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| 1 | Dual inhibition of EGFR at protein and activity level via combinatorial blocking of PI4KIla as anti-tumor strategy显示文摘 | Jiangmei Li Lunfeng Zhang Zhen Gao Hua Kang Guohua Rong Xu Zhang Chang Chen | 2014 | Protein & Cell2014，5，6： | 2 |
| 2 | SNObase,a database for S-nitrosation modification显示文摘S-Nitros(yl)ation is a ubiquitous redox-based post-translational modification of protein cysteine thiols by nitric oxide or its derivatives,which transduces the bioactivity of nitric oxide(NO)by regulation of protein conformation,activity,stability,localization and pro-tein-protein interactions.These years,more and more S-nitrosated proteins were identified in physiological and pathological processes and the number is still growing.Here we developed a database named SNO-base(http://gffzz0fe23e43c53446d5hkvf6vkcpnpfx6qop.ffgz.tsg.suse.edu.cn),which collected S-nitrosation targets extracted from literatures up to June 1st,2012.SNObase contained 2561 instances,and provided information about S-nitrosation targets,sites,biological model,related diseases,trends of S-nitrosation level and effects of S-nitrosation on protein function.With SNObase,we did functional analysis for all the SNO targets:In the gene ontology(GO)biological process category,some processes were discovered to be related to S-nitrosation(“response to drug”,“regulation of cell motion”)besides the previously reported related processes.In the GO cellular component category,cytosol and mitochondrion were both enriched.From the KEGG pathway enrichment results,we found SNO targets were enriched in different diseases,which suggests possible significant roles of S-nitrosation in the progress of these diseases.This SNObase means to be a database with precise,comprehensive and easily accessible information,an environment to help researchers integrate data with comparison and relevancy analysis between different groups or works,and also an SNO knowledgebase offering feasibility for systemic and global analysis of S-nitrosation in interdisciplinary studies. | Xu Zhang Bo Huang Lunfeng Zhang Yuying Zhang Yingying Zhao Xiaofei Guo Xinhua Qiao Chang Chen | 2012 | Protein & Cell2012，3，12： | 2 |
| 3 | Comparative Study of Outcome in Treating Upper Ureteral Impacted Stones Using Minimally Invasive Percutaneous Nephrolithotomy With Aid of Patented System or Transurethral Ureteroscopy显示文摘 | Zhongsheng Yang Leming Song Donghua Xie Min Hu Zuofeng Peng Tairong Liu Chuance Du Jiuqing Zhong Wen Qing Shulin Guo Lunfeng Zhu Lei Yao Jianrong Huang Difu Fan Zhangqun Ye | 2012 | Urology2012，，6： | 1 |
| 4 | Clinical application of flexible ureteroscopic sheath with controllable intraluminal pressure in treating ureteral stones显示文摘Objective:The purpose of the study was to assess the clinical efficacy and safety of a combined perfusion suction platform with pressure feedback control function and an ureteroscopic suction sheath that can measure the ureteropelvic pressure in implementing lithotripsies.Methods:Fifty-two patients who underwent lithotripsy under intelligent monitoring of ureteral intraluminal pressure from June 2016 to January 2018 were retrospectively recruited.The inclusion standard was stone diameter>1.5 cm but<2.5 cm.After the 12/14 Fr suction sheath was placed,manometer interface and suction interface of the sheath were connected to the platform via the pressure sensor and suction tube,respectively.The ureteroscope was connected to the platform perfusion pump,and the crushed stones were aspirated out under negative pressure.Results:According to the location of the stone,21(40.4%)cases were classified as upper ureteral stones,19(36.5%)were midureteral stones,and 12(23.1%)were lower ureteral stones.Forty-seven patients underwent successful primary sheath placement and lithotripsy with a mean operative time of 34.5(standard deviation 18.3)min.Retrograde stone migration did not occur.There were eight patients with hematuria postoperatively.Serious complication was 1.9% with one case of ureteral perforation.Stone clearance was 95.7% at Day 1e2 postoperatively,and 100% at Day 30 postoperatively.Conclusion:Ureteroscopic lithotripsy with intelligent pressure control using our device improved the efficiency of the lithotripsy and rate of stone clearance.The safety of the operation can be ensured.It is worth popularization and application in clinical practice. | Yuming Zhong Donghua Xie Chunxiang Luo Xiaohui Liao Tairong Liu Xiaoling Deng Lunfeng Zhu Leming Song | 2023 | Asian Journal of Urology2023，10，2： | 1 |
| 5 | PI4KIIα regulates insulin secretion and glucose homeostasis via a PKD-dependent pathway显示文摘 | Lunfeng Zhang Jiangmei Li Panpan Zhang Zhen Gao Yingying Zhao Xinhua Qiao Chang Chen | 2018 | Biophysics Reports2018，4，1： | 1 |
| 6 | Low-Temperature Synthesis of r-MnO2 Hollow Urchins and Their Application in Rechargeable Li+ Batteries显示文摘 | Benxia Li Guoxin Rong Yi Xie Lunfeng Huang and Chuanqi Feng | 2006 | Inorganic chemistry2006，，45： | 1 |
| 7 | Comparative Study of Outcome in Treating Upper Ureteral Impacted Stones Using Minimally Invasive Percutaneous Nephrolithotomy With Aid of Patented System or Transurethral Ureteroscopy显示文摘 | Zhongsheng Yang Leming Song Donghua Xie Min Hu Zuofeng Peng Tairong Liu Chuance Du Jiuqing Zhong Wen Qing Shulin Guo Lunfeng Zhu Lei Yao Jianrong Huang Difu Fan Zhangqun Ye | 2012 | Urology2012，，6： | 1 |
| 8 | Graphics Innovation Design Based on Cell Intuition Simulation Method显示文摘This paper proposes a new cell intuition simulation method which is a combination of intuitive simulation calculation method and the operation of binary image,and applied it in the innovation of the graphic design process.First of all,we study how to express a variety of graphics,and establish the definition of cell intuitive model,work out the cell intuitive operation process and many new cellular operators such as a variety of matrix blocks crossover operator,a variety of matrix blocks mutation operator,matrix blocks replace operator,matrix blocks compression operator,matrix blocks extension operator.By choosing two or more cells and selecting the artificial selection or fitness selection,we can set up and visualize the design and pick the best design results.Finally,validation is made on this algorithm by an example,and a innovation graphic is also represented. | XIA Zhi-qiu REN Na ZHAO Ting-ting CUI Lunfeng | 2014 | Computer Aided Drafting,Design and Manufacturing2014，24，1： | 0 |
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