维普中文期刊产品整合服务
123篇 您的检索式:作者名="Lubsen"
    题名 作者 年代 出处 被引量
1基于一个大型随机试验预测稳定性心绞痛队列患者死亡、心肌梗死和卒中的危险评分显示文摘目的对需要抗心绞痛治疗并且左心室功能代偿症状稳定的心绞痛患者建立预测全因死亡、心肌梗死和导致致残性卒中的复合危险评分。设计大型多中心临床试验数据的多变量Cox回归分析。背景西欧、以色列、加拿大、澳大利亚和新西兰的心脏专科门诊患者。入选者7311例具有全部需要资料的患者被入选。主要结局的测量指标平均随访4.9年时间内所有原因的死亡、心肌梗死或者致残性卒中。结果1063例患者发生任何原因死亡或者持久性心肌梗死或者致残性卒中。这些复合终点的5年危险性在危险性最低的十分位患者为4%,而在危险性最高的十分位患者为35%。危险评分结合16项临床常规变量的降序排序是:年龄、左心室射血分数、吸烟、白细胞计数、糖尿病、随机血糖浓度、肌酐浓度、既往卒中病史、1周至少1次心绞痛发作、冠状动脉造影发现(如果能够获得)、降脂治疗、QT间期、收缩期血压≥150mmHg、抗心绞痛药物数量、陈旧性心肌梗死以及性别。把这个模型分别应用于任何原因所致的死亡、心肌梗死和卒中进行预测评估,所得的结果相似。危险评分似乎不能预测事件性质(39%的死亡、46%心肌梗死以及15%致残性卒中)或者冠状动脉造影或血管重建率(占29%的患者)。结论该危险评分对客观地决定稳定性心绞痛患者进一步治疗措施以减少重要预后事件发生是有帮助的。该危险评分同样可以用于将来的计划性试验。Tim C Clayton Stuart J Pocock Jacobus Lubsen Zoltán Vokó Bridget-Anne Kirwan Keith A A Fox Philip A Poole-Wilson 2006英国医学杂志中文版2006,9,1:2
2Efficacy of nifedipine and metoprolol in the early treatment of unstable angina in the coronary care unite:findings from the Holland Interuniversity Nifedipine/metoprolol Trial(HINT)显示文摘Lubsen J Tisjssen JG 1987Am J Cardiol1987,60,2:1
3Effect of long-acting nifedilpine on mortality and cardiovascular mortality in patients with symptomatic stable angina and hypertension:the ACTION trial显示文摘Lubsen J Wagener G Kirwan BA 2005J Hypertens2005,23,:1
4Effect of long-acting nifedipine On mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension:the ACTION trial显示文摘Lubsen J Wagener G Kirwan BA et a1 2005J Hypertens2005,23,3:1
5Risk factors for seizure fecurrence in childre with febrile seizures: A pooled analysis of divedual data from five studies显示文摘Offringa M Bossuyt PM Lubsen J 1994J Pe- diatr1994,124,4:1
6Clinical implications of laryngeal amyloidosis 显示文摘Gramans K Lubsen H 1985J Laryngol Otol1985,99,6:1
7Risk management in cardiology显示文摘 Poole-Wilson PA 2000Eur Heart J2000,2,:1
8Extra lenticular expression of Xenopus laevis α,β,and γ-crystalline gene显示文摘Brundereef GA van Genesen ST Destree OHJ Lubsen NH 1997Invest Ophthalmol Vis Sci1997,38,:1
9Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment ( ACTION trial) : randomised controlled trial 显示文摘Poole-Wilson PA Lubsen J Kirwan BA 2004Lancet2004,364,:1
10Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial) : randomized con- trolled triM显示文摘Poole-Wilson PA Lubsen J Kinsan RA 2004Lancet2004,364,9437:1
11Vascular permeability factor expression influences tumor angiogenesis in human melanoma lines xenografted to nude mice显示文摘Potgens AJ Lubsen NH van Altena MC 1995Am J Pathol1995,146,:1
12Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with syptomatie stable angiana and hypertension: the ACTION trial显示文摘Lubsen J Wagener G Kirwan BA 2005Hypertens2005,23,3:1
13Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension : the A CTION trial 显示文摘Lubsen J Wagener G Kirwan BA 2005J Hypertens2005,23,:1
14Salivary gland carcinoma:independent prognostic factors for locoregional control,distant metastases,and overall survival:results of the Dutchhead and neck oncology cooperative group显示文摘Terhaard CH Lubsen H Van der Tweell 2004Head Neck2004,26,8:1
15Nifedipine and metoprolol in unstable angina: findings from the Holland Interuniversity Nifedipine/metoprolol Trial (HINT)显示文摘Tijssen JG Lubsen J 1987J Cardiovasc Pharmacol1987,102,:1
16Risk factors for seizure fecurrence in children with febrile seizures:A pooled analysis of individual patient data from five studies显示文摘Offringa M Bossuyt PM Lubsen J 1994J Pediatr1994,124,4:1
17Effect of longacting nifedipineon mortality and cardiovascular morbidity in patients with stableangina requiring treatment(ACTION trial):randomised controlledtrial显示文摘Wilson PA Lubsen J Kirwan BA 0,,03:1
18Effect of simvastatin on coronary atheroma: the Mult icentre Anti- Atheroma Study (MAAS) 显示文摘Oliver MF de Feyter PJ Lubsen J 1994Lancet1994,,334:1
19Effect of long-acting nifedipine on mortality andcardiovascular morbidity in patients with symptomatic stable angina and hypertension:the ACTION trial显示文摘Lubsen J Wagener G Kirwan BA 2005J Hypertens2005,23,3:1
20Microstructural and functional connectivity in the developing preterm brain显示文摘Lubsen J Vohr B Myers E Hampson M Lacadie C Schneider KC 2011Semin Neonatol2011,35,1:1
返回顶部 每页显示:
共7页 首页 上一页 第1页 下一页 末页 /7 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费