:2
6Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats显示文摘现在的实验被设计与 aging.Methods 在内皮细胞层依赖者收缩学习变化: 老鼠有或没有内皮细胞层的 20 星期、 1 岁的老鼠的大腿骨的动脉在机关房间被推迟记录等轴的紧张。在内皮细胞层的导出氧的自由基的生产用共焦的显微镜学与 2',7'-dichlorodihydrofluorescein 乙酰乙酸盐(DCF ) 被测量。蛋白质存在被西方的 blotting.Results 决定:在从1岁的老鼠的动脉,到 A23187 的内皮细胞层依赖者松驰被减少,但是内皮细胞层依赖者收缩到 A23187 (面对N^(终止) -nitro-L-arginine 甲基酉旨水疗院氯化物[L名字;氮的氧化物 synthase 的一个禁止者])有老化的被扩充的、示威内皮机能障碍。消炎痛使回答正常化,建议那一个 cyclooxygenase (艇长) 依赖者收缩在老化是突出的。内皮细胞层依赖者收缩被 terutroban (一块 thromboxane-prostanoid 受体) 也阻止,证实脉管的光滑的 muscle.Valeryl 水杨酸盐上的 thromboxane-prostanoid 受体的激活,显示 COX-1 和 COX-2 被包含并且 NS-398 (COX-1 和 COX-2 的优先的禁止者,分别地) 部分减少了反应。西方的弄污证实了起来在 1 岁的老鼠的动脉的两 isoforms 的规定。面对 L 名字, A23187 在内皮细胞层增加了 DCF 荧光,证明导出氧的自由基的生产贡献内皮细胞层依赖者收缩。过氧化氢酶的活动与 1 岁的老鼠的内皮细胞层在动脉被减少,显示那过氧化氢是在变老的 endothelium.Conclusion 的增加的氧化应力的可能的调停人: 内皮细胞层依赖者收缩与老化被扩充。氧化应力加强反应,和 COX-1 和 COX-2 被包含。Yi SHI Ricky YK MAN Paul M VANHOUTTE 2008Acta Pharmacologica Sinica2008,29,2:2
7Heuristic solutions for the multiple-choice multi-dimension knapsack problem显示文摘Akbar M M Manning E G Shoja G C 2001Lecture Notes in Computer Science2001,2074,2:1
8Inhibition of cholesterol and sphingolipid synthesis causes pardoxical effects on permeability harrier homeostasis显示文摘Man M Feingold KR Elias PM 1993The Journal of Investigative Dermatology1993,101,2:1
9Environmentally decoupled sds-wave Josephson junctions for quantum computing显示文摘Ioffe L B Geshkenbein V B Feigel'man M V 1999Nature(London)1999,398,:1
10Characteristics, apa tire-forming ability and corrosion resistance of NiTi surface modified by AC anodization 显示文摘WONG M H CHENG F T MAN H C 2007Appl Surface Sci2007,253,18:1
11Inhibition of cholesterol and sphingolipid synthesis causes para- doxical effects on permeability barrier homeostasis 显示文摘Man Maoqiang Feingold K R Elias P M 1993The Journal of Investigative Dermatology1993,101,2:1
12Occurrence,predictors and clinical significance of autonomic neuropathy in NIDDM,ten year follow-up from the diagnosis显示文摘TOYRY J P NISKANEN L K MANLY SAARI M J 1996Diabetes1996,45,:1
13Synthesis and some used of receptor -specific agonists and antagonists of vasopressin and oxytocin显示文摘Manning M Sawyer WH 1993J Recept Res1993,13,4:1
14An introduction to contingent (closed-loop) brain electrical stimulation for sei- zure blockage, to ultra-short-term clinical trials, and to multi dimensional statistical analysis of therapeutic efficacy 显示文摘OSORIO I FREI M G MANLY B F 2001J Clin Neurophysiol2001,18,6:1
15The effect of excimer laser surface treatment on the pitting corrosion fatigue behaviour of alnminium alloy 7075 显示文摘Chan C P Yue T M Man H C 2003Journal of Materials Science2003,15,12:1
16Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells显示文摘FRIEDMAN R L MANLY S P MCMAHON M 1984Cell1984,38,3:1
17Urokinase inereases the content and activity of matrix metalloproteinase-2 and 9during in vivo constrictive arterial remodeling显示文摘Solomatina M A Plekhanova O S Man'shikova M Y 2005Bull Exp Bio Med2005,139,:1
18The antithrombotic effect of aprotinin:actions mediated via the protease-activated receptorl显示文摘 Manning R Laffan M 2000J Thorac Cardiovasc Surg2000,120,:1
19Determination of munition components in water by resin adsorption and high performance liquid chromatography-electrochemical detection显示文摘 Manning D L Harvey R W 1984J Chromatogr1984,302,:1
20NF-κB is activated during acute inflammation in vivo in association with molecule gene expression and leukocyte recruitment显示文摘 BELL F P ROSENBLOOM J G 1995J Inflamm1995,45,4:1
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