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| 1 | Risk Factors of Onset of Asthma, A 12-year Prospective Follow-up Study 显示文摘 | Porsbjerg C Von Linstow M L Ulrik C S | 2006 | Chest2006，129，2： | 1 |
| 2 | Risk factors for onset of asthma a 12-year prospective follow-up study 显示文摘 | Porsbjerg C yon Linstow ML Ulrik CS | 2006 | Chest2006，129，2： | 1 |
| 3 | Risk factors for onset of asthma, a 12 - year prospective follow-up study 显示文摘 | Porsbjerg C Linstow ML Ulrik CS | 2006 | Chest2006，129，： | 1 |
| 4 | No spatial working memory defi- cit in beta- amyloid -exposed rats显示文摘 | Van Linstow RE Platt B Riedel G | 2002 | Neuropsychopharmacol Biol Psychiatry2002，26，5： | 1 |
| 5 | Biochemical dysfunction and memory loss: the case of Alzheimer's dementia显示文摘 | von Linstow Roloffe Platt B | 1999 | Cell Mol Life Sci1999，55，： | 1 |
| 6 | Long - term study of chronic oral aluminum exposure and spatial working memory in rats显示文摘 | Linstow Roloff E Platt B Riedel G | 2002 | Behav Neurosci2002，116，2： | 1 |
| 7 | Clinical and epidemiologic characteristics of human bocavirus in Danish infants: results from a prospective birth cohort study 显示文摘 | von Linstow ML Hogh M Hcgh B | 2008 | Pediatr Infect Dis J2008，27，： | 1 |
| 8 | Risk factors foronset of asthma a 12-year prospective follow-up study显示文摘 | Porsbjerg C von Linstow ML Ulrik CS | 2006 | Chest2006，129，2： | 1 |
| 9 | Risk factors for onset of asthma,a 12-year prospective follow-up study显示文摘 | Porsbjerg C Linstow ML Ulrik CS Christensen SN Bacher V | 2006 | Chest2006，129，2： | 1 |
| 10 | Risk factors for onset of asthma: A 12 - year prospective follow - up study 显示文摘 | Porsbjerg C yon Linstow ML Utrik CS | 2006 | Chest2006，129，2： | 1 |
| 11 | Excretion patterns of human metapneumovirus and respiratory syncytial virus among young children显示文摘 | Von Linstow ML Eugen-Olsen J Koch A | | 0，，08： | 1 |
| 12 | Clinical and epidemiologic characteristics of human Bocavirus in Danish infants:results from a prospective birth cohort study显示文摘 | von Linstow ML Hogh M Hogh B | 2008 | Pediatr Infect Dis J2008，27，10： | 1 |
| 13 | Prevention of mother-to-child transmission of HIV in Denmark,1994-2008显示文摘 | von Linstow ML Rosenfeldt V Lebech AM | 2010 | HIV Med2010，11，7： | 1 |
| 14 | Physical train- ing May enhance beta-cell function in type 2 diabetes显示文摘 | Dela F von Linstow ME Mikines KJ | 2004 | AmJ Physiol Endocrinol Metab2004，287，5： | 1 |
| 15 | Precision medicine in Parkinson's disease patients with LRRK2 and GBA risk variants-Let's get even more personal显示文摘Parkinson's disease(PD)is characterized by motor deficits and a wide variety of non-motor symptoms.The age of onset,rate of disease progression and the precise profile of motor and non-motor symptoms display considerable individual variation.Neuropathologically,the loss of substantia nigra dopaminergic neurons is a key feature of PD.The vast majority of PD patients exhibit alpha-synuclein aggregates in several brain regions,but there is also great variability in the neuropathology between individuals.While the dopamine replacement therapies can reduce motor symptoms,current therapies do not modify the disease progression.Numerous clinical trials using a wide variety of approaches have failed to achieve disease modification.It has been suggested that the heterogeneity of PD is a major contributing factor to the failure of disease modification trials,and that it is unlikely that a single treatment will be effective in all patients.Precision medicine,using drugs designed to target the pathophysiology in a manner that is specific to each individual with PD,has been suggested as a way forward.PD patients can be stratified according to whether they carry one of the risk variants associated with elevated PD risk.In this review we assess current clinical trials targeting two enzymes,leucine-rich repeat kinase 2(LRRK2)and glucocerebrosidase(GBA),which are encoded by two most common PD risk genes.Because the details of the pathogenic processes coupled to the different LRRK2 and GBA risk variants are not fully understood,we ask if these precision medicinebased intervention strategies will prove'precise'or'personalized'enough to modify the disease process in PD patients.We also consider at what phases of the disease that such strategies might be effective,in light of the genes being primarily associated with the risk of developing disease in the first place,and less clearly linked to the rate of disease progression.Finally,we critically evaluate the notion that therapies targeting LRRK2 and GBA might be relevant to a wider segment of PD patients,beyond those that actually carry risk variants of these genes. | Christian U.von Linstow Ziv Gan-Or Patrik Brundin | 2020 | Translational Neurodegeneration2020，9，4： | 1 |
| 16 | Physical training may enhance beta-cell function in type 2 diabetes显示文摘 | Dela F Von Linstow ME Mikines KJ | | 0，，05： | 1 |
| 17 | Human metapneumovirus and respiratory syncytial virus in hospitalized danish children with acute espiratory ract infection显示文摘 | Henrik Larsen H Eugen-Olsen J | 2004 | Scand J Infect Dis2004，36，8： | 1 |
| 18 | An 8-year follow-up study of pulmonary function in patients with rheumatoid arthritis显示文摘 | Linstow M Ulrik CS Kriegbaum NJ | | 0，，： | 1 |
| 19 | Risk factors for onset of asthma : a12-year prospective follow-up study 显示文摘 | Porsbjerg C yon Linstow ML Ulrik CS | 2006 | Chest2006，129，2： | 1 |
| 20 | Risk factors for onset of asthma: a 12-year prospective follow-up study显示文摘 | Porsbjerg C yon Linstow ML Ulrik CS | 2006 | Chest2006，129，2： | 1 |
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