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| 1 | Seminal biomarkers for the evaluation of male infertility显示文摘为努力与他们的搭挡一起怀孕的男人,诊断工具被限制并且经常由仅仅标准精液分析组成。这基线测试用作男富饶的一个粗略的评价,离开需要另外的诊断 biomarkers 的病人和临床医生。精液从因此,这评论在某些男不孕情形在当前、新奇的精液的 biomarkers 上集中包括自然富饶,区分精子缺乏病原学,并且预言的繁殖的腺帮助了的男性包含分子的最高的集中繁殖技术成功。当前可得到的测试包括 antisperm 抗体试金, DNA 破碎索引,在 situ 杂交的精子荧光,和另外的历史的精子功能的测试。当前的试金的差的诊断能力导致了继续的努力发现更预兆的 biomarkers。genomics, epigenetics, proteomics, transcriptomics,和为新奇男不孕 biomarkers 的发展的 metabolomics 抓住诺言的地里的新兴的研究。TEX101, ECM1,和 ACRV1 的精液的基于蛋白质的试金已经是可得到的或在为临床的使用的最后的开发中。当我们试图理解男不孕的 pathophysiologic 过程, DNA, RNA,蛋白质,或代谢物的另外的面板正在被探索。未来冒险将需要继续数据集成和确认让临床上有用的不孕 biomarkers 的开发帮助男不孕诊断,处理,并且建议。 | Jared M Bieniek Andrei P Drabovich Kirk C Lo | 2016 | Asian Journal of Andrology2016，18，3： | 15 |
| 2 | Role of stem cell therapies in treating chronic wounds:A systematic review显示文摘BACKGROUND The impairment of cutaneous wound healing results in chronic,non-healing wounds that are caused by altered wound environment oxygenation,tissue injury,and permissive microbial growth.Current modalities for the treatment of these wounds inadequately address the complex changes involved in chronic wound pathogenesis.Consequently,stem cell therapies have emerged as a potential therapeutic modality to promote cutaneous regeneration through trophic and paracrine activity.AIM To investigate current literature regarding use of stem cell therapies for the clinical treatment of chronic,non-healing wounds.METHODS PubMed,EMBASE,Cochrane Library,Web of Science,and Scopus were queried with combinations of the search terms“mesenchymal stem cells,”“adult stem cells,”“embryonic stem cells,”“erythroid precursor cells,”“stem cell therapies,”and“chronic wounds”in order to find relevant articles published between the years of 2000 and 2019 to review a 20-year experience.Reference lists from the articles were reviewed to identify additional pertinent articles.Retrieved manuscripts(reviews,case reports/series,retrospective/prospective studies,and clinical trials)were evaluated by the authors for their depiction of clinical stem cell therapy use.Data were extracted from the articles using a standardized collection tool.RESULTS A total of 43 articles describing the use of stem cell therapies for the treatment of chronic wounds were included in this review.While stem cell therapies have been explored in in vitro and in vivo applications in the past,recent efforts are geared towards assessing their clinical role.A review of the literature revealed that adipose-derived stem cells,bone marrow-derived stem cells,bone marrowderived mononuclear cells,epidermally-derived mesenchymal stem cells,fibroblast stem cells,keratinocyte stem cells,placental mesenchymal stem cells,and umbilical cord mesenchymal stem cells have all been employed in the treatment of chronic wounds of various etiologies.Most recently,embryonic stem cells have emerged as a novel stem cell therapy with the capacity for multifaceted germ cell layer differentiation.With the capacity for self-renewal and differentiation,stem cells can enrich existing cell populations in chronic wounds in order to overcome barriers impeding the progression of wound healing.Further,stem cell therapies can be utilized to augment cell engraftment,signaling and activity,and resultant patient outcomes.CONCLUSION Assessing observed clinical outcomes,potential for stem cell use,and relevant therapeutic challenges allows wound care stakeholders to make informed decisions regarding optimal treatment approaches for their patients’chronic wounds. | Anjali C Raghuram Roy P Yu Andrea Y Lo Cynthia J Sung Melissa Bircan Holly J Thompson Alex K Wong | 2020 | World Journal of Stem Cells2020，12，7： | 5 |
| 3 | Application of highresolution thermal infrared remote sensing and GIS to assess the urban heat island effect 显示文摘 | Lo C P Quattrovhi D A and Luvall J C | 1997 | International Journal of Remote Sensing1997，18，2： | 2 |
| 4 | Development and applications of the reciprocating plate显示文摘 | Lo P C Baird M H I Rama Rao N V | 1992 | Column Chem Eng Commun1992，116，： | 1 |
| 5 | Ethyl caffeate suppresses NF-kappa B activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin显示文摘 | Chiang Y M Lo C P Chen Y P | 2005 | Br J Pharmacol2005，146，3： | 1 |
| 6 | Urban indicators of China from radiance-calibrated digital DMSP OLS nighttime images显示文摘 | LO C P | 2002 | Annals of the Asso ciation of American Geographers2002，92，： | 1 |
| 7 | Enzymecatalyzed production and chemical composition of diacylglycerols from corn oil deodorizer distillate 显示文摘 | LO S K BAHARIN B S TAN C P | 2004 | Food Biotechnol2004，18，： | 1 |
| 8 | Microwave-hydrothermal decomposition of perfluorooctanoic acid in water by iron-activated persulfate oxidation显示文摘 | Lee Y C Lo S L Chiueh P T | | Water Research0，44，3： | 1 |
| 9 | Smooth sliding mode control for spacecraft attitude tracking maneuvers显示文摘 | Lo S C Chen Y P | 1995 | Journal of Guidance Control and Dynamics1995，18，6： | 1 |
| 10 | Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-13 supeffamily 显示文摘 | LO P C H FRASCH M | 1999 | Mechanisms of Development1999，86，12： | 1 |
| 11 | Blue phosphorescence from iridium (III) complexes at room temperature 显示文摘 | Lo S C Shipley C P Bera R N | 2006 | Chemistry of Materials2006，18，21： | 1 |
| 12 | Ultra-precision Orthogonal Cutting Simulation for Oxygen-free-high-conductivity Copper 显示文摘 | Z C Lin S P Lo | 1997 | Journal of Materials Processing Technology1997，65，13： | 1 |
| 13 | Behavior of mixed multi-walled carbon nanotube/P3HT monolayer at the air/water interface显示文摘 | Lo C L Lee Y L Hsu W P | 2010 | Synth Met2010，160，1920： | 1 |
| 14 | 显示文摘 | Wang H Ho H P Lo K C | 2008 | Mater Chem Phys2008，107，： | 1 |
| 15 | High prevalence of RET proto-oncogene activation (RET/PTC) in papillary thyroid carcinomas 显示文摘 | Lam K Y Lo C Y Leung P S | 2002 | Eur J Endocrinol2002，147，： | 1 |
| 16 | Hetero-arrays of Porphyrins and Phthalocyanines显示文摘 | Lo P C Leng X B Dennis K P N | 2007 | Coord Chem Rev2007，251，1720： | 1 |
| 17 | 显示文摘 | Dendramis G Paleologo C Lo P A | 2014 | Gital Cardiol(Rome)2014，15，3： | 1 |
| 18 | Intrauterine contraceptive device migration to the lower urinary tract: report of 2 cases显示文摘 | Ko P C Lin Y H Lo T S | 2011 | J Minim Invasive Gynecol2011，18，5： | 1 |
| 19 | Chinese female nursing students'coping strategies,self-esteem and related factors in different years ofschool显示文摘 | Ni C P Lo D W Liu X W | 2012 | Journal of Nursing Education and Practice2012，2，4： | 1 |
| 20 | External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreatico-duodenectomy:A prospective randomized trial显示文摘 | Poon R T P Fan S T Lo C M | 2007 | Ann Surg2007，246，3： | 1 |
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