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| 1 | General review of magnetic resonance elastography显示文摘Magnetic resonance elastography(MRE) is an innovative imaging technique for the non-invasive quantification of the biomechanical properties of soft tissues via the direct visualization of propagating shear waves in vivo using a modified phase-contrast magnetic resonance imaging(MRI) sequence. Fundamentally,MRE employs the same physical property that physicians utilize when performing manual palpation- that healthy and diseased tissues can be differentiated on the basis of widely differing mechanical stiffness. By performing 'virtual palpation ',MRE is able to provide information that is beyond the capabilities of conventional morphologic imaging modalities. In an era of increasing adoption of multi-parametric imaging approaches for solving complex problems,MRE can be seamlessly incorporated into a standard MRI examination to provide a rapid,reliable and comprehensive imaging evaluation at a single patient appointment. Originally described by the Mayo Clinic in 1995,the technique represents the most accurate non-invasive method for the detection and staging of liver fibrosis and is currently performed in more than 100 centers worldwide. In this general review,the mechanical properties of soft tissues,principles of MRE,clinical applications of MRE in the liver and beyond,and limitations and future directions of this discipline-are discussed. Selected diagrams and images are provided for illustration. | Gavin Low Scott A Kruse David J Lomas | 2016 | World Journal of Radiology2016，8，1： | 5 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Conformational disease显示文摘 | Robin W Carrell David A Lomas | 1997 | 1997 (9071)1997，，9071： | 2 |
| 4 | Low cost thin film based piezoresistive MEMS tactile sensor显示文摘 | Wisitsoraat A Patthanasetakul V Lomas T | 2007 | Sensors and Actuators A: Physical2007，139，12： | 1 |
| 5 | Shock-induced neutrophil mediated priming for acute lung injury in mice:divergent effects of TLR-4 and TLR-4/FasL deficiency显示文摘 | Ayala A Chung CS Lomas JL | 2002 | Am J Pathol2002，161，6： | 1 |
| 6 | Use FCC feed pretreating methods to remove sulfur显示文摘 | SHOREY S W LOMAS D A KASOM W H | 1999 | Hydrocarbon Processing1999，，11： | 1 |
| 7 | A comparison of double- focusing sector field ICP-MS, ICP-OES and octopole collision cell 1CP-MS for the high-accuracy determination of calcium in human serum 显示文摘 | Loma A Simpson Ruth Hearn | 2005 | Talanta2005，65，： | 1 |
| 8 | Shock - induced neutrophil mediated priming for acute lung injury in mice:divergent effects of TLR-4 and TLR- 4/FasL deficiency显示文摘 | Ayala A Chung CS Lomas JL | 2002 | Am J Pathol2002，161，6： | 1 |
| 9 | Sulphite and oxida- tive-reductive depolymerization reactions 显示文摘 | Loma A Paterson Sandra E Hill John R | 1997 | Food Chemistry1997，60，2： | 1 |
| 10 | Elevated organic nutrient ratios associated with brown tide blooms of Aureococcus anophagefferens (Pelagophyceae)显示文摘 | LOMAS M W GLIBERT P M CLOUGHERTY D A | 2001 | Journal of Plankton Research2001，23，： | 1 |
| 11 | Shock-induced neutrophil mediated priming for acute lung injury in mice:divergent effects of TLR-4 and TLR-4/FasL deficiency显示文摘 | Ayala A Chung CS Lomas JL | 2002 | Am J Pathol2002，161，6： | 1 |
| 12 | Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort 显示文摘 | Lomas D A Silverman E K Edwards L D etal | 2008 | Thorax2008，63，10： | 1 |
| 13 | Ele-vated organic nutrient ratios associated with brown tide algalblooms of Aureococcus anophagefferens ( Pelagophyceae) 显示文摘 | LOMAS M W GILBERT P M CLOUGHERTY D A | 2001 | Journal of Plankton Research2001，23，12： | 1 |
| 14 | Vegetation-climate feedbacks in a greenhouse world显示文摘 | Woodward F I Lomas M R Betts R A | 1998 | Philosophical Transactions of the Royal Society1998，353，： | 1 |
| 15 | The mechanism of Z alpha 1-antitrypsin accumulation in the liver显示文摘 | LOMAS D A EVANS D L FINCH J T | 1992 | Nature1992，357，6379： | 1 |
| 16 | Molecular mousetraps,alpha1-antitrypsin deficiency and the serpinopathies显示文摘 | LOMAS D A | 2005 | Clin Med2005，5，3： | 1 |
| 17 | A systematic re- view of worldwide incidence of non melanoma skin cancer显示文摘 | Lomas A Leonardi Bee J Bath-Hextall F | 2013 | Br J Dermatolin press2013，11，7： | 1 |
| 18 | MR cholangiopancreatogra- phy: prospective eompa6son of a breath-hohl 2D projection tech- nique with diagnostic ERCP显示文摘 | Lomas D J Bearcroft P W Gimson A E | 1999 | Eur Radiol1999，9，7： | 1 |
| 19 | Synthesis and biological characterisation of novel N-alkyl-deoxynojirimycin α-glucosidases inhibitors 显示文摘 | Rawlings A J Lomas H Pilling A W | 2009 | Chembioehem2009，10，6： | 1 |
| 20 | Total dissolved nitrogen anglysis:Comparisons between persulfate,UV,and high temperature oxidation methods显示文摘 | Bronk D A Lomas M W Glibert P M | 2000 | Marine Chemistry2000，69，： | 1 |
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