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您的检索式：作者名="Linlan Song"
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| 1 | Research on Link Quality Estimation Mechanism for Wireless Sensor Networks Based on Support Vector Machine显示文摘In the application of Wireless sensor networks(WSNs),effective estimation for link quality is a basic issue in guarantying reliable data transmission and upper network protocol performance.A link quality estimation mechanism is proposed,which is based on Support vector machine(SVM) with multi-class classification.Under the analysis of the wireless link characteristics,two physical parameters of communication,Receive signal strength indicator(RSSI) and Link quality indicator(LQI),are chosen as estimation parameters.The link quality is divided into five levels according to Packet reception rate(PRR).A link quality estimation model based on SVM with decision tree is established.The model is built on kernel functions of radial basis and polynomial respectively,in which RSSI,LQI are the input parameters.The experimental results show that the model is reasonable.Compared with the recent published link quality estimation models,our model can estimate the current link quality accurately with a relative small number of probe packets,so that it costs less energy consumption than the one caused by sending a large number of probe packets.So this model which is high efficiency and energy saving can prolong the network life. | SHU Jian LIU Song LIU Linlan ZHAN Liqin HU Gang | 2017 | Chinese Journal of Electronics2017，26，2： | 12 |
| 2 | Whole-exome mutational landscape of metastasis in patient-derived hepatocellular carcinoma cells显示文摘In order to explore the genomic basis for liver cancer metastasis,whole-exome sequencing(WES)was performed on patient-derived hepatocellular carcinoma(HCC)cell lines with differential metastatic potentials and analyzed their clonal evolution relationships.An evolutionary tree based on genomic single nucleotide polymorphism(SNP)was constructed in MegaX software.The WES data showed that the average percentage of heterogeneous mutations in each HCC cell lines was 16.55%(range,15.38%e18.17%).C:G>T:A and T:A>C:G somatic transitions were the two most frequent substitutions.In these metastatic HCC cell lines,non-silent gene mutations were found in 21.88%of known driver genes and 10 classical signaling pathways.The protein interaction network was constructed by STRING,and hub genes were found in the shared trunk mutation genes and the heterogeneous branch mutations respectively.In cBioPortal database,some of the selected hub genes were found to be associated with poor overall survival(OS)of HCC patients.Among the mutated HCC driver genes,a novel KEAP1 mutation with a homozygous frameshift truncation at the c-terminal Nrf2 binding region was detected and verified in MHCC97-H and HCC97LM3 cells.In conclusion,WES data demonstrate that HCC cell lines from tumor biopsy specimens of the same patient have obtained different metastatic potentials through repeated selection in rodents in vivo,and they do indeed have a genetic relationship at the genomic level. | Qian Zhou Zuli Li Linlan Song Di Mu Jin Wang Li Tian Yong Liao | 2020 | Genes & Diseases2020，7，3： | 1 |
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