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| 1 | Transgenerational Inheritance and Resetting of Stress, Induced Loss of Epigenetic Gene Silencing in Arabidopsis显示文摘作为无柄的有机体,植物需要察觉到并且适应异构的环境并且由改变他们的细胞的生理学,基因规定,和染色体稳定性开发了复杂回答。最近的工作在被建议具有 epigenetic 自然的 plantsa 现象在染色体稳定性的控制上表明了可继承的压力效果。这里,我们证明温度和 UV-B 应力在 Arabidopsis 在沉默记者基因的 epigenetic 控制引起立即、可继承的变化。基因 silencing 的这个调停压力的版本在 histone 占有并且在 histone H3 acetylation 与显著改变相关但是没在 DNA methylation 包含调整。我们在记者基因 silencing 上观察了压力效果的传播到非强调的子孙,但是这效果被限制为由房间的一个小数字组成的区域并且限制了到一些非强调的子孙代。而且,基因 silencing 的导致压力的版本在种子老化期间被反对并且重设。这现象的短暂性质加亮工厂的能力限制 epigenetic 控制机制的导致压力的松驰,它多半贡献保卫染色体完整。 | Christina Lang-Mladek Olga Popova Kathrin Kiok Marc Berlinger Branislava Rakic Werner Aufsatz Claudia Jonak Marie-Theres Hauser Christian Luschnig | 2010 | Molecular Plant2010，3，3： | 11 |
| 2 | TOLs Function as Ubiquitin Receptors in the Early Steps of the ESCRT Pathway in Higher Plants显示文摘Protein abundance and localization at the plasma membrane(PM)shapes plant development and mediates adaptation to changing environmental conditions.It is regulated by ubiquitination,a post-translational modification crucial for the proper sorting of endocytosed PM proteins to the vacuole for subsequent degradation.To understand the significance and the variety of roles played by this reversible modification,the function of ubiquitin receptors,which translate the ubiquitin signature into a cellular response,needs to be elucidated.In this study,we show that TOL(TOM1-like)proteins function in plants as multivalent ubiquitin receptors,governing ubiquitinated cargo delivery to the vacuole via the conserved Endosomal Sorting Complex Required for Transport(ESCRT)pathway.TOL2 and TOL6 interact with components of the ESCRT machinery and bind to K63-linked ubiquitin via two tandemly arranged conserved ubiquitin-binding domains.Mutation of these domains results not only in a loss of ubiquitin binding but also altered localization,abolishing TOL6 ubiquitin receptor activity.Function and localization of TOL6 is itself regulated by ubiquitination,whereby TOL6 ubiquitination potentially modulates degradation of PM-localized cargoes,assisting in the fine-tuning of the delicate interplay between protein recycling and downregulation.Taken together,our findings demonstrate the function and regulation of a ubiquitin receptor that mediates vacuolar degradation of PM proteins in higher plants. | Jeanette Moulinier-Anzola Maximilian Schwihla Lucinda De-Araujo Christina Artner Lisa Jorg Nataliia Konstantinova Christian Luschnig Barbara Korbei | 2020 | Molecular Plant2020，13，5： | 3 |
| 3 | Plasma Membrane Protein Ubiquitylation and Degradation as Determinants of Positional Growth in Plants显示文摘Being sessile organisms,plants evolved an unparalleled plasticity in their post‐embryonic development,allowing them to adapt and fne‐tune their vital parameters to an ever‐changing environment.Crosstalk between plants and their environment requires tight regulation of information exchange at the plasma membrane(PM).Plasma membrane proteins mediate such communication,by sensing variations in nutrient availability,external cues as well as by controlled solute transport across the membrane border.Localization and steady‐state levels are essential for PM protein function and ongoing research identifed cis‐and trans‐acting determinants,involved in control of plant PM protein localization and turnover.In this overview,we summarize recent progress in our understanding of plant PM protein sorting and degradation via ubiquitylation,a post‐translational and reversible modifcation of proteins.We highlight characterized components of the machinery involved in sorting of ubiquitylated PM proteins and discuss consequences of protein ubiquitylation on fate of selected PM proteins.Specifcally,we focus on the role of ubiquitylation and PM protein degradation in the regulation of polar auxin transport(PAT).We combine this regulatory circuit with further aspects of PM protein sorting control,to address the interplay of events that might control PAT and polarized growth in higher plants. | Barbara Korbei Christian Luschnig | 2013 | Journal of Integrative Plant Biology2013，55，9： | 3 |
| 4 | Serpentine and vermiform encode matrix proteins with chitin-binding and deacetylation domains that limit tracheal tube length in Drosophila显示文摘 | Luschnig S Batz T Armbruster K | 2006 | Curr Biol2006，16，2： | 1 |
| 5 | Serpentine and ver miform encode matrix proteins with chitin-binding and deacety lation domains that limit tracheal tube length in Drosophila 显示文摘 | Luschnig S Batz T Armbruster K | 2006 | Curr Biol2006，16，： | 1 |
| 6 | CRTH2and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases显示文摘 | SCHULIGOI R1 STURM E LUSCHNIG P | 2010 | Pharmacology2010，85，： | 1 |
| 7 | Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity 显示文摘 | SAUER M BALLA J LUSCHNIG C | 2006 | Genes g Development2006，20，20： | 1 |
| 8 | Arabidopsis thaliana RAD6 homolog AtUBC2 complements UV sensitivity,but not N-end rule degradation deficiency,of Saccharomyces cerevisiae tad6 mutants显示文摘 | ZWIRN P STARY S LUSCHNIG C | 1997 | Current Genetics1997，32，5： | 1 |
| 9 | Auxin transport:ABC proteins join the club显示文摘 | | 2002 | Trends Plant Sci2002，7，8： | 1 |
| 10 | Arabidopsis thaliana RAD6homolog AtUBC2 complements UV sensitivity, but not N-end ruledegradation deficiency, of Saccharomyces cerevisiae rad6 mutants显示文摘 | Zwim P Stary S Luschnig C | 1997 | Current genetics1997，32，5： | 1 |
| 11 | serpentine and vermiform encode matrix proteins with chitin binding and deacetylation domains that limit tracheal tube length in Drosophila显示文摘 | Luschnig S BtzT Armbruster K | 2006 | Curt Biol2006，16，2： | 1 |
| 12 | Arabidopsis thaliana RAD6 homolog AtUBC2 complements UV sen- sitivity, but not N-end rule degradation defi- ciency, of Saccharomyces cerevisiae rad6 mutants 显示文摘 | Zwim P Stary S Luschnig C | 1997 | Current Genetics1997，32，5： | 1 |
| 13 | The Arabidopsis MAX Pathway Controls Shoot Branching by Regulating Auxin Transport显示文摘 | Tom Bennett Tobias Sieberer Barbara Willett Jon Booker Christian Luschnig Ottoline Leyser | 2006 | Current Biology2006，，6： | 1 |
| 14 | Auxin transport: ABC proteins join the club显示文摘 | Luschnig C | 2002 | Trends in Plant Science2002，7，8： | 1 |
| 15 | Canalization of auxin flow byAux/IAA-ARF-dependent feedback regulation of PIN polarity显示文摘 | Sauer M Balla J Luschnig C | 2006 | Genes Dev2006，20，： | 1 |
| 16 | Serpentine and vermiform encode matrix proteins with chitin binding and deacetylation domains that limit tracheal tube length in Drosophila显示文摘 | LUSCHNIG S BATZ T ARMBRUSTER K | 2006 | Curt Biol2006，16，2： | 1 |
| 17 | Serpentine and vermiform encode matrixproteins with chitin binding and deacetylation domains that limit tracheal tube length in Drosophila显示文摘 | Luschnig S Batz T Armbruster K | 2006 | Current Biology2006，16，： | 1 |
| 18 | Pho-view of Auxin:Reversible Protein Phosphorylation in Auxin Biosynthesis,Transport and Signaling显示文摘The phytohormone auxin plays a central role in shaping plant growth and development.With decades of genetic and biochemical studies,numerous core molecular components and their networks,underlying auxin biosynthesis,transport,and signaling,have been identified.Notably,protein phosphorylation,catalyzed by kinases and oppositely hydrolyzed by phosphatases,has been emerging to be a crucial type of post-translational modification,regulating physiological and developmental auxin output at all levels.In this review,we comprehensively discuss earlier and recent advances in our understanding of genetics,biochemistry,and cell biology of the kinases and phosphatases participating in auxin action.We provide insights into the mechanisms by which reversible protein phosphorylation defines developmental auxin responses,discuss current challenges,and provide our perspectives on future directions involving the integration of the control of protein phosphorylation into the molecular auxin network. | Shutang Tan Christian Luschnig Jiri Friml | 2021 | Molecular Plant2021，14，1： | 1 |
| 19 | EIR1,a root-specific protein involved in auxin transport,is required for gravitropism in Arabidopsis thaliana显示文摘 | LUSCHNIG C GAXIOLA R A GRISAFI P | | 0，，14： | 1 |
| 20 | Arabidops: thdiana RAD6 homolog AtUBC2 complements UV sensitivity, but not N-end rule degradation defi-ciency, of Saccharomyces cerevisiae rad6 mutants 显示文摘 | Zwirn P Stary S Luschnig C | 1997 | Curr Oenet1997，32，： | 1 |
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