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| 1 | De novo characterization of the root transcriptome of a traditional Chinese medicinal plant Polygonum cuspidatum显示文摘Various active components have been extracted from the root of Polygonum cuspidatum.However,the genetic basis for their activity is virtually unknown.In this study,25600002 short reads (2.3 Gb) of P.cuspidatum root transcriptome were obtained via Illumina HiSeq 2000 sequencing.A total of 86418 unigenes were assembled de novo and annotated.Twelve,18,60 and 54 unigenes were respectively mapped to the mevalonic acid (MVA),methyl-D-erythritol 4-phosphate (MEP),shikimate and resveratrol biosynthesis pathways,suggesting that they are involved in the biosynthesis of pharmaceutically important anthraquinone and resveratrol.Eighteen potential UDP-glycosyltransferase unigenes were identified as the candidates most likely to be involved in the biosynthesis of glycosides of secondary metabolites.Identification of relevant genes could be important in eventually increasing the yields of the medicinally useful constituents of the P.cuspidatum root.From the previously published transcriptome data of 19 non-model plant taxa,1127 shared orthologs were identified and characterized.This information will be very useful for future functional,phylogenetic and evolutionary studies of these plants. | HAO DaCheng MA Pei MU Jun CHEN ShiLin XIAO PeiGen PENG Yong HUO Li XU LiJia SUN Chao | 2012 | Science China(Life Sciences)2012，55，5： | 36 |
| 2 | Sexual and reproductive health service needs of university/ college students: updates from a survey in Shanghai, China显示文摘瞄准:由在上海探索大学学生的态度和感觉支持为年轻人的繁殖健康服务的预备,中国,向繁殖健康。方法:从 2004 年 7 月到 2006 年 5 月,在上海的 14 所大学的 5 243 个学生参加了我们的调查。话题在性健康上并且性用性,到色情材料的暴露,和知识盖住繁殖保健服务,对的态度和经验的要求播送感染(STI )/AIDS。结果:提供了有效答案表的 5 067 个学生, 50.05% 是女性, 49.95% 是男性的, 14.86% 是医学院的学生,并且 85.14% 有非医学的背景。38.4% 回答者的一个总数以前收到了繁殖卫生教育。学生的多数支持了基于学校的繁殖卫生教育,并且也从书,同学,和因特网主要关于性获得了信息。婚前的性行为被 17.7% 调查参加者反对,并且 37.5% 能识别在问询表列出的 STI 的所有三种类型。尽管 83.7% 知道了 HIV 怎么被播送,仅仅, 55.7% 知道了什么时候使用避孕套, 57.8% 知道避孕套的使用能减少 HIV 感染的风险。结论:繁殖健康服务正在落后于大学学生的当前的态度和要求。尽管学生对性事的态度是开明的,他们繁殖健康和 STIs/AIDS 的知识仍然是有限的。提供有效、机密的繁殖健康服务给年轻人因此是必要的。 | Bin Chen Yong-Ning Lu Hong-Xiang Wang Qing-Liang Ma Xiao-Ming Zhao Jian-Hua Guo Kai Hu Yi-Xin Wang Yi-Ran Huang Pei Chen | 2008 | Asian Journal of Andrology2008，10，4： | 20 |
| 3 | Risk factors for acute kidney injury in patients with acute myocardial infarction显示文摘Background:Acute kidney injury (AKI) is a serious and fatal complication of acute myocardial infarction (AMI).It has high shortand long-term mortality rates and a poor prognosis but is potentially preventable.However,the current incidence,risk factors,and outcomes of AKI in the Chinese population are not well understood and would serve the first step to identify high-risk patients who could receive preventative care.Methods:The medical data of 1124 hospitalized patients diagnosed with AMI from October 2013 to September 2015 were reviewed.AKI was defined according to the 2012 Kidney Disease Improving Global Outcomes criteria.All the patients were divided into either the AKI group or the non-AKI group.A univariate comparison analysis was performed to identify possible risk factors associated with AKI.A multiple logistic regression analysis was used to identify the independent risk factors for AKI in patients with AMI.Results:Overall,the incidence of AKI was 26.0%.The mortality rate of the AKI group was 20.5 %,and the mortality rate of the nonAKI group was 0.6%(P < 0.001).Logistic regression analysis showed that the independent risk factors for AKI in patients with AMI included:age (>60 years old)(odds ratio [OR] 1.04,95% confidence interval [CI] 1.02-1.05,P =0.000),hypertension (OR 2.51,95% CI 1.62-3.87,P =0.000),chronic kidney disease (OR 3.52,95% CI 2.01-6.16,P =0.000),Killip class ≥3 (OR 5.22,95% CI 3.07-8.87,P =0.000),extensive anterior myocardial infarction (OR 3.02,95% CI 1.85--4.93,P =0.000),use of furosemide (OR 1.02,95% CI 1.02-1.03,P =0.000),non-use of angiotensin-converting enzyme inhibitors/angiotensin receptor blocker (OR 1.58,95% CI 1.04-2.40,P =0.032).These factors provided an accurate tool to identify patients at high risk of developing AKI.Contusions:Approximately 26.0% of patients undergoing AMI developed AKI,and the development of AKI was strongly correlated with in-hospital mortality.The risk factors for AKI in patients with AMI were determined to help identify high-risk patients and make appropriate clinical decisions. | Cong Wang Yuan-Yuan Pei Yun-Hui Ma Xiao-Lu Ma Zhi-Wei Liu Ji-Hong Zhu Chun-Sheng Li | 2019 | Chinese Medical Journal2019，，14： | 20 |
| 4 | Curcumin inhibits hepatitis B virus infection by downregulating ccc DNA-bound histone acetylation显示文摘AIM To investigate the potential effect of curcumin on hepatitis B virus(HBV) covalently closed circular DNA(ccc DNA) and the underlying mechanism.METHODS A Hep G2.2.15 cell line stably transfected with HBV was treated with curcumin, and HBV surface antigen(HBs Ag) and e antigen(HBe Ag) expression levels were assessed by ELISA. Intracellular HBV DNA replication intermediates and ccc DNA were detected by Southern blot and real-time PCR, respectively. The acetylation levels of histones H3 and H4 were measured by Western blot. H3/H4-bound ccc DNA was detected by chromatin immunoprecipitation(Ch IP) assays. The deacetylase inhibitors trichostatin A and sodium butyrate were used to study the mechanism of action for curcumin. Additionally, short interfering RNAs(si RNAs) targeting HBV were tested along with curcumin.RESULTS Curcumin treatment led to time-and dose-dependent reductions in HBs Ag and HBe Ag expression and significant reductions in intracellular HBV DNA replication intermediates and HBV ccc DNA. After treatment with 20 μmol/L curcumin for 2 d, HBs Ag and ccc DNA levels in Hep G2.2.15 cells were reduced by up to 57.7%(P < 0.01) and 75.5%(P < 0.01), respectively, compared with levels in non-treated cells. Meanwhile, time-and dose-dependent reductions in the histone H3 acetylation levels were also detected upon treatment with curcumin, accompanied by reductions in H3-and H4-bound ccc DNA. Furthermore, the deacetylase inhibitors trichostatin A and sodium butyrate could block the effects of curcumin. Additionally, transfection of si RNAs targeting HBV enhanced the inhibitory effects of curcumin.CONCLUSION Curcumin inhibits HBV gene replication via downregulation of ccc DNA-bound histone acetylation and has the potential to be developed as a ccc DNA-targeting antiviral agent for hepatitis B. | Zhi-Qiang Wei Yong-Hong Zhang Chang-Zheng Ke Hong-Xia Chen Pan Ren Yu-Lin He Pei Hu De-Qiang Ma Jie Luo Zhong-Ji Meng | 2017 | World Journal of Gastroenterology2017，23，34： | 18 |
| 5 | Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson’s disease by regulating gut microbiota显示文摘The phenylalanine-tyrosine-dopa-dopamine pathway provides dopamine to the brain.Iin this process,tyrosine hydroxylase(TH)isthe rate-limiting enzyme that hydroxylates tyrosine and generates levodopa(L-dopa)with tetranydrobiopterin(BH_(4))as a coenzyme.Here,we show that oral berberine(BBR)might supply H^(·) through dihydroberberine(reduced BBR produced by bacterial nitroreductase)and promote the production of BHl from dihydrobiopterin;the increased BH,enhances TH activity,which accelerates the production of L-dopa by the gut bacteria.Oral BBR acts in a way similar to vitamins.The L-dopa produced by theintestinal bacteria enters the brain through the circulation and is transformed to dopamine.To verify the gut-brain dialog activatedby BBR's effect,Enterococcus foecalis or Enterococcus faecium was transplanted into Parkinson's disease(PD)mice.The bacteriasignificantly increased brain dopamine and ameliorated PD manifestation in mice;additionally,combination of BBR with bacteriashowed better therapeutic effect than that with bacteria alone.Moreover,2,4,6-trimethy-pyranylium tetrafluoroborate(TMP-TFB)-derivatized matrix-assisted laser desorption mass spectrometry(MALDI-MS)imaging of dopamine identihed elevated striataldopamine levels in mouse brains with oral Enterococcus,and BBR strengthened the imaging intensity of brain dopamine.Theseresults demonstrated that BBR was an agonist of TH in Enterococcus and could lead to the production of L-dopa in the gut.Furthermore,a study of 28 patients with hyperlipidemia conhrmed that oral BBR increased bloodfecal L-dopa by the intestinalbacteria.Hence,BBR might improve the brain function by upregulating the biosynthesis of-dopa in the gut microbiota through avitamin-like effect. | Yan Wang Qian Tong Shu-Rong Ma Zhen-Xiong Zhao Li-Bin Pan Lin Cong Pei Han Ran Peng Hang Yu Yuan Lin Tian-Le Gao Jia-Wen Shou Xiao-Yang Li Xian-Feng Zhang Zheng-Wei Zhang Jie Fu Bao-Ying Wen Jin-Bo Yu Xuetao Cao Jian-Dong Jiang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 16 |
| 6 | Electroacupuncture preconditioning protects against focal cerebral ischemia/reperfusion injury via suppression of dynamin-related protein 1显示文摘Electroacupuncture preconditioning at acupoint Baihui(GV20) can reduce focal cerebral ischemia/reperfusion injury. However, the precise protective mechanism remains unknown. Mitochondrial fission mediated by dynamin-related protein 1(Drp1) can trigger neuronal apoptosis following cerebral ischemia/reperfusion injury. Herein, we examined the hypothesis that electroacupuncture pretreatment can regulate Drp1, and thus inhibit mitochondrial fission to provide cerebral protection. Rat models of focal cerebral ischemia/reperfusion injury were established by middle cerebral artery occlusion at 24 hours after 5 consecutive days of preconditioning with electroacupuncture at GV20(depth 2 mm, intensity 1 m A, frequency 2/15 Hz, for 30 minutes, once a day). Neurological function was assessed using the Longa neurological deficit score. Pathological changes in the ischemic penumbra on the injury side were assessed by hematoxylin-eosin staining. Cellular apoptosis in the ischemic penumbra on the injury side was assessed by terminal deoxyribonucleotidyl transferase-mediated d UTP-digoxigenin nick end labeling staining. Mitochondrial ultrastructure in the ischemic penumbra on the injury side was assessed by transmission electron microscopy. Drp1 and cytochrome c expression in the ischemic penumbra on the injury side were assessed by western blot assay. Results showed that electroacupuncture preconditioning decreased expression of total and mitochondrial Drp1, decreased expression of total and cytosolic cytochrome c, maintained mitochondrial morphology and reduced the proportion of apoptotic cells in the ischemic penumbra on the injury side, with associated improvements in neurological function. These data suggest that electroacupuncture preconditioning-induced neuronal protection involves inhibition of the expression and translocation of Drp1. | Gao-feng Zhang Pei Yang Zeng Yin Huai-long Chen Fu-guo Ma Bin Wang Li-xin Sun Yan-lin Bi Fei Shi Ming-shan Wang | 2018 | Neural Regeneration Research2018，13，1： | 16 |
| 7 | Seasonal and diurnal variations in N2O concentrations and fluxes from three eutrophic rivers in Southeast China显示文摘这研究在试图决定溶解 N2O 集中和流动的大小和模式在上的东南中国在三条发育营养正常促进剂河被执行一季节(在 2009 ) 并且日报(24 h ) 时间的规模。结果显示出集中从 0.28 ~ 0.38 改变了的那 N2O (平均数 0.32 獡獩漠 ? 湵散瑲楡瑮 ? 潳牵散吗? | YANG Libiao YAN Weijin MA Pei WANG Jianing | 2011 | Journal of Geographical Sciences2011，21，5： | 15 |
| 8 | A GPCR/secretase complex regulates β- and γ-secretase specificity for Aβ production and contributes to AD pathogenesis显示文摘尾 - 地点的 Dysregulation 劈开应用软件的酶(BACE ) 或纬 - secretase 导致异常生产淀粉 -- 尾肽(尾) 并且贡献 Alzheimer 的疾病(广告) 的病原学。自从这些 secretases,调停众多的蛋白质的解朊的处理,因为不可避免的不希望得到的副作用,小成功都没被获得由 secretase 禁止者对待广告。因此,解开具有重要性这些 secretases 的规章的机制。这里,我们证明那未 - opioid 受体(欧洲粪金龟子) 支持由 BACE1 和纬 - 处理尾先锋蛋白质(应用软件) secretase,然而并非槽口, N-cadherin 或 APLP 的。进一步的调查表明那只欧洲粪金龟子与 BACE1 和纬 - secretase 形成建筑群,并且欧洲粪金龟子的激活调停为应用软件 endoproteolysis secretases/receptor 建筑群排序的 co-endocytic。受体的机能障碍延迟 BACE1 和纬 - secretase 并且这样的 endocytosis 尾的生产。一致地,击倒或欧洲粪金龟子的 antagonization 减少 secretase 活动并且改善一个尾病理和 A 尾 - 依赖者行为的赤字,但是不影响在广告模型老鼠处理槽口, N-cadherin 或 APLP。我们的学习不仅揭开为为尾生产调整 secretase 的特性而且建议形成的那干预或 GPCR/secretase 建筑群的 trafficking 的 DOR/secretase 建筑群的形成的分子的机制能对广告导致新策略,潜在地与更少副作用。 | Lin Teng Jian Zhao Feifei Wang Lan Ma Gang Pei | 2010 | Cell Research2010，20，2： | 14 |
| 9 | Melting Characteristics of Iron Ore Fine During Sintering Process显示文摘The whole melting curve of iron ore during sintering process was obtained,and the melting characteristics of iron ore were defined and explained. The whole melting process of mixture,mixed by iron ore and CaO reagent at basicity of 2.0 and 4.0,respectively,was observed using a SiC heating furnace with camcorder unit,and the melting curves of mixture that were relative height vs temperature curves were obtained. Besides,the melting characteristics of iron ore during sintering were introduced through defining some points in the melting curves,such as liquid forming temperature,inflexion temperature and flowing temperature,and the meaning of different shapes of the melting curves was clarified. | LI Hong-ge ZHANG Jian-liang PEI Yuan-dong ZHAO Zhi-xing MA Ze-jun | 2011 | Journal of Iron and Steel Research(International)2011，18，5： | 14 |
| 10 | The Qitai radio telescope显示文摘This study presents a general outline of the Qitai radio telescope(QTT)project.Qitai,the site of the telescope,is a county of Xinjiang Uygur Autonomous Region of China,located in the east Tianshan Mountains at an elevation of about 1800 m.The QTT is a fully steerable,Gregorian-type telescope with a standard parabolic main reflector of 110 m diameter.The QTT has adopted an umbrella support,homology-symmetric lightweight design.The main reflector is active so that the deformation caused by gravity can be corrected.The structural design aims to ultimately allow high-sensitivity observations from 150 MHz up to115 GHz.To satisfy the requirements for early scientific goals,the QTTwill be equipped with ultra-wideband receivers and large field-of-view multi-beam receivers.A multi-function signal-processing system based on RFSo C and GPU processor chips will be developed.These will enable the QTT to operate in pulsar,spectral line,continuum and Very Long Baseline Interferometer(VLBI)observing modes.Electromagnetic compatibility(EMC)and radio frequency interference(RFI)control techniques are adopted throughout the system design.The QTT will form a world-class observational platform for the detection of lowfrequency(nano Hertz)gravitational waves through pulsar timing array(PTA)techniques,pulsar surveys,the discovery of binary black-hole systems,and exploring dark matter and the origin of life in the universe.The QTT will also play an important role in improving the Chinese and international VLBI networks,allowing high-sensitivity and high-resolution observations of the nuclei of distant galaxies and gravitational lensing systems.Deep astrometric observations will also contribute to improving the accuracy of the celestial reference frame.Potentially,the QTT will be able to support future space activities such as planetary exploration in the solar system and to contribute to the search for extraterrestrial intelligence. | Na Wang Qian Xu Jun Ma Zhiyong Liu Qi Liu Hailong Zhang Xin Pei Maozheng Chen Richard N.Manchester Kejia Lee Xingwu Zheng Hans J.Kärcher Wulin Zhao Hongwei Li Dongwei Li Martin Süss Matthias Reichert Zhongyi Zhu Congsi Wang Mingshuai Li Rui Li Ning Li Guljaina Kazezkhan Wenming Yan Gang Wu Lang Cui Ming Zhang Haitao Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 14 |
| 11 | COVID-19: Challenges to GIS with Big Data显示文摘The outbreak of the 2019 novel coronavirus disease(COVID-19)has caused more than 100,000 people infected and thousands of deaths.Currently,the number of infections and deaths is still increasing rapidly.COVID-19 seriously threatens human health,production,life,social functioning and international relations.In the fight against COVID-19,Geographic Information Systems(GIS)and big data technologies have played an important role in many aspects,including the rapid aggregation of multi-source big data,rapid visualization of epidemic information,spatial tracking of confirmed cases,prediction of regional transmission,spatial segmentation of the epidemic risk and prevention level,balancing and management of the supply and demand of material resources,and socialemotional guidance and panic elimination,which provided solid spatial information support for decision-making,measures formulation,and effectiveness assessment of COVID-19 prevention and control.GIS has developed and matured relatively quickly and has a complete technological route for data preparation,platform construction,model construction,and map production.However,for the struggle against the widespread epidemic,the main challenge is finding strategies to adjust traditional technical methods and improve speed and accuracy of information provision for social management.At the data level,in the era of big data,data no longer come mainly from the government but are gathered from more diverse enterprises.As a result,the use of GIS faces difficulties in data acquisition and the integration of heterogeneous data,which requires governments,businesses,and academic institutions to jointly promote the formulation of relevant policies.At the technical level,spatial analysis methods for big data are in the ascendancy.Currently and for a long time in the future,the development of GIS should be strengthened to form a data-driven system for rapid knowledge acquisition,which signifies ts that GIS should be used to reinforce the social operation parameterization of models and methods,especially when providing support for social management. | Chenghu Zhou Fenzhen Su Tao Pei An Zhang Yunyan Du Bin Luo Zhidong Cao Juanle Wang Wen Yuan Yunqiang Zhu Ci Song Jie Chen Jun Xu Fujia Li Ting Ma Lili Jiang Fengqin Yan Jiawei Yi Yunfeng Hu Yilan Liao Han Xiao | 2020 | Geography and Sustainability2020，1，1： | 13 |
| 12 | W55a Encodes a Novel Protein Kinase That Is Involved in Multiple Stress Responses显示文摘Protein kinases play crucial roles in response to external environment stress signals.A putative protein kinase,W55a,belonging to SNF1-related protein kinase 2(SnRK2) subfamily,was isolated from a cDNA library of drought-treated wheat seedlings.The entire length of W55a was obtained using rapid amplification of 5 cDNA ends(5 -RACE) and reverse transcription-polymerase chain reaction(RT-PCR).It contains a 1029-bp open reading frame(ORF) encoding 342 amino acids.The deduced amino acid sequence of W55a had eleven conserved catalytic subdomains and one Ser/Thr protein kinase active-site that characterize Ser/Thr protein kinases.Phylogenetic analysis showed that W55a was 90.38% homologous with rice SAPK1,a member of the SnRK2 family.Using nullisomic-tetrasomic and ditelocentric lines of Chinese Spring,W55a was located on chromosome 2BS.Expression pattern analysis revealed that W55a was upregulated by drought and salt,exogenous abscisic acid,salicylic acid,ethylene and methyl jasmonate,but was not responsive to cold stress.In addition,W55a transcripts were abundant in leaves,but not in roots or stems,under environmental stresses.Transgenic Arabidopsis plants overexpressing W55a exhibited higher tolerance to drought.Based on these findings,W55a encodes a novel dehydration-responsive protein kinase that is involved in multiple stress signal transductions. | Zhao-Shi Xu Li Liu Zhi-Yong Ni Pei Liu Ming Chen Lian-Cheng Li Yao-Feng Chen You-Zhi Ma | 2009 | Journal of Integrative Plant Biology2009，51，1： | 13 |
| 13 | A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes显示文摘Thermal runaway has been a long-standing safety issue impeding the development of high-energydensity batteries. Physical safety designs such as employing circuit-breakers and fuses to batteries are limited by small operating voltage windows and no resumption of original working condition when it is cooled down. Here we report a smart thermoresponsive polymer electrolyte that can be incorporated inside batteries to prevent thermal runaway via a fast and reversible sol-gel transition, and successfully combine this smart electrolyte with a rechargeable Zn/a-MnO_2 battery system. At high temperature, battery operation is inhibited as a result of the increased internal resistance caused by the gelation of liquid electrolyte. After cooling down, the electrolyte is spontaneously reversed to sol state and the electrochemical performance of the battery is restored. More importantly, sol-gel transition enables the smart battery to experience different charge-discharge rates under various temperature levels, providing a smart and active strategy to achieve dynamic and reversible self-protection. | Funian Mo Hongfei Li Zengxia Pei Guojin Liang Longtao Ma Qi Yang Donghong Wang Yan Huang Chunyi Zhi | 2018 | Science Bulletin2018，63，16： | 13 |
| 14 | A review on China's constructed wetlands in recent three decades:Application and practice显示文摘Constructed wetlands(CWs)have been introduced to and developed in China for environmental engineering over the most prosperous three decades(1990–2020).To study the origin,development process,and future trend of CWs,this review summarized a wide range of literatures between 1990 and 2020 by Chinese authors.Firstly,the publication number over years,research highlights,and the author contributions with the most published papers in this field were conducted through bibliometric analysis.Secondly,the most principal components of CWs,substrates and macrophytes were summarized and analyzed.Thirdly,the typical application cases from traditional CWs,pond systems to combined pond-wetland systems were presented.In China,CWs were predominately distributed in the east of the so-called'Hu Huanyong Line'.Therefore CWs were limited by the socio-economic level and climatic conditions.It is unquestionable that the overall level of China's CWs has improved significantly,and one of the most prominent features has started towards the plural pattern development.There has been a trend of large-scale or low-cost CW application in the recent years.However,lifecycle research and management are required for better strategies in the future. | Hong Zhang Wenzhong Tang Weidong Wang Wei Yin Honglei Liu Xiaomin Ma Yiqi Zhou Pei Lei Dongyang Wei Litian Zhang Cao Liu Jinmiao Zha | 2021 | Journal of Environmental Sciences2021，33，6： | 13 |
| 15 | Graphene-supported nanoscale zero-valent iron:Removal of phosphorus from aqueous solution and mechanistic study显示文摘Excess phosphorus from non-point pollution sources is one of the key factors causing eutrophication in many lakes in China,so finding a cost-effective method to remove phosphorus from non-point pollution sources is very important for the health of the aqueous environment. Graphene was selected to support nanoscale zero-valent iron(nZVI)for phosphorus removal from synthetic rainwater runoff in this article. Compared with nZVI supported on other porous materials,graphene-supported nZVI(G-nZVI) could remove phosphorus more efficiently. The amount of nZVI in G-nZVI was an important factor in the removal of phosphorus by G-nZVI,and G-nZVI with 20 wt.% nZVI(20% G-nZVI)could remove phosphorus most efficiently. The nZVI was very stable and could disperse very well on graphene,as characterized by transmission electron microscopy(TEM) and scanning electron microscopy(SEM). X-ray photoelectron spectroscopy(XPS),Fourier Transform infrared spectroscopy(FT-IR) and Raman spectroscopy were used to elucidate the reaction process,and the results indicated that Fe-O-P was formed after phosphorus was adsorbed by G-nZVI. The results obtained from X-ray diffraction(XRD) indicated that the reaction product between nZVI supported on graphene and phosphorus was Fe3(PO4)2·8H2O(Vivianite). It was confirmed that the specific reaction mechanism for the removal of phosphorus with nZVI or G-nZVI was mainly due to chemical reaction between nZVI and phosphorus. | Fenglin Liu JingHe Yang Jiane Zuo Ding Ma Lili Gan Bangmi Xie Pei Wang Bo Yang | 2014 | Journal of Environmental Sciences2014，26，8： | 12 |
| 16 | CH_4 Concentrations and Emissions from Three Rivers in the Chaohu Lake Watershed in Southeast China显示文摘This study was conducted at three rivers of the Chaohu Lake watershed during the summer season of 2008,aiming to investigate the diurnal variations of dissolved CH4 concentrations and emissions,as well as the dynamics of CH4 accumulation emission rates over consecutive 72 h.The results showed that CH4 concentrations in the Fengle,Hangbu,and Nanfei rivers ranged from 56.33-124.79,160.82-341.03,and 213.49-716.81 nmol L-1,respectively,over a daily cycle;while the saturation of CH4 ranged from 188.72-418.07,538.74-1 142.46,and 715.23-2 401.38%,respectively,which indicated that surface waters were in all cases oversaturated with respect to the atmosphere.An obvious diurnal variation pattern of the dissolved CH4 concentrations demonstrated a higher value during daytime but a lower value for night time.Additionally,the highest dissolved CH4 concentrations were detected in the Nanfei River which received substantial urban wastewater discharges.CH4 emissions measured with floating chambers ranged from 5.82-15.46,5.77-8.41,and 13.51-49.25 mg C m-2 h-1 for the Fengle,Hangbu,and Nanfei rivers,respectively,over a daily cycle.Significantly higher CH4 emissions were also observed from the Nanfei River.The accumulative CH4 emissions for each river increased with time,while a decline trend on the accumulation rates was investigated over the consecutive 72 h. | YANG Li-biao LI Xin-yan YAN Wei-jin MA Pei WANG Jia-ning | 2012 | Journal of Integrative Agriculture2012，11，4： | 11 |
| 17 | Bedaquiline-containing regimens in patients with pulmonary multidrug-resistant tuberculosis in China:focus on the safety显示文摘Background:World Health Organization recommends countries introducing new drug and short treatment regimen for drug resistant tuberculosis(DR-TB)should develop and implement a system for active pharmacovigilance that allows for detection,reporting and management of adverse events.The aim of the study is to evaluate the frequency and severity of adverse events(AEs)of bedaquiline-containing regimen in a cohort of Chinese patients with multidrug-resistant(MDR)/extensively drug-resistant(XDR)-TB based on active drug safety monitoring(aDSM)system of New Drug Introduction and Protection Program(NDIP). | Jing-Tao Gao Juan Du Gui-Hui Wu Yi Pei Meng-Qiu Gao Leonardo Martinez Lin Fan Wei Chen Li Xie Yu Chen Hua Wang Long Jin Guo-Bao Li Pei-Lan Zong Yu Xiong Qian-Hong Wu Ming-Wu Li Xiao-Feng Yan Yan-Fang Miao Qing-Shan Cai Xin-Jie Li Da-Peng Bai Shu-Jun Geng Guo-Li Yang Pei-JunTang Yi Zeng Xiao-Hong Chen Tong-Xia Li Cui Cai Yun Zhou Ma Zhuo Jian-Yun Wang Wen-Long Guan Lin Xu Ji-Chan Shi Wei Shu Li-Li Cheng FeiTeng Yu-Jia Ning Shi-Heng Xie Yu-Xian Sun Li-Jie Zhang Yu-Hong Liu | 2021 | Infectious Diseases of Poverty2021，10，2： | 11 |
| 18 | Differentiation potential of bone marrow mesenchymal stem cells into retina in normal and laser-injured rat eye显示文摘Bone marrow mesenchymal stem cells (MSCs) can develop into hematopoietic and mesenchymal lineages but have not been known to participate in the production of retina. Here we report that bone marrow mesenchymal stem cells, after being subretinally transplanted into normal or Nd: YAG laser-injured rat eye, can integrate into RPE layer, photoreceptor layer, bi-polar cell layer and ganglion layer. DAPI-labeling detection was used to trace the origin of the repopulating cells. DAPI fluorescence was used to identify retina cells of bone marrow origin 10, 20, 35 and 50 days after transplantation. No formation of rosettes was found but some random cells were found at the end of the observation. MSCs-originated cells spread more widely in the injured retinas than in the normal ones. Immunohistochemical detection showed that though the cells could express neuronal nuclei (NeuN), neuron specific enolase (NSE), glial fibrillary acidic protein (GFAP) and cytokeratin (CK), the proteins expression in the injured transplantation group was abnormal in some region compared with that in the normal transplantation group. Elec-troretinogram (ERG) showed that ERG-b wave of the injured transplantation group is significantly higher than that of the two laser-injured control groups. These results suggest that a proportion of MSCs can differentiate into retina-like structure in vivo and the differentiation differs in normal and laser-injured retinas. | ZHANG Jie1,2, SHAN Qing1, MA Ping1, JIANG Yanming1, CHEN Peng1, WEN Jingxia1, ZHOU You1, QIAN Huanwen1 & PEI Xuetao2 1. Beijing Institute of Radiation Medicine, Beijing 100850, China 2. Beijing Institute of Transfusion Medicine, Beijing 100850, China | 2004 | Science China(Life Sciences)2004，47，3： | 10 |
| 19 | A critical review on the health promoting effects of mushrooms nutraceuticals显示文摘Extensive elucidations focusing on the efficient health promoting properties and high nutritional values of mushrooms have been expanded dynamically from the past few decades.Due to its high quality of proteins,polysaccharides,unsaturated fatty acids,mineral substances,triterpenes sterols and secondary metabolites,mushrooms have always been appreciated for their vital role in protecting and curing various health problems,such as immunodeficiency,cancer,inflammation,hypertension,hyperlipidemia,hypercholesterolemia and obesity.Moreover,investigations in recent years have revealed the correlations between the health-promoting benefits and gut microbiota regulating effects induced by the mushrooms intake.Researches on the immense role in the nutritional and health benefits displayed by mushrooms have become an emergent task to study.The present article overviewed and compiled the latest information correlated to the health benefits and underlying functional mechanisms of mushroom nutraceuticals,and concluded that the supplementation of mushrooms as a dietary composition could become a natural adjuvant for the prevention and treatment of several health diseases. | Gaoxing Ma Wenjian Yang Liyan Zhao Fei Pei Donglu Fang Qiuhui Hu | 2018 | Food Science and Human Wellness2018，7，2： | 10 |
| 20 | Comparison of phylobetadiversity indices based on community data from Gutianshan forest plot显示文摘Phylobetadiversity incorporates phylogenetic information and beta diversity,and can account for the ecological similarities between communities with a phylogenetic perspective.Although different phylobetadiversity indices reflect differences in different characteristics between communities,the results of different phylobetadiversity indices are not comparable.In this study we examined phylobetadiversity indices for a 24-hm 2 plot in the Gutianshan National Nature Reserve.It was found the abundanceweighted D pw was almost identical to Rao's D of Rao's quadratic entropy.PhyloSor had a similar ecological meaning and algorithm to UniFrac.Although Dnn was different in definition from UniFrac and PhyloSor,they were all strongly correlated.The effect of species abundance on phylobetadiversity was not significant when scales were relatively small,but was significant at larger scales.These contrasts likely resulted from reductions in evenness in communities as scales increased.P ST and Rao's H better reflected the distance-decay changes caused by spatial and habitat variation than other indices at larger scales,whereas AW-D nn and D nn better reflected these changes at small scales. | FENG Gang ZHANG JinLong PEI NanCai RAO MiDe MI XiangCheng REN HaiBao MA KePing | 2012 | Chinese Science Bulletin2012，57，6： | 9 |
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