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| 1 | Intercellular Trogocytosis Plays an Important Role in Modulation of Immune Responses显示文摘Intercellular communication is an important means of molecular information transfer through exchange of membrane proteins from cells to cells. Advent of the latest analytical and imaging tools has allowed us to enhance our understanding of the cellular communication through the intercellular exchange of intact membrane patches,also called trogocytosis,which is a ubiquitous phenomenon. Immune responses against pathogens or any foreign antigens require fine immune regulation,where cellular communications are mediated by either soluble or cell surface molecules. It has been demonstrated that the membrane molecule transfer between immune cells such as dendritic and T cells can be derived through internalization/recycling pathway,dissociation-associated pathway,uptake of exosomes and membrane nanotube formations. Recent evidence implicates the trogocytosis as an important mechanism of the immune system to modulate immune responses. Exchange of membrane molecules/ antigens between immune cells has been observed for a long time,but the mechanisms and functional consequences of these transfers remain unclear. In this review,we discuss the possible mechanisms of trogocytosis and its physiological relevance to immune system,with special reference to T cells and the stimulatory or suppressive immune responses derived from T cells with acquired dendritic cell membrane molecules. | Khawaja Ashfaque Ahmed Manjunatha Ankathatti Munegowda Jim Xiang | 2008 | Cellular & Molecular Immunology2008，5，4： | 6 |
| 2 | Impact of heat shock on heat shock proteins expression, biological and commercial traits of Bombyx mori显示文摘我们报导新二化性蚕, Bombyx 粗腐殖质 i strainsNB_4D_2, KSO_1, NP_2, CSR_2 和 CSR_4 和热的微分表示的 thermotolerance 在不同中间形态震惊蛋白质。蚕 larva 的不同中间形态被使遭到在 35 ° C, 40 ° C 和 45 ° C 加热吃惊 2 小时恢复跟随的 2 个小时。热吃惊蛋白质被热吃惊的 SDS-PAGE.The 影响在茧的商业特点上分析被后面的不同策略在控制上以获得的 thermotolerance 分析。比较地, NP_2 比另外的种类展出了 bettersurvivability。当幼虫的开发在第一中间形态 >
秒中间形态 >
的顺序继续,加热吃惊的抵抗被增加第三中间形态 >
第四中间形态 >
在所有蚕种类的第五中间形态。热吃惊蛋白质的表示在不同中间形态变化。在第一,第二和第三中间形态,在第四中间形态的 84 kDa 和 84, 62, 60, 47 和 33 kDa 的 90 kDa 在第五中间形态加热吃惊蛋白质响应热吃惊被观察。对应于不同阶段的商业特点上的热吃惊的相对影响在所有紧张是重要的。InNB_4D_2,茧和壳重量显著地分别地在控制上增加了到 17.52% 和 19.44% 。热为评估和进化 ofthermotolerant 蚕紧张作为分子的标记震惊蛋白质因为热带被讨论。 | VASUDHA B. CHAVADI APARNA H. SOSALEGOWDA MANJUNATHA H.B OREGOWDA | 2006 | Insect Science2006，13，4： | 5 |
| 3 | Hypolipidemic and Antioxidant Effects of Dietary Curcumin and Capsaicin in Induced Hypercholesterolemic Rats显示文摘 | H. Manjunatha K. Srinivasan | 2007 | Lipids2007，，12： | 2 |
| 4 | Lung gene therapydHow to capture illumination from the light already present in the tunnel显示文摘Gene therapy has been considered as the most ideal medical intervention for genetic diseases because it is intended to target the cause of diseases instead of disease symptoms.Availability of techniques for identification of genetic mutations and for in vitro manipulation of genes makes it practical and attractive.After the initial hype in 1990s and later disappointments in clinical trials formore than a decade,light has finally come into the tunnel in recent years,especially in the field of eye gene therapy where it has taken big strides.Clinical trials in gene therapy for retinal degenerative diseases such as Leber’s congenital amaurosis(LCA)and choroideremia demonstrated clear therapeutic efficacies without apparent side effects.Although these successful examples are still rare and sporadic in the field,they provide the proof of concept for harnessing the power of gene therapy to treat genetic diseases and to modernize our medication.In addition,those success stories illuminate the path for the development of gene therapy treating other genetic diseases.Because of the differences in target organs and cells,distinct barriers to gene delivery exist in gene therapy for each genetic disease.It is not feasible for authors to review the current development in the entire field.Thus,in this article,we will focus onwhatwe can learn from the current success in gene therapy for retinal degenerative diseases to speed up the gene therapy development for lung diseases,such as cystic fibrosis. | Emily Xia Manjunatha Ankathatti Munegowda Huibi Cao Jim Hu | 2014 | Genes & Diseases2014，1，1： | 2 |
| 5 | A Highly Sensitive Spectrophotometric Method for the Determination of Some Phenothiazine Antipsychotics Using Chloramine-T and Indigocarmine 显示文摘 | Basavaiah K Manjunatha S J | 2001 | Anal Sci2001，17，： | 2 |
| 6 | Generalized Inverses of Matrices Over a Commutative Ring显示文摘 | MANJUNATHA K PRASAD | 1994 | Linear AlgebraAppl1994，211，： | 1 |
| 7 | Kinetics of moisture loss and oil uptake during deep fat frying of Gethi(Dioscorea kamoonensis Kunth)strips显示文摘 | MANJUNATHA S S RAVI N NEGIP S | 2012 | Journal of Food Science and Technology2012，51，11： | 1 |
| 8 | Malignant potential in a Brunner's gland hamartoma显示文摘 | Brookes MJ Manjunatha S Allen CA | 2003 | Postgrand Med J2003，79，： | 1 |
| 9 | The effect of pH, sucrose and ammonium sulphate concentrations on the production of bacterial cellulose (Nata-de-coco) by Acetobacter xylinum显示文摘 | Jagannath A Kalaiselvan A Manjunatha S S | 2008 | World Journal of Microbiology and Biotechnology2008，24，11： | 1 |
| 10 | Follicular fluid concentrations of glucose,lactate and pyruvate in buffalo and sheep,and their effects on cultured oocytes,granulosa and cumulus cells显示文摘 | NANDI S GIRISH KUMAR V MANJUNATHA B M | 2008 | Theriogenology2008，69，2： | 1 |
| 11 | PA-824 kills nonreplicating mycobacterium tuberculosis by intracellular NO release显示文摘 | Singh R Manjunatha U Boshoff HIM | 2008 | Science2008，322，5906： | 1 |
| 12 | Regulation of ad- iponectin secretion by soy isoflavones has implication for endocrine function of the testis 显示文摘 | Andrew P Manjunatha K N Elaine S C | 2012 | Original Research Article Toxicology Letters2012，209，： | 1 |
| 13 | Nitric oxide counters ethylene effects on ripening fruits显示文摘 | MANJUNATHA G GUPTA KJ LOKESH V MUR L A NEEL-WARNE B | 2012 | Plant Signaling & Behavior2012，7，4： | 1 |
| 14 | Nitric oxide in fruit ripening : trends and opportunities 显示文摘 | Manjunatha G Lokesh V Neelwarne B | 2010 | Biotechnology Advances2010，28，4： | 1 |
| 15 | Calcineurin inhibitors in pediatric atopic dermatitis a review of current evidence显示文摘 | Manjunatha K Magdalene AD | 2011 | Am J Clin Dermatol2011，1，12： | 1 |
| 16 | A colorimetric aptasensor for the diagnosis of malaria based on cationic polymers and gold nanoparticles<!-- Aptamer-based biosensor -->显示文摘 | Weejeong Jeon Seonghwan Lee Manjunatha DH Changill Ban | 2013 | Analytical Biochemistry2013，，1： | 1 |
| 17 | PA 824 kills nonrepli- caring Myeobacterium tuberculosis by intracellular NO release 显示文摘 | Singh R Manjunatha U Boshoff HI | 2008 | Science2008，322，5906： | 1 |
| 18 | Effects of tannins from geum japonicum显示文摘 | Dong H Chen S X Manjunatha K R | 1998 | Journal of Natural Products1998，61，： | 1 |
| 19 | Nitric oxide counters ethylene effects on ripening fruits 显示文摘 | Manjunatha G Gupta K J Lokesh V | 2012 | Plant Signaling & Behavior2012，7，4： | 1 |
| 20 | Hypolipidemic and antioxi- dant effects of curcumin and capsaiein in high-fat-fed rats 显示文摘 | MANJUNATHA H SRINIVASAN K | 2007 | Can J Physiol Pharmacol2007，85，6： | 1 |
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