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| 1 | Early palliative care for patients with metastatic non-small-cell lung cancer显示文摘Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnosis may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer(NSCLC).If validated,these findings could support a paradigm shift in the care of adults with metastatic NSCLC and possibly patients with other tumor types characterized by short survival and high symptom burden. | Temel JS Greer JA Muzikansky A Gallagher ER Admane S Jackson VA Dahlin CM Blinderman CD Jacobsen J Pirl WF Billings JA Lynch TJ | 2010 | 中国肺癌杂志2010，13，9： | 165 |
| 2 | Grinding process within vertical roller mills: experiment and simulation显示文摘Based on screening analysis, laser size analysis, grindability and rigidity tests of samples collected on line from a cement and a power plant, a simulation of the grinding process in vertical roller mills was carried out. The simulation calculation used a breakage function, B. The results indicate that the breakage function, B, and the selection function, S, in the form of a matrix, can be used to express the probability of the material breaking during the grinding process. This allows the size distribution of the product to be numerically estimated. The simulation results also show that the simulated size distribution curves fit the actual experimental product curves quite well. The model provides a good starting point for simulation of the grinding process. Further research is needed to determine the proper breakage function and the matrix value of the selection function. | WANG Jian-huai CHEN Qing-ru KUANG Ya-li LYNCH A j ZHUO Jin-wu | 2009 | Mining Science and Technology2009，19，1： | 11 |
| 3 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 4 | Beta-adrenergic-dependent and -independent actions of naloxone on perfusion during endotoxin shock显示文摘 | Dziki A J Lynch W H Ramsey C B | 1993 | Circ Shock1993，39，1： | 2 |
| 5 | Winter composting using the passively aerated windrow system显示文摘 | Lynch N J Cherry R S | 1996 | Compost Science & Utilization1996，4，3： | 2 |
| 6 | Interactions between biological processes, cultivation and soil structure显示文摘 | Lynch J M | 1984 | Plant Soil1984，76，： | 2 |
| 7 | A double-blind, placebocontrolled trial of sertraline for depressive symptoms in patients with stable,chronic schizophrenis 显示文摘 | Mulholland C Lynch G King D J | 2003 | J Psychopharmacol2003，17，： | 1 |
| 8 | Development of a regional climate model of the western Arctic 显示文摘 | Lynch A H Chapman W L Walsh J E | 1995 | Journal of Climate1995，8，： | 1 |
| 9 | A novel endothelial-derived lipase that modulatesHDL metabolism显示文摘 | Jaye M Lynch Kj Krawiec J | 1999 | Nat Genet1999，21，4： | 1 |
| 10 | The cracked tooth syndrome显示文摘 | Lynch C D McConnell R J | 2002 | J Can Dent Assoc2002，68，8： | 1 |
| 11 | Marked-based control of linear structural systems 显示文摘 | Lynch J P Law K H | 2002 | Earthquake Engineering and Structural Dynamics2002，31，10： | 1 |
| 12 | Studies on experimental hypertension:Production of persistent elevation of systolic blood pressure by means of renal ischemia显示文摘 | Goldblatt H Lynch J Hanzal R F Summerville W W | 1934 | J Exp Med1934，59，： | 1 |
| 13 | Lipoxygenase-generated hydroperoxides account for the nonphysiological features of ethylene formation from 1-aminocyclopropane-1-carboxylic acid by microsomal membranes of carnations显示文摘 | Lynch D V Sridhara S Thompson J E | 1995 | Planta1995，164，： | 1 |
| 14 | Hydride Formation Rates of Titanium-Based BCC Solid Solution Alloys显示文摘 | Maeland A J Libowitz G G Lynch J F | 1984 | J Less-Common Metals1984，104，： | 1 |
| 15 | Expression of a Bacillus thuringiensis cryIA (c)gene in transgenic peanut plants and its efficacy against lesser cornstalk borer显示文摘 | Singsit C Adang M J Lynch R E | 1997 | Transgenic Research1997，6，： | 1 |
| 16 | 显示文摘 | JEONG S SESSLER J L LYNCH V | 2008 | J Am Chem Soc2008，130，： | 1 |
| 17 | Oral antihistamines reduce the side effects from rapid vancomycin infusion显示文摘 | Renz CL Thurn JD Finn HA Lynch JP Moss J | 1998 | Anesth Analg1998，87，3： | 1 |
| 18 | Root architecture and plant productivity显示文摘 | Lynch J | 1995 | Plant Physiology1995，109，： | 1 |
| 19 | 查看详情显示文摘 | LYNCH B J ZHAO Y TRUHLAR D G | | 0，，： | 1 |
| 20 | 查看详情显示文摘 | D W Yoon D E Gross V M Lynch J M Sessler B P Hay C H Lee | | 0，，： | 1 |
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