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| 1 | Intake of Volatile N-nitrosamines and Their Ability to Exogenously Synthesize in the Diet of Inhabitants from High-risk Area of Esophageal Cancer in Southern China显示文摘Objective Nan'so County in Guandong Province is a high-risk area of esophageal cancer in Southern China .Of the suspected etiological factors in the environment ,N-nitrosamines and their precursors have received the greatest attention.Methods Sixty samples of the diet ingested by the inhabitants were collected and detected for volatile N-nitrosamines and their precursors.Five N-nitrosamines detected by Gas Chromatography-Thermal Energy Analyzer were N-nitrosodimethylamine,N-nitrosodiethylamine,N-nitrosopyrrolidine,N-nitrosopiperidine and N-nitrosomethyl-benzylamine.Results The average content of 5 volatile N-nitrosamines in the diet was 312.0μg/kg(meian).The daily intake of the nitrosamines was 286.5μg/head/day.Only the ability to exogenously synthesize N-nitrosopiperidine was powerful among 5 volatile N-nitrosamines.By a computerized stepwise regression analysis and curve fitting,we studied the correlation among the nitrosamines,the precursors and the major food items in the samples.Conclusion It demonstrated that a relatively high content of volatile N-nitrosamines was present in the diet collected in the area. | LINKUN SHENZHONG-YING 等 | 2002 | Biomedical and Environmental Sciences2002，15，4： | 6 |
| 2 | The molecular dynamics of neural metabolism during the action potential显示文摘Neural information processing is tightly coupled to both energy consumption and derivation from substrates.In this study,the energy function of the neuron during the action potential(AP)is described and analyzed.It has been observed that energy consumption during the AP does not match predictions of the conventional theory of neural energy dynamics.On short time scales,neural energy expenditure shifts between positive and negative phases.During the AP,the energy source switches from neuronal stores(positive expenditure or net consumption)to exploitation of external substrates,specifically the glucose and oxygen carried in cerebral blood(the negative consumption phase).Based on the idea of reductionism,this paper demonstrates how ion channels,membrane pumps and transporters,ionotropic and metabotropic receptor signaling pathways,astrocyte glycolysis and the production lactate,and the glutamate-glutamine cycle all serve to relate cerebral blood flow and neuronal metabolism to neuronal activity and so maintain neuronal energy charge during the AP. | ZHENG HongWen WANG RuBin QIAO LinKun DU Ying | 2014 | Science China(Technological Sciences)2014，57，5： | 5 |
| 3 | 干旱胁迫的水稻根高效酵母双杂交体系建立显示文摘采用SMART技术在酵母菌株AH109中构建了干旱胁迫下水稻根部全长cDNA文库,采用改进的滤膜杂交方法建立了高效酵母杂交体系,以抗旱相关水稻转录调控因子OsWRKY71基因作为诱饵对该方法进行检验。实验获得的酵母杂交文库容量为4.9×106,平均插入片段为800bp,达到了基因分离和克隆等后续研究的标准。同时采用滤膜杂交法将文库的杂交效率提高到了6.9%,是液体杂交法的6倍以上。该方法不需要特殊的设备,且具有低消耗和高效率的特点,可用于高通量酵母双杂交分析。 | 付坚 Linkun GU 郭怡卿 Liyuan ZHANG 王玲仙 李定琴 王波 Jeff Qingxi SHEN 程在全 | 2013 | 中国水稻科学2013，27，2： | 2 |
| 4 | Osseointegration of orthodontic micro-screws after immediate and early loading 显示文摘 | Linkun Zhang Zhihe Zhao Yu Li | 2010 | Angle Orthod2010，80，： | 1 |
| 5 | Collaborative Offloading Method for Digital Twin Empowered Cloud Edge Computing on Internet of Vehicles显示文摘Digital twinning and edge computing are attractive solutions to support computing-intensive and servicesensitive Internet of Vehicles applications.Most of the existing Internet of Vehicles service offloading solutions only consider edge–cloud collaboration,but the collaboration between small cell eNodeB(SCeNB)should not be ignored.Service delays far lower than offloading tasks to the cloud can be obtained through reasonable collaborative computing between nodes.The proposed framework realizes and maintains the simulation of collaboration between SCeNB nodes by constructing a digital twin that maintains SCeNB nodes in the central controller,thereby realizing user task offloading positions,sub-channel allocation,and computing resource allocation.Then an algorithm named AUC-AC is proposed,based on the dominant actor–critic network and the auction mechanism.In order to obtain a better command of global information,the convolutional block attention mechanism(CBAM)is used in the digital twin of each SCeNB node to observe its environment and learn strategies.Numerical results show that our experimental scheme is better than several baseline algorithms in terms of service delay. | Linjie Gu Mengmeng Cui Linkun Xu Xiaolong Xu | 2023 | Tsinghua Science and Technology2023，28，3： | 1 |
| 6 | Erythropoietin Ameliorates Renal Ischemia and Reperfusion Injury via Inhibiting Tubulointerstitial Inflammation显示文摘 | Linkun Hu Cheng Yang Tian Zhao Ming Xu Qunye Tang Bin Yang Ruiming Rong Tongyu Zhu | 2012 | Journal of Surgical Research2012，，1： | 1 |
| 7 | Enhanced resistance to coxsackievirus B3-induced myocarditis by intransal co-immunization of lymphotactin gene encapsulated in chitosan partical显示文摘 | YAN Y WEI X LINKUN HU | 2009 | Virology2009，386，2： | 1 |
| 8 | Osseointegration of orthodontic micro-screws 'after immediate and early loading 显示文摘 | Linkun Zhang Zhihe Zhao Yu Li | 2010 | Angle Orthod2010，80，： | 1 |
| 9 | The Study on Bamboo Microfibers Isolated by Steam Explosion and Their Comprehensive Properties显示文摘To overcome the shortage of wood resources as well as to develop novel natural fibers materials,the Chimonobambusa quadrangularis(CQ)and Qiongzhuea tumidinoda(QT)planted in Southwest China were effectively isolated by the steam explosion(SE).The fine and uniform bamboo microfibers derived from CQ and QT were obtained,and their smallest average widths were 12.62μm and 16.05μm,respectively.The effects of steam explosion on the micro-morphology,chemical composition,thermal stability,crystallinity,surface wettability,and mechanical properties of bamboo microfibers were comprehensively investigated.The results showed that the relative content of cellulose in bamboo microfibers increased but the hemicellulose and lignin contents decreased after SE.The degrees of crystallinity for CQ and QT increased from 40.49%and 39.46%to 68.90%and 55.78%,respectively.The thermal stability and surface hydrophilicity were also improved.The CQ microfibers had a maximum decomposition temperature of 2.79°C,a tensile strength of 58.54 MPa,an elongation at break of 0.6%,and a water contact angle of 2.7°higher than those of the QT microfibers. | Qiushi Li Ronggang Luo Yu Chen Jinhui Xiong Bei Qiao Xijuan Chai Linkun Xie Juan Wang Lianpeng Zhang Siqun Wang Guanben Du Kaimeng Xu | 2023 | Journal of Renewable Materials2023，11，6： | 0 |
| 10 | Expression and Response Analysis of NCED Gene of Zoysia japonica in Initial Infection Stage of Rhizoctonia solani显示文摘[Objective] The paper was to analyze the expression and response mechanism of NCED gene of Zoysia japonica in initial infection stage of Rhizoctonia solani. [Method] The NCED gene fragments of Z. japonica‘Zenith'were screened and cloned on the basis of transcriptome data. The expression patterns of NCED gene in initial infection stage of R. solani( 0-48 h) were obtained via real-time quantitative PCR. [Result] The expression level of NCED gene in stress treatment was higher than that without infection,which first increased then decreased with the extension of time,and reached the maximum at 36 h. Further detection of ABA level in‘Zenith'roots showed that the change trend of ABA level within 0-48 h was consistent with the expression pattern of NCED gene,and flattened out after 48 h. [Conclusion] NCED gene regulates the synthesis of phytohormone ABA and probably further involves in plant disease resistance. | Li Linkun He Xusheng Zeng Huiming | 2017 | Plant Diseases and Pests2017，8，5： | 0 |
| 11 | The Rb-Sr age and geological implication of alkaline syenitic complex from Liangtun-Kuangdonggou at Gaixian,eastern Liaoning Province显示文摘Liangtun-Kuangdonggou complex, 30 km southeast of Gaixian Town, Liaoning Province, is composed of aegirine-augite hornblende syenite, aegirine-augite syenite, hornblende syenite, pyroxene syenite and syeno-aegirinolite. Rb-Sr isotopic data to the complex are reported and used for discussion of chronology and geological implication. They show that the complex occurred in early Proterozoic and is a tectonic sign of extension setting. Moreover, the date indicates that the Liaohe Group, which is metamorphic wall rock of the complex, formed over 1 900 Ma ago. | Baoliang Xu Guohan Yan Baolei Mu Linkun Tan Zhongfu He Guangsheng Qiao Renhu Zhang | 1999 | Chinese Science Bulletin1999，44，8： | 0 |
| 12 | Two new species of hydromedusa(Cnidaria)from the Leizhou Bay,the northern South China Sea显示文摘Two previously unknown species of hydromedusae,i.e.Bougainvillia leizhouensis Xu,Guo&Wang,sp.nov.and Octocannoides tetranema Xu,Guo&Wang,sp.nov.were found in plankton samples collected during oceanographic cruises along the Leizhou Bay of the northern South China Sea.All new species are described and illustrated here.Identification keys to the known species of genera Bougainvillia and Octocannoides,and the genera of family Octocannoididae are provided,respectively.In addition,the genus name Pedunculus Xu,Huang&Guo,2019 is preoccupied,and Stylogastria Xu,Huang&Guo,nom.nov.is proposed to replace it.All type specimens are deposited in the College of Ocean and Earth Sciences,Xiamen University. | Xuefeng Wang Liyi Lu Shenzeng Zhang Linkun Lin Zhenzu Xu Donghui Guo Jiaqi Huang | 2021 | Zoological Systematics2021，46，3： | 0 |
| 13 | Unique Ligand Exchange Dynamics of Metal-Organic Polyhedra for Vitrimer-like Gas Separation Membranes显示文摘Metal-organic polyhedra(MOPs)possess a microporous framework and impose hierarchical constraints on their surface ligands,leading to the long-ignored,logarithmic ligand exchange dynamics.Herein,polymer networks with MOP as nanoscale cross-linkers(MOP-CNs)can integrate unique ligand exchange dynamics and microporosity,affording vitrimer-like gas separation membranes with promising mechanical performance and(re)processability.All the ligands on the MOP surfaces are confined and correlated via a 3D coordination framework and their neighboring spaces,giving rise to a high energy barrier for ligand exchange.Therefore,MOP-CNs demonstrate high mechanical strengths at room temperature due to their negligible ligand dynamics.The thermo-activated ligand exchange process with integrated network topology enables facile(re)processing and high solvo-resistance at high temperatures.This facilitates Arrhenius type temperature dependence of flowability and stress relaxation,giving rise to the simultaneous achievement of promising mechanical strengths and(re)processability.Finally,the cage topologies of MOPs endow the materials with a bonus microporous feature and spur their applications as gas separation membranes. | Mingxin Zhang Haitao Yu Qin Zou Zi-Ang Li Yuyan Lai Linkun Cai Panchao Yin | 2022 | CCS Chemistry2022，4，11： | 0 |
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