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| 1 | 六味安消胶囊治疗功能性消化不良的多中心随机对照临床研究显示文摘目的 评估六味安消胶囊(邦消安)治疗功能性消化不良(FD)的疗效、安全性以及耐受性,并与莫沙比利比较.方法 采用多中心、随机、开放、平行、阳性药物对照方法进行研究.入选99例符合罗马Ⅱ标准的FD患者,分为2组,试验组50例,对照组49例,试验为期4周,包括1周基线期,2周试验组六味安消(3次/d,3粒/次,餐后服用)或对照组莫沙比利(3次/d,5 mg/次,餐前15~30 min服用)治疗期及治疗结束1周随访期.评估标准:对患者全部FD症状进行总体评估,对患者每个FD参数的改善程度以及安全性进行评估.结果 治疗前试验组与对照组间人口统计学特征、体格检查和疾病特征差异均无统计学意义(P>0.05).治疗期2周和随访期1周,试验组与对照组间症状总积分及5 h胃排空率比较,差异均无统计学意义(P>0.05);试验组及对照组治疗后14 d与随访后28 d症状总积分自身前后比较,差异均有统计学意义(P<0.05);生活质量评价在日常活动方面两组间差异有统计学意义(P<0.05),其他各项指标试验组亦较对照组下降,但差异均无统计学意义.安全性分析结果示,两组间不良事件、不良反应等指标的差异均无统计学意义(P>0.05).结论 六味安消能有效治疗FD各症状,疗效稳定,并具有良好的安全性和耐受性. | Liuwei′anxiao Clinical Research Group. | 2006 | 中华消化杂志2006，26，1： | 23 |
| 2 | Viola baoshanensis,a plant that hyperaccumulates cadmium显示文摘This paper reports upon the finding of Viola baoshanensis, a cadmium (Cd) hyperaccumulator through field survey and greenhouse experiments. Average Cd concentration in the shoots and roots of V. baoshanensis growing on Baoshan lead/zinc mine in Hunan Province, China, was 1168 and 981 mg/kg, respectively, varying from 456 to 2310mg/kg in the shoots, and from 233 to 1846 mg/kg in the roots.The ratio of Cd concentration in shoot to root (DW) and that in plant shoots to total concentration in surface soil was 1.32 and 2.38, respectively. Under nutrient solution culture, biomass (DW) of V. baoshanensis exposed to 0-30 mg/L Cd insolution increased with Cd supply increasing and reached a maximum at 30 mg/L Cd. Further increase of Cd concentration (40, 50 mg/L) in solution significantly reduced biomass.Cd concentration in the shoots was positively correlated with Cd concentration in the culture medium. Cd concentration in the shoots reached 4825 mg/kg at 50 mg/L Cd solution. Theratio of Cd concentration of shoots to roots in V. baoshanensis was greater than 1 at all Cd treatments, with an average of 1.67 (1.14-2.22). The results indicate that V. baoshanensis is a Cd hyperaccumulator plant. | LIUWei SHUWensheng LANChongyu | 2004 | Chinese Science Bulletin2004，49，1： | 21 |
| 3 | Detection of nanobacteria in serum, bile and gallbladder mucosa of patients with cholecystolithiasis显示文摘In 1990, nanobacterium was found and named by Kajander.1 With distinct mineralizing ability, nanobacteria are thought to play a role in extraskeletal calcifying diseases. It have been found in many human tissues, but whether they exist in the bile or gallbladder mucosa remains unclear. The present study was undertaken to investigate by ELISA, bacterial culturing, immunohistochemical staining and transmission electron microscopy (TEM), whether nanobacteria exist in serum, bile or gallbladder mucosa of healthy people and patients with cholecystolithiasis. | WENYu LIYong-guo YANGZhu-lin WANGXue-jun WEIHong LIUWei MIAOXiong-ying WANGQun-wei HUANGSheng-fu YANGJing E.OlaviKajander NevaCiftcioglu | 2005 | Chinese Medical Journal2005，，5： | 15 |
| 4 | The effect of Helicobacter pylori infection on expression of macrophage migration inhibitory factor by T cells and macrophages in gastric mucosa显示文摘Background Macrophage migration inhibitory factor (MIF) plays a pivotal role in inflammatory and immune-mediated diseases. However, its molecular function and role in gastrointestinal diseases has rarely been studied and thus warrants an in-depth investigation. This study was designed and conducted to determine MIF expression in Helicobacter pylori (H. pylori)-induced gastritis and the effect of H. pylori on MIF expression in monocytes in vitro. Methods Gastric specimens of 62 patients with chronic gastritis were obtained through endoscopic biopsies. Both gastric antrum and body were examined for histopathologic changes. Positive H. pylori was determined through rapid urease test and histopathological examination. A patient was classified as H. pylori positive if both tests showed positive results. The updated Sydney System was employed to assess the severity and activity of gastric inflammation. Double immunoassaying for MIF/T-cells (CD45RO) and MIF/macrophage (KP1), as well as in situ hybridization for the expression of MIF mRNA were used for the current analysis. THP-1, a monocyte cell line, was co-incubated with H. pylori strains (ATCC26695) and subsequently examined for the expression of MIF protein and mRNA by enzyme linked immunosorbent assay and retrospective transcription-polymerase chain reaction, respectively. Results Among 62 patients with chronic gastritis, significant increase in total T-cells, MIF^+ T-cells, total macrophages, MIF^+ macrophages and MIF mRNA^+ cells was observed in 42 H. pylori positive patients compared to H. pylori negative patients. Moreover, the increase of the MIF mRNA^+ cells was highly correlated with the severity of the disease(number of MIF mRNA^+cells/mm^2, mild: 2834±382, moderate: 3569±123, severe: 3881±118, P<0.01). In vitro results showed that the expression of MIF protein and mRNA in monocytes was significantly increased after incubation with H. pylori strains.Conclusions Overexpression of MIF is common in H. pylori-induced gastric inflammation, which suggests MIF may play an important role in the initiation and development of this disease. | HEXing-xiang YANGJun ZHENGXue-ling DINGYuan-wei SHENQing-yan LIUWei ZHAOYing-heng | 2005 | Chinese Medical Journal2005，，14： | 11 |
| 5 | SIMULTANEOUS SHAPE AND TOPOLOGY OPTIMIZATION OF TRUSS UNDER LOCAL AND GLOBAL STABILITY CONSTRAINTS显示文摘A new approach for the solution of truss shape and topology optimization problem sunder local and global stability constraints is proposed. By employing the cross sectional areas of each bar and some shape parameters as topology design variables, the difficulty arising from the jumping of buckling length phenomenon can be easily overcome without the necessity of introducing the overlapping bars into the initial ground structure. Therefore computational efforts can be saved for the solution of this kind of problem. By modifying the elements of the stiffness matrix using Sigmoid function, the continuity of the objective and constraint functions with respect to shape design parameters can be restored to some extent. Some numerical examples demonstrate the effectiveness of the proposed method. | GuoXu LiuWei LiHongyan | 2003 | Acta Mechanica Solida Sinica2003，16，2： | 5 |
| 6 | Effect of pre-homogenizing treatment on microstructure and mechanical properties of hot-rolled AZ91 magnesium alloys显示文摘To improve the homogeneity and rolling formability of as-cast AZ91 magnesium,the effects of pre-homogenizing treatment on microstructure evolution,deformation mechanism,mechanical properties and tensile fracture morphology of hot-rolled AZ91 magnesium alloy were studied.The results showed that the amount of coarseβ-Mg17Al12 phase decreases dramatically,being distributed along the grain boundaries as small strips after homogenizing.Twining plays a dominant role in the deformation mechanism of AZ91 alloys in the experimental condition,while dynamic recrystallization(DRX)considerably occurred in homogenized-rolled alloys,contributed to microstructure uniformity andβ-Mg17Al12 phase precipitated refinement.The tensile strength of homogenized-rolled AZ91 alloys increases dramatically with elongation declining slightly in contrast to homogenized alloys.The fracture surface of homogenized-rolled specimen exhibits more ductile fracture with the manifestation of a large amount of dimples distributing higher density in matrix,while the micro cracks are prone to initiate around the Mg/Mg17Al12 phase interface and grain boundaries owing to the fragile interface bonding of two phases. | Liuwei Zheng Huihui Nie Wei Liang Hongxia Wang Yide Wang | 2016 | Journal of Magnesium and Alloys2016，4，2： | 5 |
| 7 | The Kuroshio Transport East of Taiwan and the Sea Surface Height Anomaly from the Interior Ocean显示文摘The relationship between the Kuroshio transport to the east of Taiwan and the SSHA (Sea Surface Height Anomaly) field is studied based on the World Ocean Circulation Experiment (WOCE) PCM-1 moored current meter array observation, the satellite altimeter data from the MSLA (Map of Sea Level Anomaly) products merged with the ERS and TOPEX/POSEIDON (T/P) data sets, and the WOCE satellite-tracked drifting buoy data. It is confirmed that the Kuroshio transport across PCM-1 array highly correlates with the SSHA upstream (22°-24°N, 121.75°-124°E). The SSHA is not locally generated by the developed Kuroshio meandering but is from the interior ocean and is propagating westward or northwestward. During the period from October 1992 to January 1998, two events of the northwestward propagating negative SSHA occurred, during which the SSHA merged into the Kuroshio and caused the remarkable low transport events in contrast to the normal westward propagating negative SSHA. It is also shown that the lower Kuroshio transport event would be generated in different ways. The negative anomaly in the upstream of PCM-1 array can reduce the Kuroshio transport by either offshore or onshore Kuroshio meandering. The positive anomaly, which is strong enough to detour the Kuroshio, can cause an offshore meandering and a low transport event at the PCM-1 array. | LIUWei LIUQinyu JIAYinglai | 2004 | Journal of Ocean University of China2004，3，2： | 4 |
| 8 | Synthesis and Liquid Crystal Properties of Transition Metal Complexes of Meso-tetra(4-n-myristyloxyphenyl)porphyrin显示文摘Transition metal complexes of meso-tetra(4-myristyloxyphenyl)porphyrin TMPPM [M =Mn, Fe, Co, Ni, Cu, Zn; TMPP=mesotetra(4-myristyloxyphenyl)porphyrin] have been synthesized and characterized by means of elemental analyses, UV-Vis spectra, infrared photoacoustic spectra, 1H NMR spectra, molar conductance and differential scanning calorimetry(DSC). The ligand and the Zn complex show liquid crystalline behavior. According to the DSC thermogram of the Zn complex, it exhibits a lower phase transition temperature -7.453 ℃ and a wide mesophase temperature span, 77 ℃. | LIUWei SHIYu-hua SHITong-shun | 2004 | Chemical Research in Chinese Universities2004，20，1： | 3 |
| 9 | Aerosol optical properties under different pollution levels in the Pearl River Delta(PRD) region of China显示文摘To clarify the aerosol hygroscopic growth and optical properties of the Pearl River Delta(PRD)region,integrated observations were conducted in Heshan City of Guangdong Province from October 19 to November 17,2014.The concentrations and chemical compositions of PM2.5,aerosol optical properties and meteorological parameters were measured.The mean value of PM2.5 increased from less than 35(excellent)to 35-75μg/m^3(good)and then to greater than 75μg/m^3(pollution),corresponding to mean PM2.5 values of 24.9,51.2,and 93.3μg/m^3,respectively.The aerosol scattering hygroscopic growth factor(f(RH=80%))values were 2.0,2.12,and 2.18 for the excellent,good,and pollution levels,respectively.The atmospheric extinction coefficient(σext)and the absorption coefficient of aerosols(σap)increased,and the single scattering albedo(SSA)decreased from the excellent to the pollution levels.For different air mass sources,under excellent and good levels,the land air mass from northern Heshan had lower f(RH)andσsp values.In addition,the mixed aerosol from the sea and coastal cities had lower f(RH)and showed that the local sources of coastal cities have higher scattering characteristics in pollution periods. | Liuwei Kong Min Hu Qinwen Tan Miao Feng Yu Qu Junling An Yuanhang Zhang Xingang Liu Nianliang Cheng | 2020 | Journal of Environmental Sciences2020，32，1： | 3 |
| 10 | Polymorphism of the second exon of human leukocyte antigen-DQA1, -DQB1 gene and genetic susceptibility to idiopathic dilated cardiomyopathy in people of the Han nationality in northern China显示文摘Idiopathic dilated cardiomyopathy (IDC) is characterized by dilation and impaired contraction of the left ventricle or both, and it is a relevant cause of heart failure and a common indication for heart transplantation. The major pathogenetic hypothesis in IDC involves autoimmune mediated damage to myocytes. The development of autoimmune inflammatory damage occurs only in patients with a predisposing genetic background. Changes in the immune system concerning cell-mediated and humoral immunity have been detected. The immune system is strictly related to human leukocyte antigen (HLA), which is located on the surface of antigen presenting cells. Its primary function is to restrict T-cell receptors in the process of recognizing auto- or exterior antigen, and thus participates in or mediates immunological recognition, immunological response and immune regulation at various levels. HLA is a genetic marker of susceptibility to autoimmune myocardial damage.1 In the present study, the HLA-DQA1 and -DQB1 alleles in IDC patients were detected with the techniques of polymerase chain reaction-sequence specific primers (PCR-SSP) to explore the immunogenetic mechanisms involved in the pathogenesis of IDC. | LIUWei LIWei-min SUNNing-ling | 2005 | Chinese Medical Journal2005，，3： | 2 |
| 11 | 显示文摘 | LIHui(李惠) PEIHui-lian(裴会莲) LIUWei(刘巍) | 2007 | 药物分析杂志2007，27，： | 1 |
| 12 | 显示文摘 | WENBing-gong FENGWu-fa LIUWei etal(闻兵工 冯伍法 刘伟 等) | 2009 | 测绘科学技术学报2009，26，2： | 1 |
| 13 | Influence of Interactions on Populations for Hyperons in Neutron Stars显示文摘The numerical results of the populations for the baryon octet in neutron star matter have been presented by solving a set transcendental equations in the framework of the relativistic mean field approximation. The influence of the hyperon interactions on hyperon populations in neutron star matter is discussed. The results manifest that when the ratio of the hyperon-to-nucleon couplings increases, all hyperons appear towards low baryon density direction. | LIUGuang-Zhou ZHAOEn-Guang LIUWei SUNBao-Xi | 2004 | Communications in Theoretical Physics2004，41，2： | 1 |
| 14 | Deformation and energy absorption ofaluminum foam-filled tubes subjected to oblique loading显示文摘 | Zhibin Li Jilin Yu Liuwei Guo | 2012 | InternationalJournal of Mechanical Sciences2012，，54： | 1 |
| 15 | Evaluationofvarinuseategories of turbulence models for predicting air distribution in an airliner cabin显示文摘 | LiuWei WenJizhou LinC etal | 2013 | Building and Environment2013，65，7： | 1 |
| 16 | TheeffectofPanaxquinquefoliumonlipidmetabo-lismlevelinratsofinsulinresistance显示文摘 | GEPengling(葛鹏玲) LIJi(李冀) LIUWei(刘微) etal | | 中医药学报0，，： | 1 |
| 17 | Power supply for the superconducting TF magnet system of EAST显示文摘 | Liu Xiaoning Jiang Jiafu Xu Liuwei | 2006 | Nuclear Fusion2006，46，： | 1 |
| 18 | The 'von Karman vortex street' to the west of Big Island显示文摘Satellite-tracked drifting buoy data and altimetry data are used to study the active vortex field to the west of Big Island. A pair of vortexes were observed at the trajectory of buoy in 1995. The westward propagation of the vortex pair is studied in detail by reproducing the loops of each vortex. The orbital period and radius of the pair of vortex are determined to be 10-11 d and 58-68 km. Two arrays of contra-rotating vortices are displayed in the average sea surface height anomaly (SSHA) field to the west of Big Island. Based on the calculation of the fluid dynamical parameter, the “von Karman vortex street” is proved to be generated to the west of Big Island as the North Equatorial Current impinges upon Big Island from the east. Finally, the analysis of the buoy trajectories in a decade contributes to the conclusion of the pattern of VKVS in a statistical view. | LIUWei LIUQinyu | 2004 | Acta Oceanologica Sinica2004，23，3： | 1 |
| 19 | Deformation and energy ab- sorption of aluminum foam-filled tubes subjected to oblique loading 显示文摘 | Li Zhibin Yu Jilin Guo Liuwei | 2012 | International Journal of Mechanical Sciences2012，，54： | 1 |
| 20 | 显示文摘 | WANGYou-He(王有和) LIXiang(李翔) LIUWei(刘伟) etal | | Guisuanyan Tongbao0，，： | 1 |
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