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| 1 | Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma显示文摘Pancreatic cancer(Pa C) shows a clear tendency to increase in the next years and therefore represents an important health and social challenge. Currently, there is an important need to find biomarkers for PaC early detection because the existing ones are not useful for that purpose. Recent studies have indicated that there is a large window of time for PaC early detection, which opens the possibility to find early biomarkers that could greatly improve the dismal prognosis of this tumor. The present manuscript reviews the state of the art of the existing PaC biomarkers. It focuses on the anomalous glycosylation process and its role in PaC. Glycan structures of glycoconjugates such as glycoproteins are modified in tumors and these modifications can be detected in biological fluids of the cancer patients. Several studies have found serum glycoproteins with altered glycan chains in PaC patients, but they have not shown enough specificity for PaC. To find more specific cancer glycoproteins we propose to analyze the glycan moieties of a battery of glycoproteins that have been reported to increase in PaC tissues and that can also be found in serum. The combination of these new candidate glycoproteins with their aberrant glycosylation together with the existing biomarkers could result in a panel, which would expect to give better results as a new tool for early diagnosis of PaC and to monitor the disease. | Esther Llop Pedro E Guerrero AdriàDuran Sílvia Barrabés Anna Massaguer María JoséFerri Maite Albiol-Quer Rafael de Llorens Rosa Peracaula | 2018 | World Journal of Gastroenterology2018，24，24： | 4 |
| 2 | Swine torque teno virus (TTV) infection and excretion dynamics in conventional pig farms显示文摘 | M. Sibila L. Martínez-Guinó E. Huerta A. Llorens M. Mora L. Grau-Roma T. Kekarainen J. Segalés | 2009 | Veterinary Microbiology2009，，3： | 2 |
| 3 | Perceived collective efficacy, subjective well-being, and task performance among electronic work groups: An experimental study 显示文摘 | Salanova M Llorens S Cifre E | 2003 | Small Group Research2003，34，1： | 1 |
| 4 | Does a positive gain spiral of resources,efficacy beliefs and engagement exist显示文摘 | LLORENS S | 2007 | Computers In Human Behavior2007，23，1： | 1 |
| 5 | The von Neumann -Jordan constant, weak orthogonality and normal structure in Banach spaces 显示文摘 | JIMENEZ -MELADO A LLORENS -FUSTER E SAEJUNG S | 2006 | Proc Amer Math Monthly2006，134，2： | 1 |
| 6 | Perceived collective efficacy,subjective well-being and task performance among electronic work groups:An experimental study显示文摘 | Salanova M Llorens S Cifre E Mart′nez I. Schaufeli W.B | | 0，，34： | 1 |
| 7 | Membrane separation technology for the reduction of alcoholic degree of a white model wine显示文摘 | Labanda J Vichi S Llorens J | 2009 | LWT-FoodScience and Technology2009，42，8： | 1 |
| 8 | The dark side of technol- ogies: technostress among users of information and communication technologies 显示文摘 | SALANOVA M LLORENS S CIFRE E | 2013 | International journal of psychology2013，48，3： | 1 |
| 9 | Train A, an RNase A-like protein without RNase activity, is secreted and reabsorbed by the same epididymal cells under testicular control显示文摘 | Castella S Benedetti H de Llorens R | 2004 | Biol Reprod2004，71，： | 1 |
| 10 | Hepatocellular carcinoma in primary biliary cirrhosis: similar incidence to that in hepatitis C virus–related cirrhosis显示文摘 | Lloren? Caballer??a Albert Parés Antoni Castells Angels Ginés Concepció Bru Joan Rodés | 2001 | The American Journal of Gastroenterology2001，，4： | 1 |
| 11 | We need a hero !Toward a Validation of the Healthy and Resilient Organization(HERO) Model显示文摘 | Salanova M Llorens S Cifre E | 2012 | Group & Organization Management2012，37，37： | 1 |
| 12 | Developmental analysis of Lingo-1/ Lernl protein expression in the mouse brain:interaction of its intracellular domain with Myt 11显示文摘 | Llorens F Gil V Iraola S | 2007 | Dev Neurobiol2007，68，4： | 1 |
| 13 | Intervenciones Positivas en Organizaciones Positivas Positive interventions inpositive organizations显示文摘 | Salanova M Llorens S Acosta H | 2013 | Terapia Psicológica2013，31，： | 1 |
| 14 | Diabetes potentiates acetylcholine-induced relaxation in rabbit renal arteries显示文摘 | Alabadi JA Miranda FJ Llorens S | 2001 | European Journal of Pharmacology2001，415，23： | 1 |
| 15 | Does a positive gain spiral of resources, ef- ficacy beliefs and engagement exist显示文摘 | Llorens S | 2007 | Computers in Human Behavior2007，23，1： | 1 |
| 16 | Perceived collective efficacy, subjective well-being and task performance among electronic work groups: an experimental study显示文摘 | Salanova M Llorens S Cifre E | 2003 | Small Groups Research2003，34，1： | 1 |
| 17 | Perceived collective efficiency, subjective well-being and task performance among electronic work groups an experimental study 显示文摘 | Salanova M Llorens S Cifre E | 2003 | Small Group Research2003，34，1： | 1 |
| 18 | Teams make it work:How team work engagement mediates between socialresources and performance in teams显示文摘 | Torrente P Salanova M Llorens S | 2012 | Psicothema2012，24，1： | 1 |
| 19 | Cardiovascular diseases and the nitric oxide pathway显示文摘 | Llorens S Nava E | 2003 | Curr Vasc Pharmacol2003，1，3： | 1 |
| 20 | Swine torque teno virus (TTV) infection and excretion dynamics in conventional pig farms显示文摘 | M. Sibila L. Martínez-Guinó E. Huerta A. Llorens M. Mora L. Grau-Roma T. Kekarainen J. Segalés | 2009 | Veterinary Microbiology2009，，3： | 1 |
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