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| 1 | Subcycle control of terahertz waveform polarization using all-optically induced transient metamaterials显示文摘Coherent radiation with frequencies ranging from 0.3 to 30 THz has recently become accessible using femtosecond laser technology.These terahertz(THz)waves have already been applied in spectroscopy and imaging and can be manipulated using static optical elements such as lenses,polarizers and filters.However,ultrafast modulation of THz radiation is required as well,for instance,in short-range wireless communication or for preparing shaped THz transients for the coherent control of numerous material excitations.Here,we demonstrate an all-optically created transient metamaterial that allows us to manipulate the polarization of THz waveforms with subcycle switch-on times.The polarization-modulated pulses are potentially interesting for controlling elementary motions such as the vibration of crystal lattices,the rotation of molecules and the precession of spins. | N Kamaraju Andrea Rubano Linke Jian Surajit Saha T Venkatesan Jan Notzold R Kramer Campen Martin Wolf Tobias Kampfrath | 2014 | Light(Science & Applications)2014，3，1： | 5 |
| 2 | Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy显示文摘AIM: To study the prognostic value of adjuvant chemo-therapy in patients with pancreatic, ductal adenocar-cinoma.METHODS: Lymph nodes from 106 patients with resectable pancreatic ductal adenocarcinoma were systematically sampled. A total of 318 lymph nodes classified histopathologically as tumor-free were examined using sensitive immunohistochemical assays. Forty-three (41%) of the 106 patients were staged as pT1/2, 63 (59%) as pT3/4, 51 (48%) as pN0, and 55 (52%) as pN1. The study population included 59 (56%) patients exhibiting G1/2, and 47 (44%) patients with G3 tumors. Patients received no adjuvant chemo- or radiation therapy and were followed up for a median of 12 (range: 3.5 to 139) mo.RESULTS: Immunostaining with Ber-EP4 revealed nodal microinvolvement in lymph nodes classified as “tumor free” by conventional histopathology in 73 (69%) out of the 106 patients. Twenty-nine (57%)of 51 patients staged histopathologically as pN0 had nodal microinvolvement. The five-year survival probability for pN0-patients was 54% for those without nodal microinvolvement and 0% for those with nodal microinvolvement. Cox-regression modeling revealed the independent prognostic effect of nodal microinvolvement on recurrence-free (relative risk 2.92, P = 0.005) and overall (relative risk 2.49, P = 0.009) survival.CONCLUSION: The study reveals strong and independent prognostic significance of nodal microinvolvement in patients with pancreatic ductal adenocarcinoma who have received no adjuvant therapy. The addition of immunohistochemical findings to histopathology reports may help to improve risk stratification of patients with pancreatic cancer. | Emre F Yekebas Dean Bogoevski Michael Bubenheim Bjrn-Christian Link Jussuf T Kaifi Robin Wachowiak Oliver Mann Asad Kutup Guellue Cataldegirmen Lars Wolfram Andreas Erbersdobler Christoph Klein Klaus Pantel Jakob R Izbicki | 2006 | World Journal of Gastroenterology2006，12，40： | 3 |
| 3 | Quality criteria for treatment of colorectal cancer:From a surgeon's viewpoint显示文摘 | Link KH Kommann M Bittner R | 2010 | Chirurg2010，81，3： | 1 |
| 4 | Expression and function of serum amyloid A,a majoracute phase protein,in normal and disease states 显示文摘 | URIELI-SHOVAL S LINKE R P MATZNER Y | 2000 | Curr Opin Hematol2000，7，1： | 1 |
| 5 | Detection of 140 clinically relevant antibiotic-resistance genes in the plasmid metagenome of wastewater treatment plant bacte- ria showing reduced susceptibility to selected antibiotics 显示文摘 | Szczepanowski R Linke B Krahn I | 2009 | Microbiology- SGM2009，155，： | 1 |
| 6 | Long-term follow up of factual knowledge after a single,randomised problem-based learning course显示文摘 | HERZIG S LINKE R M MARXEN B | 2003 | BMC Medical Education2003，，3： | 1 |
| 7 | Monodisperse Double Emulsions Generated from a Microcapillary Device 显示文摘 | Utada A S Lorenceau E Link D R | 2005 | Science2005，308，5721： | 1 |
| 8 | Geometrically mediated breakup of drops in microfuidic devices显示文摘 | LINK D R ANNA S L WEITZ D A | 2004 | Physical Review Letters2004，92，05： | 1 |
| 9 | Influence of eranio- plasty on postural blood flow regulation, cerebrovascular reserve capacity, and cerebral glucose metabolism 显示文摘 | Winkler P A Stummer W Linke R | 2000 | J Neurosurg2000，93，1： | 1 |
| 10 | Antibody-positive paraneoplastic neurologic syndromes: value of CT and PET for tu- mor diagnosis显示文摘 | Linke R Schroeder M Helmberger T | 2004 | Neurology2004，63，2： | 1 |
| 11 | Optical properties and chemistry of graptolite periderm following labo- ratory simulated maturatin 显示文摘 | Bustin R M Link C Goodarzi F | 1989 | Org Geochem1989，14，： | 1 |
| 12 | Monodisperse double emulsions generated from a microeapillary device 显示文摘 | Utada A S Lorenceau E Link D R | 2005 | Science2005，308，5721： | 1 |
| 13 | Influence of cranioplasty on postural blood flow regulation,cerebrovascular reserve capaci-ty,and cerebral glucose metabolism显示文摘 | Winkler PA Stummer W Linke R | 2000 | J Neurosurg2000，93，1： | 1 |
| 14 | Impact of ^131 I SPECT/ spiral CT on nodal staging of differentiated thyroid carcinoma at the first radioablation显示文摘 | Schmidt D Szikszai A Linke R | 2009 | J Nucl Med2009，50，1： | 1 |
| 15 | Machining hard materials with geometrically defined cutting edges-field of applications and limitations显示文摘 | Konig W Klinger M Link R | 1990 | Annals of the CIRP1990，39，1： | 1 |
| 16 | Composite concrete-steel plate walls : analysis and behavior 显示文摘 | Link R A Elwi A E | 1995 | Journal of Structural Engineering ASCE1995，121，2： | 1 |
| 17 | Impact of 1311 SPECT/spiral CT on nodal staging of differen- tiated thyroid carcinoma at the first radioablation 显示文摘 | Schmidt D Szikszai A Linke R | 2009 | J Nucl Med2009，50，1： | 1 |
| 18 | Circulating angiopoietins and cardiovascular mortality in cardiogenic shock显示文摘 | Link A Pss J Rbah R | 2013 | Eur Heart J2013，34，22： | 1 |
| 19 | Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure:a randomized trial显示文摘 | Hambrecht R Gielen S Linke A | 2000 | JAMA2000，283，23： | 1 |
| 20 | Increased accumulation of skin advanced glycation end-products precedes and correlates with clinical manifestation of diabetic neuropathy 显示文摘 | Meerwaldt R Links TP Graaff R | 2005 | Diabetologia2005，48，： | 1 |
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