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| 1 | Research on optimized GA-SVM vehicle speed prediction model based on driver-vehicle-road-traffic system显示文摘The accurate prediction of vehicle speed plays an important role in vehicle's real-time energy management and online optimization control. However, the current forecast methods are mostly based on traffic conditions to predict the speed, while ignoring the impact of the driver-vehicle-road system on the actual speed profile. In this paper, the correlation of velocity and its effect factors under various driving conditions were firstly analyzed based on driver-vehicle-road-traffic data records for a more accurate prediction model. With the modeling time and prediction time considered separately, the effectiveness and accuracy of several typical artificial-intelligence speed prediction algorithms were analyzed. The results show that the combination of niche immunegenetic algorithm-support vector machine(NIGA-SVM) prediction algorithm on the city roads with genetic algorithmsupport vector machine(GA-SVM) prediction algorithm on the suburb roads and on the freeway can sharply improve the accuracy and timeliness of vehicle speed forecasting. Afterwards, the optimized GA-SVM vehicle speed prediction model was established in accordance with the optimized GA-SVM prediction algorithm at different times. And the test results verified its validity and rationality of the prediction algorithm. | LI YuFang CHEN MingNuo LU XiaoDing ZHAO WanZhong | 2018 | Science China(Technological Sciences)2018，61，5： | 5 |
| 2 | A NOVEL ALGORITHM FOR SIDE PEAKS SUPPRESSION OF AMBIGUITY FUNCTION FOR PASSIVE RADAR BASED ON CHINESE DTTB SIGNAL显示文摘The ambiguity function of Chinese standard Digital Television Terrestrial Broadcasting (DTTB) signals for passive radar contains one main peak and many side peaks. The side peaks may cause the false alarms. The relative positions and the reasons for the side peaks are analyzed and a new algorithm for side peaks suppression is proposed in this paper. The algorithm, in consideration of the characteristics of the structure of the frame, can eliminate the side peaks completely in the valid Doppler observation interval by setting the reference signals to zero at equal intervals. Both the simulative and experimental results show that this algorithm can improve the performance of target detection of the passive radar based on DTTB signal. | Li Jichuan Lu Xiaode Zhao Yaodong | 2012 | Journal of Electronics(China)2012，29，6： | 5 |
| 3 | Car-following behavior modeling driven by small data sets based on mnemonic extreme gradient boosting framework显示文摘Dear editor,In recent years,data-driven car-following models have been developed based on their ability to drill down to information in driving data and their flexibility.According to a study by Fleming et al.[1],the main limitation of existing methods is an insufficient amount of natural driving data.In addition,there are many situations during actual driving processes,such as those under extreme conditions[2]and in the early stages of car-following behavior modeling.In these cases,sparse data learning algorithms are indispensable. | Baichuan LOU Yufang LI Xiaoding LU Zhe XU | 2022 | Science China(Information Sciences)2022，65，6： | 2 |
| 4 | Integrating run-based preventive maintenance into the capacitated lot sizing problem with reliability constraint 显示文摘 | Lu Zhiqiang Zhang Yuejun Han Xiaode | 2013 | In- ternational Journal of Production Research2013，51，5： | 1 |
| 5 | Nanopores/Nanochannels Based on Electrical and Optical Dual Signal Response for Application in Biological Detection显示文摘Cancers and chronic diseases have always been global health problems. The occurrence and development of such diseases are closely related to the abnormalities of proteins, nucleic acids, ions or small molecules in the body. Nowadays, nanopores/nanochannels have emerged as a powerful platform for detecting these biomolecules based on the electrical signal variation caused by biomolecules passing. However, detection relied on the electrical signal easily suffered from the clogging defects, low throughput, and strong background signals. Fortunately, the emergence of designing nanopores/nanochannels based on electrical and optical dual signal response has brought innovative impetus to biological detection, which can also identify the chemical compositions and conformations of the biomolecules. In this review, we summarize the reasonable preparation of nanopores/nanochannels with electrical and optical dual signal response and their application in biological detection. According to different biomolecules, we divide the targets into four types, including nucleic acids, small molecules, ions and proteins. In each section, the design of representative examples and the principle of dual signal generation are introduced and discussed. Finally, the prospects and challenges of nanopores/nanochannels based on electrical and optical dual signal response are also discussed. | Guangwen Lu Niya Lin Zhaojun Chen Wenlian Jiang Jing-Jing Hu Fan Xia Xiaoding Lou | 2023 | Chinese Journal of Chemistry2023，41，11： | 1 |
| 6 | Nanoparticles (NPs)-mediated Siglec15 silencing and macrophage repolarization for enhanced cancer immunotherapy显示文摘cell infiltration and proliferation in tumor tissues are the main factors that significantly affect the therapeutic outcomes of cancer immunotherapy.Emerging evidence has shown that interferon-gamma(IFN)could enhance CXCL9 secretion from macrophages to recruit T cells,but Siglec15 expressed on TAMs can attenuate T cell proliferation.Therefore,targeted regulation of macrophage function could be a promising strategy to enhance cancer immunotherapy via concurrently promoting the infiltration and proliferation of T cells in tumor tissues.We herein developed reductionresponsive nanoparticles(NPs)made with poly(disulfide amide)(PDSA)and lipid-poly(ethylene glycol)(lipid-PEG)for systemic delivery of Siglec15 siRNA(siSiglec15)and IFN for enhanced cancer immunotherapy.After intravenous administration,these cargo-loaded could highly accumulate in the tumor tissues and be efficiently internalized by tumor-associated macrophages(TAMs).With the highly concentrated glutathione(GSH)in the cytoplasm to destroy the nanostructure,the loaded IFN and si-Siglec15 could be rapidly released,which could respectively repolarize macrophage phenotype to enhance CXCL9 secretion for T cell infiltration and silence Siglec15 expression to promote T cell proliferation,leading to significant inhibition of hepatocellular carcinoma(HCC)growth when combining with the immune checkpoint inhibitor.The strategy developed herein could be used as an effective tool to enhance cancer immunotherapy. | Xiaodi Liu Qi Zhang Yixia Liang Shiyu Xiong Yan Cai Jincheng Cao Yanni Xu Xiaolin Xu Ye Wu Qiang Lu Xiaoding Xu Baoming Luo | 2023 | Acta Pharmaceutica Sinica B2023，13，12： | 0 |
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