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| 1 | Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review显示文摘AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical therapy.METHODS:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,2013.Treatment effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat basis.RESULTS:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was observed.In IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved remission.One RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were rare.CONCLUSION:FMT is highly effective in CDI,and holds promise in UC.As for CD,chronic constipation,pouchitis and IBS data are too limited to draw conclusions.FMT increases insulin sensitivity in metabolic syndrome. | Noortje G Rossen John K Mac Donald Elisabeth M de Vries Geert R D'Haens Willem M de Vos Erwin G Zoetendal Cyriel Y Ponsioen | 2015 | World Journal of Gastroenterology2015，21，17： | 41 |
| 2 | ' Green tides' are overwhelming the coastline of our blue planet: taking the world's largest example 显示文摘 | Ye bl H Zhang X W Mac Y Z | 2011 | Ecological Research2011，26，3： | 1 |
| 3 | Concerning the significance of paraoxonase-1 and SR-B1 genes in atherosclerosis显示文摘 | Rodríguez Esparragón F Hernández Trujillo Y Macías Reyes A | 2006 | Rev Esp Cardiol2006，59，2： | 1 |
| 4 | Amygdala and hippocampal volumes in familial early onset major depressive dis- order显示文摘 | MAC MASTER EP MIRZA Y SZESKO PR | 2008 | Biol Psychiatry2008，63，4： | 1 |
| 5 | Global transcriptome profiles of Camellia sinensis during cold acclimation 显示文摘 | WANG X C ZHAO Q Y MAC L | 2013 | BMC Genomics2013，14，： | 1 |
| 6 | A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotoein/ nicotinamide-induced type Clinical Biochemistry and 2 diabetes 显示文摘 | CHOU T W MAC Y CHENG H H | 2009 | Journal of Nutrition2009，45，1： | 1 |
| 7 | Preparative separation and purifica- tion of rosavin in Rhodiola rosea by macroporous adsorption resins 显示文摘 | MAC Y TAO G J TANG J | 2009 | Sep Purif Technol2009，69，1： | 1 |
| 8 | The Texas Children’s Hos-pital Pediatric Advanced Warning Score as a Predictor ofClinical Deterioration in Hospitalized Infants and Children:A Modification of the PEWS Tool显示文摘 | Bell D Mac A Ochoa Y | 2013 | J Pediatr Nurs2013，28，6： | 1 |
| 9 | Study of thermal properties andheat-induced denaturation and aggregation of soy proteins by modulated differential scanning calorimetry显示文摘 | TANG Chuanhe CHOI S M MAC Y | 2007 | International Journal of Biological Macromolecules2007，40，： | 1 |
| 10 | Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells显示文摘 | De Paepe ME Mac Q Chao Y | 2005 | Am J Physiol Lung Cell Mol Physiol2005，289，4： | 1 |
| 11 | MIMO radar 3D imaging based on combined amplitude and total variation cost function with sequential order one negative exponential form显示文摘 | MAC Z YEO T S ZHAO Y B | 2014 | IEEE Transactions on Image Processing2014，23，5： | 1 |
| 12 | The influence of magnesium on carbide characteristics and creep behavior of the MAR-M247 superalloy显示文摘 | BOR H Y CHAO C G MAC Y | 1998 | Scripta Materialia1998，38，2： | 1 |
| 13 | Characterization of globulin from Phaseolus angularis(red bean)显示文摘 | MENG Guantao MAC Y | 2002 | International Journal of Food Science and Technology2002，37，6： | 1 |
| 14 | Product quality control in semibatch reactors using midcourse correction policies 显示文摘 | YABUKI Y MAC GREGOR J | 1997 | Industrial and Engineering Chemistry Research1997，36，11： | 1 |
| 15 | Isolation and characterization of proteins from soymilk residue (okara)显示文摘 | MAC Y LIU W S KWOK K C | 1997 | Food Research International1997，29，8： | 1 |
| 16 | Study of thermal aggregation of globulin from common buckwheat (Fagopyrum esculentum Moench) by size- exclusion chromatography and laser light scattering显示文摘 | CHOI S M MAC Y | 2006 | Jourmal of Agricultural and Food Chemistry2006，54，1： | 1 |
| 17 | Ultrafine (nanometer) particle mediated lung injury显示文摘 | Donaldson K Li X Y Mac N W | 1998 | J Aerosol Sci1998，29，： | 1 |
| 18 | Thermal analysis of food proteins显示文摘 | MAC Y HARWALLKAR V R | 1991 | Adv Food Nutr Res1991，35，： | 1 |
| 19 | Tests of the Three-path Mediated Effect显示文摘 | Taylor A B Mac Kinnon D P&Tein J Y | 2008 | Organizational Research Methods2008，11，2： | 1 |
| 20 | Decomposition of nitrous oxide over Co-zeolite catalysts:Role of zeolite structure and active site显示文摘 | ZHANG X Y SHEN Q HE C MAC Y CHENG J LIU Z M HAO Z P | 2012 | Catal Sci Technol2012，2，6： | 1 |
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