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| 1 | Risk of cardiovascular,cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)has emerged as a public health problem of epidemic proportions worldwide.Accumulating clinical and epidemiological evidence indicates that NAFLD is not only associated with liver-related morbidity and mortality but also with an increased risk of coronary heart disease(CHD),abnormalities of cardiac function and structure(e.g.,left ventricular dysfunction and hypertrophy,and heart failure),valvular heart disease(e.g.,aortic valve sclerosis)and arrhythmias(e.g.,atrial fibrillation).Experimental evidence suggests that NAFLD itself,especially in its more severe forms,exacerbates systemic/hepatic insulin resistance,causes atherogenic dyslipidemia,and releases a variety of pro-inflammatory,pro-coagulant and pro-fibrogenic mediators that may play important roles in the pathophysiology of cardiac and arrhythmic complications.Collectively,these findings suggest that patients with NAFLD may benefit from more intensive surveillance and early treatment interventions to decrease the risk for CHD and other cardiac/arrhythmic complications.The purpose of this clinical review is to summarize the rapidly expanding body of evidence that supports a strong association between NAFLD and cardiovascular,cardiac and arrhythmic complications,to briefly examine the putative biological mechanisms underlying this association,and to discuss some of the current treatment options that may influence both NAFLD and its related cardiac and arrhythmic complications. | Stefano Ballestri Amedeo Lonardo Stefano Bonapace Christopher D Byrne Paola Loria Giovanni Targher | 2014 | World Journal of Gastroenterology2014，20，7： | 55 |
| 2 | Early life stress downreg- ulates endothelin receptor expression and enhances acute stress- mediated blood pressure responses in adult rats 显示文摘 | Loria AS D'Angelo G Pollock DM | 2010 | Am J Physiol Regul Integr Comp Physio12010，299，1： | 1 |
| 3 | Circulating 92-kilodalton Matrix Metalloproteinase(MMP-9) Activity is Enhanced in the Euglobulin Plasma Fraction of Head and Neck Squamous Cell Carcinoma显示文摘 | Ranuncolo S M Matos E Loria D | 2002 | Cancer2002，94，5： | 1 |
| 4 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen显示文摘 | Shiau AK Barstad D Loria PM | 1998 | Cell1998，95，7： | 1 |
| 5 | Initial clinical experi-ence using a novel laparoscopy assistant 显示文摘 | Mishra R Martinez AM Lorias Espinoza D | 2011 | Minim invasive ther al-lied technol2011，20，3： | 1 |
| 6 | A nested Matrosov theorem and persistency of excitation for uniform convergence in stable nonautonomous systems显示文摘 | Loria A Panteley E Popovic D Teel A R | 2005 | IEEE Transactions on Automatic Control2005，50，： | 1 |
| 7 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen显示文摘 | Shiau AK Barstad D Loria PM | | 0，，7： | 1 |
| 8 | Ovine mycoplasmal infections 显示文摘 | Nicholas R A J Ayling R D Loria G R | 2008 | Small Rumin Res2008，76，12： | 1 |
| 9 | The structural basis of estrogen receptor/coactivator re- cognition and the antagonism of this interaction by tamoxifen 显示文摘 | SHIAU A K BARSTAD D LORIA P M | 1998 | Cell1998，95，7： | 1 |
| 10 | The structural basis of oestrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen显示文摘 | Shiau A K Barstad D Loria P M | 1998 | Cell1998，95，7： | 1 |
| 11 | PCR-RFLP identification of Bemisia tabaci biotypes in the mediterranean basin显示文摘 | Bosco D Loria A Sartor C | 2006 | Phytoparasitica2006，34，3： | 1 |
| 12 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen 显示文摘 | Shiaa AK Barstad D Loria PM | 1998 | Cell1998，95，7： | 1 |
| 13 | Characterization of 'basparin A,'a prothrombin-activating metalloproteinase,from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis显示文摘 | Loria G D Alexandra R | 2003 | Biochemistry and Biophysics2003，418，1： | 1 |
| 14 | Survival of inoculum of the entomopathogenic fungus Beauveria bassiana as influenced by fungicides 显示文摘 | Loria R S Galaini S Roberts D W | 1983 | Environ Entomol1983，12，： | 1 |
| 15 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen 显示文摘 | Shiau AK Barstad D Loria PM | 1998 | Cell1998，95，7： | 1 |
| 16 | Endocrine regulation of mttrine macrephage function: effects of dehydroepiandrosterene, androstenediol, and androstenetriol显示文摘 | PADGETT D A LORIA R M | 1998 | Neuroimmunol1998，84，1： | 1 |
| 17 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen显示文摘 | Shiau A K Barstad D Loria P M | 1998 | Cell1998，95，7： | 1 |
| 18 | Nuclear magnetic resonance methods for quantifying microsecond-to millisecond motions in biological macromolecules显示文摘 | Palmer A G III Kroenke C D Loria J P | 2001 | Methods Enzymol2001，339，： | 1 |
| 19 | Effects of potato cultivar and time of harvest on the severity of silver scurf显示文摘 | Merida C L Loria R and Halseth D E | 1994 | Plant Disease1994，78，： | 1 |
| 20 | ct-Linolenic acid prevents the hyperchol- esteremic effects of cholesterol addition to a corn oil diet显示文摘 | Loria R M Padgett D A | 1997 | Nu- tritional Biochemistry1997，8，3： | 1 |
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