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| 1 | High-throughput Phenotyping and Genomic Selection:The Frontiers of Crop Breeding Converge显示文摘Genomic selection (GS) and high-throughput phenotyping have recently been captivating the interest of the crop breeding com-munity from both the public and private sectors world-wide.Both approaches promise to revolutionize the prediction of complex traits,including growth,yield and adaptation to stress.Whereas high-throughput phenotyping may help to improve understanding of crop physiology,most powerful techniques for high-throughput field phenotyping are empirical rather than analytical and compa-rable to genomic selection.Despite the fact that the two method-ological approaches represent the extremes of what is understood as the breeding process (phenotype versus genome),they both consider the targeted traits (e.g.grain yield,growth,phenology,plant adaptation to stress) as a black box instead of dissecting them as a set of secondary traits (i.e.physiological) putatively related to the target trait.Both GS and high-throughput phenotyping have in common their empirical approach enabling breeders to use genome profile or phenotype without understanding the underlying biology.This short review discusses the main aspects of both approaches and focuses on the case of genomic selection of maize flowering traits and near-infrared spectroscopy (NIRS) and plant spectral reflectance as high-throughput field phenotyping methods for complex traits such as crop growth and yield. | Lloren Cabrera-Bosquet Jos Crossa Jarislav von Zitzewitz María Dolors Serret Jos Luis Araus | 2012 | Journal of Integrative Plant Biology2012，54，5： | 11 |
| 2 | Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma显示文摘Pancreatic cancer(Pa C) shows a clear tendency to increase in the next years and therefore represents an important health and social challenge. Currently, there is an important need to find biomarkers for PaC early detection because the existing ones are not useful for that purpose. Recent studies have indicated that there is a large window of time for PaC early detection, which opens the possibility to find early biomarkers that could greatly improve the dismal prognosis of this tumor. The present manuscript reviews the state of the art of the existing PaC biomarkers. It focuses on the anomalous glycosylation process and its role in PaC. Glycan structures of glycoconjugates such as glycoproteins are modified in tumors and these modifications can be detected in biological fluids of the cancer patients. Several studies have found serum glycoproteins with altered glycan chains in PaC patients, but they have not shown enough specificity for PaC. To find more specific cancer glycoproteins we propose to analyze the glycan moieties of a battery of glycoproteins that have been reported to increase in PaC tissues and that can also be found in serum. The combination of these new candidate glycoproteins with their aberrant glycosylation together with the existing biomarkers could result in a panel, which would expect to give better results as a new tool for early diagnosis of PaC and to monitor the disease. | Esther Llop Pedro E Guerrero AdriàDuran Sílvia Barrabés Anna Massaguer María JoséFerri Maite Albiol-Quer Rafael de Llorens Rosa Peracaula | 2018 | World Journal of Gastroenterology2018，24，24： | 4 |
| 3 | Critical study of andimprovements in chromatographic methods for the analysis of type B trichotheeenes显示文摘 | Mateo J J Llorens A Mateo R | 2001 | Journal of Chromatography A2001，918，1： | 1 |
| 4 | A review of rain- fall intereeption modelling 显示文摘 | Muzylo A Llorens P Valente F | 2009 | Journal of Hydrology2009，370，1： | 1 |
| 5 | Elemental fin- gerprint of wines from the protected designation of origin va- lencia 显示文摘 | Gonzalvez A Llorens A Cervera M L | 2009 | Food Chemistry2009，112，1： | 1 |
| 6 | The von Neumann -Jordan constant, weak orthogonality and normal structure in Banach spaces 显示文摘 | JIMENEZ -MELADO A LLORENS -FUSTER E SAEJUNG S | 2006 | Proc Amer Math Monthly2006，134，2： | 1 |
| 7 | Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression显示文摘 | Rodrigo I Lopez-Barcons L | 1998 | Lab Invest1998，78，9： | 1 |
| 8 | Sludge dewatering and stabilization in drying reed beds:characterization of three full-scale systems in Catalonia,Spain显示文摘 | Uggetti E Llorens E Pedescoll A | 2009 | Bioresource Technology2009，100，17： | 1 |
| 9 | Environment - flexibility coalignment and performance: an analysis in large versus small firms 显示文摘 | Verdu - Jover A J Llorens - Montes F J J Garcia - Morales V | 2006 | Journal of Small Business Management2006，44，3： | 1 |
| 10 | Wool scouring waste treatment by a combination of coagulation-flocculation process and membrane separation technology 显示文摘 | LABAB J LLORENS A J | 2008 | Chemical Engineering and Processing2008，47，7： | 1 |
| 11 | Comparison of extraction and clean-up proc-edures for analysis of zearalenone in corn, rice and wheat grains by high- perform-ance liquid chromatography with photodiode array and fluorescence detection显示文摘 | Llorens A Mateo R Mateo J J | 2002 | Food Addit Con- tain2002，19，3： | 1 |
| 12 | Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression显示文摘 | Llorens A Rodrigo I Lopez-Barcons L | 1998 | Lab Invest1998，78，9： | 1 |
| 13 | On the comparison of reliability experiments based on the convolution order 显示文摘 | Shaked M Suarez - Llorens A | 2003 | Journal of the American Statistical Association2003，98，69： | 1 |
| 14 | Phytotoxicity and Heavy Metals Speciation of Stabilized Sewage Sludge显示文摘 | Fuentes A Llorens M Saez J | 2004 | J Hazard Mater2004，108，3： | 1 |
| 15 | Proinflammatory Cytokines and C-Reactive Protein in Uveitis Associated with Beh?et’s Disease显示文摘 | Marina Mesquida Blanca Molins Victor Lloren? Maite Sainz de la Maza María Victoria Hernandez Gerard Espinosa Alfredo Adán Francisco J. Ascaso | 2014 | Mediators of Inflammation2014，，： | 1 |
| 16 | Relationships of gag-pol diversity between Ty3/CoTsy and Retroviridae LTR retroelements and the three kings hypothesis显示文摘 | Llorens C Fares M A Moya A | 2008 | BMC evolutionary biology2008，8，1： | 1 |
| 17 | Separation of metal ions, and chelating agents by nanofiltration显示文摘 | T Balany/a J Labanda J Llorens J | 2009 | Journal of Membrane Science2009，345，： | 1 |
| 18 | Metallic-based micro and nanocomposites in food contact materials and active food packaging显示文摘 | Llorens A Lloret E Picouet P A | 2012 | Trends in Food Science & Technology2012，24，1： | 1 |
| 19 | Elemental Fin-gerprint of Wines from the Protected Designation of OriginValencia显示文摘 | GonzalvezA Llorens A Cervera M L | 2009 | Food Chemistry2009，112，1： | 1 |
| 20 | Major colocalization of the extracellularmatrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils显示文摘 | Mollinedo F Nakajima M Llorens A | 1997 | Biochem J1997，327，： | 1 |
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