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| 1 | Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy显示文摘Acute appendicitis(AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy(LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time. However, this technique may have some advantages for avoiding unnecessary extended resection in patients with an appendiceal mass. Nonoperative management of AA may be tolerated only in children. Postoperative complications increase according to the patient's factors, and temporal avoidance of emergent general anesthesia may be beneficial for high-risk patients. The surgeon's skill and cooperation of the hospital are important for successful LA. Delaying appendectomy for less than 24 h from diagnosis is safe. Additionally, a semi-elective manner(i.e., LA within 24 h after onset of symptoms) may be paradoxically acceptable, according to the factors of the patient, physician, and institution. Prompt LA is mandatory for AA. Fortunately, the Japanese government uses a universal health insurance system, which covers LA. | tomohide hori takafumi machimoto yoshio kadokawa toshiyuki hata tatsuo ito shigeru kato daiki yasukawa yuki aisu yusuke kimura maho sasaki yuichi takamatsu taku kitano shigeo hisamori tsunehiro yoshimura | 2017 | World Journal of Gastroenterology2017，23，32： | 18 |
| 2 | HsfAld, a Protein Identified via FOX Hunting Using Thellungiella salsuginea cDNAs Improves Heat Tolerance by Regulating Heat-Stress-Responsive Gene Expression显示文摘Thellungiella salsuginea (先前 T。halophila ) ,种仔细与 Arabidopsis (Arabidopsis thaliana ) 有关,是容忍的不仅高腌层次,而且到寒心,结冰,并且臭氧。这里,我们报导那 T。salsuginea 也比 Arabidopsis 显示出更大的热忍耐。我们识别了 T。作为基因,那能授与的 salsuginea HsfA1d (TsHsfA1d ) 在 Arabidopsis 上标记热忍耐。TsHsfA1d 经由全身的 cDNA 被识别从许多 heat-stress-related T 之中狩猎的过去表示的基因(狐狸) 。salsuginea cDNAs。转基因的 Arabidopsis overexpressing TsHsfA1d 在正常生长温度下面在 Arabidopsis AtHsfA1 regulon 显示出许多基因的组成的起来规定。在 Arabidopsis 叶肉原物, TsHsfA1d 在原子核和细胞质是局部性的。TsHsfA1d 也与 AtHSP90 交往了,它否定地由在细胞质形成 HsfA1HSP90 建筑群调整 AtHsfA1s。TsHsfA1d 的部分原子本地化在正常温度在转基因的植物导致了 AtHsfA1d regulon 的表示,是可能的。我们也发现转基因的 Arabidopsis 植物 overexpressing AtHsfA1d 比野类型的植物更热容忍、起来调整 HsfA1d regulon 的表示在 TsHsfA1d-overexpressing 植物被观察。我们建议 TsHsfA1d 和 AtHsfA1d 的产品作为 Arabidopsis 热压力反应的积极管理者工作并且将为在另外的植物的热压力忍耐的改进有用。 | Yukari Higashi Naohiko Ohama Tomoko Ishikawa Taku Katori Ayaka Shimura Kazuya Kusakabe Kazuko Yamaguchi-Shinozaki Junko Ishida Maho Tanaka Motoaki Seki Kazuo Shinozaki Yoichi Sakata Takahisa Hayashi Teruaki Taji | 2013 | Molecular Plant2013，6，2： | 5 |
| 3 | Protocol for laparoscopic cholecystectomy: Is it rocket science?显示文摘Laparoscopic cholecystectomy(LC) does not require advanced techniques, and its performance has therefore rapidly spread worldwide. However, the rate of biliary injuries has not decreased. The concept of the critical view of safety(CVS) was first documented two decades ago. Unexpected injuries are principally due to misidentification of human factors. The surgeon's assumption is a major cause of misidentification, and a high level of experience alone is not sufficient for successful LC. We herein describe tips and pitfalls of LC in detail and discuss various technical considerations.Finally, based on a review of important papers and our own experience, we summarize the following mandatory protocol for safe LC:(1) consideration that a high level of experience alone is not enough;(2) recognition of the plateau involving the common hepatic duct and hepatic hilum;(3) blunt dissection until CVS exposure;(4) Calot's triangle clearance in the overhead view;(5) Calot's triangle clearance in the view from underneath;(6) dissection of the posterior right side of Calot's triangle;(7) removal of the gallbladder body; and(8) positive CVS exposure. We believe that adherence to this protocol will ensure successful and beneficial LC worldwide, even in patients with inflammatory changes and rare anatomies. | Tomohide Hori Fumitaka Oike Hiroaki Furuyama Takafumi Machimoto Yoshio Kadokawa Toshiyuki Hata Shigeru Kato Daiki Yasukawa Yuki Aisu Maho Sasaki Yusuke Kimura Yuichiro Takamatsu Masato Naito Masaya Nakauchi Takahiro Tanaka Daigo Gunji Kiyokuni Nakamura Kiyoko Sato Masahiro Mizuno Taku Iida Shintaro Yagi Shinji Uemoto Tsunehiro Yoshimura | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 4 | Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism显示文摘 | Yoshiyuki Kimura Maho Sumiyoshi Kei-ichi Samukawa Noriko Satake Masahiro Sakanaka | 2008 | European Journal of Pharmacology2008，，2： | 2 |
| 5 | oxidative stress induces intracellular accumulation of amyloid beta-protein in human neuroblastonma cells显示文摘 | Misonon H Maho MK Yasuo I | 2000 | Biochem2000，，39： | 1 |
| 6 | Avain β-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus 显示文摘 | THOUZEAU C MAHO Y L FROGET G | 2003 | J Biol Chem2003，278，51： | 1 |
| 7 | Evaluation of Humoral Immunity to Mycobacterium tuberculosis -Specific Antigens for Correlation with Clinical Status and Effective Vaccine Development显示文摘 | Mamiko Niki Maho Suzukawa Shunsuke Akashi Hideaki Nagai Ken Ohta Manabu Inoue Makoto Niki Yukihiro Kaneko Kozo Morimoto Atsuyuki Kurashima Seigo Kitada Sohkichi Matsumoto Koichi Suzuki Yoshihiko Hoshino Pedro A. Reche | 2015 | Journal of Immunology Research2015，，： | 1 |
| 8 | Avain βdefensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus 显示文摘 | THOUZEAU C MAHO Y L FROGET G | 2003 | J Biol Chem2003，278，51： | 1 |
| 9 | Effects of various E/euthero- coccus senticosus cortex on swimming time, natural killer activity and cor- ticosterone level in forced swimming stressed mice显示文摘 | YOSHIYUKI KIMURA MAHO SUMIYOSHI | 2004 | Journal of Ethno- pharmacology2004，95，23： | 1 |
| 10 | A new Spanish family with CADASIL associated with 346C>T mutation of NOTCH3 gene显示文摘 | Avila A Bello J Maho P | 2007 | Neurologia2007，22，7： | 1 |
| 11 | A new spanish family with CADA- SIL associated with 346C > T mutation of NOTCH3 gene 显示文摘 | Avila A Bello J Maho P | 2007 | Neu- rologia2007，22，： | 1 |
| 12 | Effects of ginseng saponins isolated from red ginseng on ultraviolet B-induced skinaging in hairless mice显示文摘 | Young GonKim Maho Sumiyoshi Masahiro Sakanaka | 2009 | European Journal of Pharmacology2009，602，： | 1 |
| 13 | Spheniscins: avian - defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus 显示文摘 | THOUZEAU C MAHO Y L FROGET G | 2003 | Biol Chem2003，278，51： | 1 |
| 14 | Neuronal plasticity induced by fear conditioning is expressed during paradoxical sleep: evidence fromsim ultaneous recordings in the lateral amygdala and the medial geniculate in rats显示文摘 | Hennevin E Maho C Hars B | 1998 | Behav Neurosei1998，112，： | 1 |
| 15 | Effect of surface pre-treatment on durability of resin-based cements bonded to titanium显示文摘 | TSUCHIMOTO YOUHEI YOSHIDA YASUHIRO TAKEUCHI MAHO | 2006 | Dental Materials2006，22，6： | 1 |
| 16 | Do vanadate polyanions inhibit phosphotransferase enzymes显示文摘 | Donald W B Kenneth K Maho N | | 0，，： | 1 |
| 17 | Structures of four new alkaloids from Stemona sessilifolia显示文摘 | Yukio Hitotsuyanagi Maho I-Iikita Takahisa Oda | 2007 | Tetrahedron2007，63，4： | 1 |
| 18 | Effects of red ginseng extract on UVB irradiation induced skin aging in hairless mice显示文摘 | Young G K Maho S Masahiro S | 2009 | European Journal of Pharmacology2009，602，1： | 1 |
| 19 | A new Spanish family with CADASIL associated with 346C > T mutation of NOTCH3 gene 显示文摘 | Avila A Bello J Maho P | 2007 | Neurologia2007，22，7： | 1 |
| 20 | In vitro accumulation of tetrodotoxin in puffer fish liver tissue slices 显示文摘 | Yuji N Maho T Masahide H | 2003 | Toxicon2003，41，： | 1 |
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