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| 1 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016，22，20： | 7 |
| 2 | Selective sphincteroplasty of the papilla in cases at risk due to atypical anatomy显示文摘AIM: To analyze the indications, effi cacy and safety of sphincteroplasty in our centre. METHODS: A retrospective study of sphincteroplasty in 53 cases of papilla at high risk was performed in 2004-2006. The procedure consisted of duodenoscopy with Olympus TJF 145 Videoduodenoscope, approach to the biliary tract using a catheter with a guidewire, and dilatation of the papilla with a dilatation balloon catheter using a syringe with a manometer for control of the fi lling pressure. RESULTS: The indications included intradiverticular papilla in 26 patients (49/), stenosis of a previous sphincterotomy in 19 patients (35.8/), small size of the papilla in 4 patients (7.5/), Billroth Ⅱ gastrectomy in 3 patients (5.6/), and coagulopathy in one patient (1.9/). The efficacy was 97.8/, with all the calculi extracted from the common bile duct in 84.4/ of the patients, even though 21 of the patients (39.6/) had calculi with a diameter equal to or greater than 10 mm. Seven patients (13.2/) presented complications: haemorrhage in 1 patient (1.9/) and mild pancreatitis in 6 patients (11.3/). The mean hospital stay in case of complications was of 3 ± 0.63 d. CONCLUSION: Sphincteroplasty is highly effective, with a complication rate similar to that of sphincterotomy, furthermore, the complications are of low clinical importance. The use of the 10 mm balloon makes it possible to extract calculi with a diameter of over 15 mm and to extract more than 3 calculi without increasing the rate of complications and reduces the need to resort tolithotripsy or rescue sphincterotomy. | F Mugica G Urdapilleta A Castiella A Berbiela F Alzate E Zapata L Zubiaurre P Lopez JI Arenas | 2007 | World Journal of Gastroenterology2007，13，22： | 5 |
| 3 | 高血压患者肾素血管紧张素系统阻断的血浆分子标志:肾损害与初发蛋白尿的新预测指标显示文摘蛋白尿是一个与心血管病密切相关的危险因素,也是一般人群的首位死亡原因。虽然已经明确肾素血管紧张素系统(renin-angiotensin system,RAS)阻断剂能延缓高血压患者初发蛋白尿进展、减少蛋白尿排出,但仍不能忽视高血压患者发生初发蛋白尿的比例。 | Baldan-Martin M Mourino-Alvarez L Gonzalez-Calero L Moreno-Luna R Sastre-Oliva T Ruiz-Hurtado G Segura J Lopez JA Vazquez J Vivanco F Alvarez-Llamas G Ruilope LM de la Cuesta F Barderas MG 赵狄 练桂丽 | 2016 | 中华高血压杂志2016，24，6： | 2 |
| 4 | Polymerization of vinyl acetate in ternary microemulsions stabilized with hexadecyhrimethylammonium bromide显示文摘 | LOPEZ R G TREVINO M E SALAZAR L V | 1997 | Polymer Bulletin1997，38，4： | 1 |
| 5 | Experimental and numerical investigation of the effect of spray cutting fluids in high speed miUing显示文摘 | Lopez De Lacalle L N Angulo C Lamikiz A | 2006 | Journal of Materials Processing Technology2006，172，1： | 1 |
| 6 | Determination of multiclass pesticides in food commodities by pressurized liquid extraction using GC-MS/MS and LC-MS/MS 显示文摘 | Frenich A G Salvador I M Vidal J L M Lopez T L | 2005 | Analytical and Bioanalytical Chemistry2005，33，78： | 1 |
| 7 | Query Expansion with a Medical Ontology to Improve a Multimodal Information Retrieval System 显示文摘 | Diaz - Galiano M C Martin - Valdivia M T Urena - Lopez L A | 2009 | Computers in Biology and Medicine2009，39，4： | 1 |
| 8 | Analysis of cellular immune response in pigs recovered from porcine respiratory and reproductive syndrome infection显示文摘 | Lopez F L Domentch N Alvarez B | 1999 | Virus Res1999，64，1： | 1 |
| 9 | Effect of copperion on the motility, viability, acrosome reaction and fertilizing capacity of human spermatozoa in vitro显示文摘 | Roblero L Guadarrama A Lopez T | 1996 | Reprod Fertil Dev1996，8，： | 1 |
| 10 | Kinetic analysis of the thermal degradation of PVC plastisols显示文摘 | Jimenez A Lopez J Torre L | 1999 | Journal of Applied Polymer Science1999，73，6： | 1 |
| 11 | Evidence-based Health Policy-lessons from the Global Burden of Disease Study 显示文摘 | Murray C J L Lopez A D | 1996 | Science1996，274，： | 1 |
| 12 | Breeding cycle of the northern scallop, Argopecten purpuratus (Lamarck, 1819) in southern Chile 显示文摘 | Gonzalez M L Perez M C Lopez D A | 2002 | Aquaculture Research2002，33，11： | 1 |
| 13 | Application of bacteriocins in the control of foodborne pathogenic and spoilage bacteria显示文摘 | GALVEZ A LOPEZ R L ABRIOUEL H | 2008 | Critical Reviews in Biotechnology2008，28，2： | 1 |
| 14 | Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study显示文摘 | Douglas S Berkman Andres G Lescano Robert H Gilman Sonia L Lopez Maureen M Black | 2002 | The Lancet2002，，9306： | 1 |
| 15 | He- patic angiosarcoma: case report and review of literature 显示文摘 | Poggi Maehuca L Ibarra Chirinos O Lopez Del Aguila J | 2012 | Rev Gastroenterol Peru2012，32，3： | 1 |
| 16 | Effect of tall oil fatty acids content on the properties of novel hyperbranched alkyd resins 显示文摘 | Murillo E A Vallejo P P Lopez B L | 2011 | Journal of Applied Polymer Science2011，120，6： | 1 |
| 17 | Efficient Differ-ential Evolution Algorithms for Multimodal Optimal Control Prob-lems 显示文摘 | Lopez C I L van Willigenburg L G van Straten G | 2003 | Applied Soft Computing2003，3，2： | 1 |
| 18 | Business and so- cial reputation: Exploring the concept and main Dimen- sions of corporate reputation 显示文摘 | De Castro G M Lopez J E N Sdez P L | 2006 | Journal of Business Ethics2006，63，4： | 1 |
| 19 | Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers显示文摘 | AMUNOZ E C RODADO J L LOPEZ P | 2000 | American Journal of Clinical Nutrition2000，71，3： | 1 |
| 20 | Colloidal microgels as transdermal delivery systems显示文摘 | Lopez V C Raghavan S L Snowden M J | 2004 | React Funct Polym2004，58，3： | 1 |
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