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| 1 | Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the human fetal epidermis显示文摘 | Zhou JX Jia LW Liu WM Miao CL Liu S Cao YJ Duan EK | 2006 | 中国生物学文摘2006，20，5： | 8 |
| 2 | Expression of matrix metallo-proteinase-28 in human normal cytotrophoblast cells and a choriocarcinoma cell line,JEG-3显示文摘There are striking similiarities present between the behavior of invasive placentaL cells and that of invasive cancer cells. Matrix metalloproteinases (MMPs) are one of the most important mediators. MMP-28, the new member of MMPs, was sequenced and identified recently. Expression of MMP-28 mRNA and protein in the cytotrophoblast cells and a choriocarcinoma cell line, JEG-3 cell, was conducted by zymography, RT-PCR and Northern blot. There is MMP-28 mRNA expression in both the cytotrophoblast cells and JEG-3 cells by RT-PCR. The activity of MMP-28 in cytotrophoblast cells was significantly weaker than that in JEG-3 (P < 0.01) by zymography. Furthermore, mRNA expression of MMP-28 was significantly stronger (P < 0.001) in JEG-3 than in human cytotrophoblast cells in a time-dependent way by Northern Blot. Our results suggest that MMP-28 may play a role in some of the tissue-remodeling events associated with normal pregnancy and tumor progression. | Zhang, J Cao, YJ Liu, WM Zhao, BS Zeng, GQ Duan, EK | 2002 | Chinese Science Bulletin2002，47，9： | 4 |
| 3 | Mitochondrial neuronal uncoupling proteins:a target for potential disease-modification in Parkinson’s disease Philip显示文摘This review gives a brief insight into the role of mitochondrial dysfunction and oxidative stress in the converging pathogenic processes involved in Parkinson’s disease(PD).Mitochondria provide cellular energy in the form of ATP via oxidative phosphorylation,but as an integral part of this process,superoxides and other reactive oxygen species are also produced.Excessive free radical production contributes to oxidative stress.Cells have evolved to handle such stress via various endogenous anti-oxidant proteins.One such family of proteins is the mitochondrial uncoupling proteins(UCPs),which are anion carriers located in the mitochondrial inner membrane.There are five known homologues(UCP1 to 5),of which UCP4 and 5 are predominantly expressed in neural cells.In a series of previous publications,we have shown how these neuronal UCPs respond to 1-methyl-4-phenylpyridinium(MPP+;toxic metabolite of MPTP)and dopamine-induced toxicity to alleviate neuronal cell death by preserving ATP levels and mitochondrial membrane potential,and reducing oxidative stress.We also showed how their expression can be influenced by nuclear factor kappa-B(NF-B)signaling pathway specifically in UCP4.Furthermore,we previously reported an interesting link between PD and metabolic processes through the protective effects of leptin(hormone produced by adipocytes)acting via UCP2 against MPP+-induced toxicity.There is increasing evidence that these endogenous neuronal UCPs can play a vital role to protect neurons against various pathogenic stresses including those associated with PD.Their expression,which can be induced,may well be a potential therapeutic target for various drugs to alleviate the harmful effects of pathogenic processes in PD and hence modify the progression of this disease. | WL Ho Jessica WM Ho Hui-Fang Liu Danny HF So Zero HM Tse Koon-Ho Chan David B Ramsden Shu-Leong Ho | 2012 | Translational Neurodegeneration2012，1，1： | 3 |
| 4 | Combing the utrine depletion procedure and myomectomy may be useful for treating symptomatic fibroids 显示文摘 | Liu WM Tzeng CR Yi-Jen C | 2004 | Fertil Steril2004，82，1： | 1 |
| 5 | Laparoscopic bipolar coagulation of uterine vessels:a new method for treating symptomatic fibroids显示文摘 | Liu WM Ng HT Wu YE | 2001 | Fertil Steril2001，75，2： | 1 |
| 6 | Laparoscopic bipolar co- agulation of uterine vessels: a new method for treating symptomatic fibroids 显示文摘 | Liu WM Ng HT Wu YC | 2001 | Fertil Steril2001，75，2： | 1 |
| 7 | Combined photodynamic therapy and intravitreal triamcinolone for choroi- dal neovascularization secondary to punctuate inner choroi-dop- athy or of idiopathic origin:one-year results of a prospective se- ries显示文摘 | Chan WM Lai TY Lau TT Lee VY Liu DT Lam DS | 2008 | Retina2008，28，1： | 1 |
| 8 | The miR-200 family regu- lates the epithelial-mesenchymal transition induced by EGF/ EGFR in anaplastic thyroid cancer eells显示文摘 | Zhang Z Liu ZB Ren WM | 2012 | Int J Mol Med2012，30，4： | 1 |
| 9 | Comparison of surgery alone andcombined surgical -medical treatment in the management of symp-tomatic uterine adenomyoma显示文摘 | Wang PH Liu WM Fuh JL | 2009 | Fertil Steril2009，92，3： | 1 |
| 10 | Effect of Previous Live Birth and Prior Route of Delivery on the Outcome of Early Medical Abortion显示文摘 | Chien LW Liu WM Tzeng CR | 2009 | Obstet Gynecol2009，113，3： | 1 |
| 11 | Establishment of an ELISA system for determining soluble LAIR-1 levels in sera of patients with HFRS and kidney transplant 显示文摘 | Ouyang WM Xue JN Liu JM | 2004 | J Immunol Methods2004，292，12： | 1 |
| 12 | Enrichment and identification of human'fetal' epidermal stem cells显示文摘 | Zhou JX Chen SY Liu WM | 2004 | Hum Reprod2004，9，： | 1 |
| 13 | Photo- dynamic therapy with verteportin for sub- foveal choroidal neovascularisation of pa- thologic myopia in Chinese eyes: a pros- pective series of 1 and 2 year follow up显示文摘 | Lain DS Chan WM Liu DT | 2004 | Br J Ophthalmol2004，88，10： | 1 |
| 14 | Effects of atorvastatin on the Th1/Th2 polarization of ongoing experimental autoimmune myocarditis in Lewis rats 显示文摘 | Liu W Li WM Gao C | 2005 | J Autoimmun2005，25，4： | 1 |
| 15 | Discuss the reasons of the recur after the thoracic wall tuberculosis surgery显示文摘 | ZHANG WM WANG Fc | 2005 | Journal of Chinese Antituberculosis Associatioo2005，27，4： | 1 |
| 16 | Prevalence of dry eye among an elderly Chinese population in Taiwan:the Shihpai Eye Study显示文摘 | Lin PY Tsai SY Cheng CY Liu JH Chou P Hsu WM | 2003 | Ophthalmology2003，110，6： | 1 |
| 17 | Protective effects of N-acetylcysteine in iso-proterenol-induced myocardium injury in rats显示文摘 | Liu B Li WM Li Y | 2009 | Mol Biol Rep2009，36，4： | 1 |
| 18 | Comblining the uterine depletion procedure and myomectomy may be useful for treating symptomatic fibroids显示文摘 | Liu WM Tzeng CR Yi-Jen C | 2004 | Fertil Steril2004，82，1： | 1 |
| 19 | Aqueous humor levels of vascular endothelial growth factor and pigment epithelium- derived factor in polypoidal choroidal vasculopathy and choroidal neovascularization显示文摘 | Tong J P Chan WM Liu DT | 2006 | Am J Ophthalmol2006，141，3： | 1 |
| 20 | Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study 显示文摘 | Lin PY Tsai SY Cheng CY Liu JH Chou P Hsu WM | 2003 | Ophtlwlrrwlogy2003，110，6： | 1 |
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