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101篇 您的检索式:作者名="MAL N"
    题名 作者 年代 出处 被引量
1Efficacy of bevacizumab-containing chemotherapy in metastatic colorectal cancer and CXCL5 expression: Six case reports显示文摘BACKGROUND In metastatic colorectal cancer(mCRC),the anti-vascular endothelial growth factor drug bevacizumab(BVZ)plus chemotherapy significantly improves progression-free survival compared to chemotherapy(CT)alone.This benefit is not,however,observed in all patients.While increased chemokine CXCL5 gene expression promoting angiogenesis has been proposed as a prognostic mCRC biomarker,few studies have examined its relationship with drug efficacy.This study sought to analyze tumor CXCL5 gene expression in six patients with different efficacy of BVZ-containing CT in terms of the tumor response to treatment.CASE SUMMARY We report six cases of stage IV KRAS-mutated mCRC.Patients were given first line treatment with BVZ-containing chemotherapy in University Hospital of Fuenlabrada.The six patients differed in terms of primary tumor location(right/left side),tumor burden(mostly hepatic and peritoneal disease)and clinical disease course.Before treatment onset,total RNA was isolated from paraffinated tumor biopsy specimens and CXCL5 gene expression quantified through conventional RT-qPCR procedures.Our main finding was that CXCL5 expression levels were several times higher in three patients with lower progression free survival(under 6 mo)from the start of treatment.CONCLUSION A higher expression of CXCL5 was observed in the three patients showing worse tumor response to treatment.Apolonia Novillo María Gaibar Alicia Romero-Lorca María Fuencisla Gilsanz Laura Beltrán Miguel Galán Beatriz Antón Diego Malón Amalia Moreno Ana Fernández-Santander 2020World Journal of Gastroenterology2020,26,16:2
2SDF-1 expression by mesenchymal stem cel s results in trophic support of cardiac myocytes after myocardial infarction显示文摘Zhang M Mal N Kiedrowski M 0,,12:1
3SDF-1 recruits cardiac stem cell-like cells that depolarize in vivo显示文摘Unzek S Zhang M Mal N 2007Cell Transplant2007,16,9:1
4Stem cell therapy enhances electrical viability in myocardial infarction显示文摘Mills WR Mal N Kiedroski MJ 2007Mol Cell Cardio2007,42,2:1
5查看详情显示文摘Sasidharan M Mal N K Bhaumik A 0,,03:1
6Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica显示文摘MAL N K FUJIWARA M TANAKA Y 2003Nature2003,421,6921:1
7Monoeyte ehemotactic protein-3 is amyocardial mesenchymal stem eell homing faetor 显示文摘Sehenk S Mal N Finan A 2007Stem Cells2007,25,1:1
8Monocyte chemotactic protein- 3 is a myocardial mesenchymal stem cell homing factor 显示文摘Schenk S Mal N Finan A 2007Stem Cells2007,25,1:1
9Photo-switched storage and release of guest molecules in the pore void of coumarin-modified MCM-41显示文摘MAL N K FUJIWARA M TANAKA Y 2003Chem Mater2003,15,17:1
10Response of okra to dripirrigation under mulch and non-mulch conditions显示文摘Tiwari K N Mal P K Singh R M Chattopadhyay A 1998Agricultural Water Management1998,38,2:1
11Stem cells in cardiovascular disease:methods and protocols显示文摘Penn MS Mal N 2006Methods Mol Med2006,129,:1
12Microporous niobium phosphates and catalytic properties prepared by a supramolecular templating mechanism显示文摘Mal N K Bhaumik A Kumar P 2003Chem Commun2003,,7:1
13Titanium-rich highly ordered mesoporous silica synthesized by using a mixed surfactant system 显示文摘Chandra D Mal N K Mukherjee M 2006J Solid State Chem2006,179,6:1
14SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction显示文摘Zhang M Mal N Kiedrowski M 0,,:1
15SDF- 1α expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction 显示文摘Zhang M Mal N Kiedrowski M 2007FASEB J2007,21,12:1
16SDF- 1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction显示文摘Zhang M Mal N Kiedrowski M 2007Faseb J2007,21,12:1
17Modified TS-1 for shape selective phenol hydroxylation to hydroquinone显示文摘MAL N K KUMAR P SASIDHARAN M 2004Studies in Surface Science and Catalysis2004,154,3:1
18Hip fracture management,before and beyond surgery and medication:a synthesis of the evidence显示文摘O'Mal ey NT Blauth M Suhm N 0,,11:1
19Electrophysiological consequence of skeletal myoblast transplantation in normal and infarcted canine myocardium显示文摘Fours K Fernandes B Mal N 2006Heart Rhythm2006,3,4:1
20Rainwater conservation and recycling by optimal size on-farm reservoir显示文摘Balram Panigrahi Sudhindra N Panda Bimal Chandra Mal 2007Resources Conservation and Recycling2007,50,4:1
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