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| 1 | EXPERIMENTAL INVESTIGATION AND COMPUTER SIMULATION ON DYNAMIC BUCKLING BEHAVIOR OF LIQUID-FILLED CYLINDRICAL SHELLS UNDER AXIAL IMPACT显示文摘This article reports an experimental investigation on the axial impact buckling of thin metalliccylindrical shells fully filled with water.Low velocity impact tests are carried out by DHR-9401 drop hammerrig.The whole process of dynamic buckling is simulated using LS-DYNA computer code.The consistencybetween experimental observation and numerical simulation is quite satisfactory.The investigation indieatesthat quite high internal hydrodynamic pressure occurs inside the shell during the impact process.Under thecombined action of the high internal pressure and axial compression plastic buckling occurs easily in the thin-walled shells and buckling modes take on regular and axisymmetric wrinkles. | Zhang, SY Lei, JP Zhao, LM Cheng, GQ Lu, GY | 2000 | Acta Mechanica Solida Sinica2000，13，2： | 2 |
| 2 | TSC1-mTOR-PLK轴以阶段特异性方式调节从施旺细胞增殖到髓鞘形成的内稳态开关显示文摘恰如其分的外周髓鞘形成取决于雪旺细胞增殖与分化进程间的平衡。丝氨酸/苏氨酸激酶(mTOR)整合多种环境因素,是细胞生长、代谢、发挥作用的中枢调节者。本文报道了一种mTOR的负性调节剂——结节性硬化复合体(TSC1),通过控制细胞增殖和髓鞘稳态,建立了雪旺细胞谱系进展和髓鞘形成的阶段依赖性程序。小鼠雪旺细胞祖细胞中TSC1的解离导致mTOR信号通路激活,继而导致雪旺细胞过量增殖,分化受阻,髓鞘形成减少。转录组分析显示,TSC1突变体中的mTOR活化使得polo样激酶(PLK)依赖性通路和细胞周期调节剂上调。弱化mTOR或者对PLK进行药理抑制部分挽救了因TSC1缺失导致的外周神经发育过程中的髓鞘形成减少。相较之下,成年小鼠成熟雪旺细胞中TSC1缺失可导致髓鞘的过度增殖和过度生长。本文的发现提示了TSC1-mTOR-PLK信号轴在控制雪旺细胞的发育过程中,从增殖到分化和髓鞘内稳态中起到的阶段特异性功能。 | Jiang M Rao R Wang J Wang J1 Xu L Wu LM Chan JR Wang H Lu QR 聂昊(编译) | 2018 | 神经损伤与功能重建2018，13，5： | 2 |
| 3 | Molecular dynamics simulation of RGD peptide adsorption on titanium oxide surfaces显示文摘 | Zhang H P Lu X LM Fang | 2008 | J Mater Sci:Mater Med2008，19，： | 1 |
| 4 | Akt activation induced by lysophosphatidic acid and sphingosine-l-phosphate requires both mitogen-activated protein kinase and p38 mimtogen-activated protein kinase and is cell-line specific显示文摘 | Baudhuin LM Cristina KL Lu J | 2002 | Mol Pharmacol2002，62，3： | 1 |
| 5 | The mechanical properties ofβ-Si3N4whiskers-reinforced dental resin composites显示文摘 | Zuo KH Lu LM Zeng YP | 2014 | J Applied Polymer Sci2014，131，40： | 1 |
| 6 | Oxidative stress augments the production of matrix metallop rotei -nase-1, cyclooxygenase-2, and prostaglandin E2 through enhancement of NF- kappa B ac- tivity in lipopolysaccharide-activated human primary mono- cytes显示文摘 | Lu Y Wahl LM | 2005 | JImmunol2005，175，8： | 1 |
| 7 | Double blind randomized multicentre study of the efficacy and safety of gliclazide modified release in the treatment of Chinese type 2 diabetic patients显示文摘 | Lu CH Chang CC Chuang LM | 2006 | Diabetes Obes Metab2006，8，2： | 1 |
| 8 | Clinical features and factors of unfavorable outcomes for non-polio enterovirus in- fection of the centeral nervous system in northern Taiwan, 1994- 2003 显示文摘 | Yang TT Huang LM Lu CY | 2005 | J MicrobiolImmunol Infect2005，38，6： | 1 |
| 9 | Role of hydroxyl radical in silica- induced NF- kappa Bactivaton in macrophages 显示文摘 | Chen F Lu Y Demers LM | 1998 | Ann Clin Lab Sci1998，28，1： | 1 |
| 10 | The primary hamster kidney cell rabies vaccine: adaption of viral strain, production of vaccine,and postexposure treatment显示文摘 | Lin FT Zeng FZ Lu LM | 1983 | J Infect Dis1983，147，3： | 1 |
| 11 | Clinical features and factors of unfavorable outcomes for non polio enterovirus infection of the central nervous system in northern Taiwan, 1994-2003显示文摘 | Yang TT Huang LM Lu CY | 2005 | Journal of Microbiology Infect2005，38，6： | 1 |
| 12 | Assembly and development of the Pseudomonas aeruginosa biofilm matrix显示文摘 | Ma LM Conover M Lu H | 2009 | Plos Pathogens2009，5，10： | 1 |
| 13 | Outbreak of lower respiratory tract illness associatedwith human enterovirus 68 among American Indian children显示文摘 | Jacobson LM Redd JT Schneider E Lu X Chern SW ObersteMS | 2012 | Pediatr Infect Dis J2012，31，3： | 1 |
| 14 | Atypical hand foot- mouth disease in children: a hospital based prospective cohort study显示文摘 | Huang WC Huang LM Lu CY | 2013 | Virol J2013，10，： | 1 |
| 15 | Hand,foot and mouth disease complicated with central nervous system involvement in Taiwan in 1980-1981显示文摘 | Chang LY Lee CY Kao CL Fang TY Lu CY Lee FI Huang LM | 2007 | J Formos Med Assoc2007，106，2： | 1 |
| 16 | Sixty-four-row multisection CT angiography for detection and evaluation of ruptured intractanial aneurysms:intcrubserver and interchnique reproducibility显示文摘 | Lu B LM Francois O | | 201 00，，10： | 1 |
| 17 | A framework for the development of maternal quality of care indicators 显示文摘 | Korst LM Gregory KD Lu MC | 2005 | Mater-nal and Child Health Journal2005，9，3： | 1 |
| 18 | A pooled analysis of diffusion- weighted imaging in the diagnosis of hepatocellular carcinoma in chronic liver diseases显示文摘 | Wu LM Xu JR Lu Q | 2013 | J Gastroenterol Hepatol2013，28，： | 1 |
| 19 | Macrolide-linco samide-resistant phenotypes and genotypes of Staphylococcus aureus isolated from bovine clinical mastitis显示文摘 | Wang Y Wu CM Lu LM | 2008 | Vet Microbiol2008，130，12： | 1 |
| 20 | Hepatitis B virus infection, its sequelae, and prevention by vaccination 显示文摘 | Huang LM Lu CY Chen DS | 2011 | Current Opinion in Immunology2011，23，2： | 1 |
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