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| 1 | A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘 | King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse | 2017 | Journal of Geriatric Cardiology2017，14，12： | 5 |
| 2 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 3 | A permutation-based dual genetic algorithm for dynamic optimization problems显示文摘 | Liu L L Wang D W Ip W H | 2008 | Soft Computing2008，13，7： | 1 |
| 4 | Thermogenic effects of sibutramine and its metabolites显示文摘 | Connoley IP Liu YL Frost I | 1999 | Br J Pharmacol1999，126，6： | 1 |
| 5 | Structure and photoluminescence of ZnSe nanoribbons grown by metal organic chemical vapor deposition 显示文摘 | Zhang X T Ip K M Liu Z | 2004 | Appl Phys Lett2004，84，： | 1 |
| 6 | Gene-environment interac- tion between interleukin-4 promoter and molds in childhood asthma显示文摘 | Hwang BF Liu IP Huang TP | 2012 | Ann Epidemiol2012，22，： | 1 |
| 7 | Myosin Vlla par- ticipate in opsin transport through the photoreceptor cihum 显示文摘 | Liu X Udovichenko IP Brown SD | 1999 | J Neurosci1999，19，15： | 1 |
| 8 | Chemotherapy alone versus surgery followed by chemotherapy for stage I/IIE large-cell lymphoma of the stomach显示文摘 | Liu HT Hsu C Chiang IP | 2000 | Am J Hematol2000，64，： | 1 |
| 9 | Effects of the Cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in lep(ob)/lep(ob) mice显示文摘 | Liu YL Connoley IP Wilson CA | 2005 | Int J Obes(Lond)2005，29，2： | 1 |
| 10 | E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours显示文摘 | Chen CL Liu SS Ip SM | 2002 | Eur J Cancer2002，39，4： | 1 |
| 11 | Effects of the canna binoid CB1 receptor antagonist SR141716 on oxygen consump- tion and soleus muscle glucose uptake in Lep (ob) /Lep (ob) mice 显示文摘 | Liu YL Connoley IP Wilson CA | 2005 | IntJ Obes (Lond)2005，29，2： | 1 |
| 12 | Genetic local search for resourceconstrained project scheduling under uncertainty显示文摘 | LIU S X YUNG K L IP W H | 2007 | International Journal of Information and Management Sciences2007，18，4： | 1 |
| 13 | Effects of the Cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in lep(ob)/lep(ob) mice显示文摘 | Liu YL Connoley IP Wilson CA | 2005 | Int J Obes(Lond)2005，29，2： | 1 |
| 14 | Interleukin-6 in rheumatoid arthritis-from the laboratory to the bedside显示文摘 | Liu X Teichtahl AJ Wicks IP | 2015 | Curr Pham Des2015，21，17： | 1 |
| 15 | E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours显示文摘 | Chen CL Liu SS Ip SM | 2003 | Eur J Cancer2003，39，4： | 1 |
| 16 | Disruption of estrogen receptor α-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy显示文摘 | Wensheng Liu Margot M. Ip Matthew B. Podgorsak Gokul M. Das | 2009 | Breast Cancer Research and Treatment2009，，1： | 1 |
| 17 | E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours显示文摘 | Chen CL Liu SS Ip SM | | 0，，： | 1 |
| 18 | Thermogenic effects of sibutramine and its metabolites 显示文摘 | Connoley IP Liu YL Frost L | 1999 | Br J Pharmacol1999，126，6： | 1 |
| 19 | Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice显示文摘 | Liu YL Connoley IP Wilson CA Stock MJ | 2005 | Int J Obes (Lond)2005，29，： | 1 |
| 20 | E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumors 显示文摘 | Chen CL Liu SS Ip SM | 2003 | Eur JCancer2003，39，4： | 1 |
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