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| 1 | 世界胃肠病学组织全球指南——发展中国家幽门螺杆菌感染显示文摘世界上有一半人口感染幽门螺杆菌(H.pylori),其感染率因地理位置、种族、年龄和社会经济状况不同而存在很大差异.在发展中国家较高.发达国家较低。但总体而言,近年世界许多地区的H.pylori感染率均呈下降趋势。 | Hunt RH Xiao SD Megraud F Leon-Barua R Bazzoli F van der Merwe S Vaz Coelho LG Fock M Fedail S Cohen H Malfertheiner P Vakil N Hamid S Goh KL Wong BCY Krabshuis J Le Mair A 杜颖 戴宁 | 2011 | 胃肠病学2011,16,7: | 27 |
| 2 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009,15,9: | 6 |
| 3 | Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication显示文摘 | Hilde M van der Schaar Lonneke van der Linden Kjerstin H W Lanke Jeroen R P M Strating Gerhard Purstinger Erik de Vries Cornelis A M de Haan Johan Neyts Frank J M van Kuppeveld | 2012 | Cell Research2012,22,11: | 3 |
| 4 | Effects of conventional and problem‐based learning on clinical and general competencies and career development显示文摘 | JankeCohen‐Schotanus Arno M MMuijtjens JohannaSch?nrock‐Adema JelleGeertsma Cees P MVan Der Vleuten | 2008 | Medical Education2008,,3: | 2 |
| 5 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017,25,2: | 2 |
| 6 | Pulmonary hypertension after transjugular intrahepatic portosystemic shunt: Effects on right ventricular function显示文摘 | P Van der Linden O Le Moine M Ghysels M Ortinez J Deviere | 1996 | Hepatology1996,,5: | 2 |
| 7 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006,12,28: | 2 |
| 8 | A domain size effect in the magnetic hysteresis of NiZn-ferrites 显示文摘 | Van Der Zagg P J Van Der Valk P J Rekveldt M T | 1996 | Appl Phys Lett1996,69,19: | 1 |
| 9 | The use of biological activated carbon filtration for the removal of natural organic matter and organic micropollutants from water 显示文摘 | J P van der Hoek J A M H Hofman A Graveland | 1999 | Water Science and Technology1999,40,9: | 1 |
| 10 | The p rog-nostic significance of membrane transport2associated multidrug resistance (MDR) proteins in leukenia 显示文摘 | Van der Heuvel-EibrinkM M Sonneveld P Pieters R | 2000 | Int J Clin Pharmacol Ther2000,38,3: | 1 |
| 11 | Agricultural nutrient losses to surface water in the Netherlands:Impact, strategies, and perspectives显示文摘 | Van Der Molen D T Breeuwsma A Boers P C M | 1998 | Journal of Environmentol Quality1998,27,1: | 1 |
| 12 | The relation between morphology and hydrotreating activity for supported MoS2 particles 显示文摘 | HENSEN E J M KOOYMAN P J Van der MEER Y Van der KRAAN A M de BEER V H J Van VEEN J A R Van SANTEN R A | 2001 | J Catal2001,199,2: | 1 |
| 13 | Expression of the potato leafroll luteovirus coat protein gene in transgenic potato plant inhibits viral infection显示文摘 | WILLINK D P L HUISMAN M J | 1991 | Plant Molecular Biology1991,17,: | 1 |
| 14 | Catalytic growth of macroscopic carbon nanofiber bodies with high bulk density and high mechanical strength显示文摘 | Lee M K van der Dillen A J van Geus J W Jong K P de Bitter J H | 2006 | Carbon2006,44,: | 1 |
| 15 | PCR-based DNA test to confirm clinical diagnosis of autosomal recessive spinal muscular atrophy显示文摘 | Van der Steege G Grootscholten P M van der Vlies P | 1995 | Lancet1995,345,8995: | 1 |
| 16 | Verfication of workflow task structures: a petri-net-based approach 显示文摘 | AALST van der W M P HOFSTEDE ter A H M | 2000 | Information Systems2000,25,1: | 1 |
| 17 | Work- flow mining A survey of issues and approaehes显示文摘 | van der Aalst W M P van Dongen B F Herbst J | 2003 | Data and Know ledge Engineering2003,47,2: | 1 |
| 18 | A novel approach for process mining based on event types显示文摘 | WEN Lijie WANG Jianmin VAN DER AALST W M P | 2009 | Journal of Intellegent Information Systems2009,32,2: | 1 |
| 19 | The Application of Petri Nets to Workflow Management 显示文摘 | Van der Aalst W M P | 1998 | The Journal of Circuits Systems and Computers1998,8,1: | 1 |
| 20 | Quantifying process equivalence based on ob- served behavior 显示文摘 | ALVES DE MEDEIROS A K van der AALST W M P WEIJTERS A | 2008 | Data and Knowledge Engineering2008,64,1: | 1 |